Abstract:
:Cardiovascular function during sleep was studied in 14 (6 males, 8 females) healthy, active, older adults (57-70) years). Noninvasive measures of stroke volume (SV), heart rate (HR), cardiac output (CO), pre-ejection period (PEP), and left ventricular ejection time (LVET) were taken using impedance cardiography and computer-based "ensemble" averaging. Data were obtained from the last of three nights of normal sleep and on a night following an hour walk on a treadmill at 60% VO2 max. Cardiovascular measures revealed patterns during sleep which parallel those seen in younger subjects, i.e. a progressive decline in SV and CO, unaffected by EEG sleep stage. The trend was different for heart rate, which showed only an initial decline at sleep onset. No consistent trends were seen for LVET, whereas PEP declined to a low point 1.5 h after sleep onset. Following exercise, HR was slightly elevated during the first 3 h of sleep. In contrast, SV and CO were reduced during the period of sleep between 1 and 4 h after sleep onset; this difference was observed primarily in the women (N = 8). The results suggest that an acute increase in daily activity of older adults induces only minor changes in nocturnal cardiac function.
journal_name
Exp Gerontoljournal_title
Experimental gerontologyauthors
Bevier WC,Bunnell DE,Horvath SMdoi
10.1016/0531-5565(87)90031-3subject
Has Abstractpub_date
1987-01-01 00:00:00pages
329-37issue
5eissn
0531-5565issn
1873-6815journal_volume
22pub_type
杂志文章abstract::Rodent animal models take at least 18months to develop aging phenotypes for researchers to investigate the mechanism of age-related metabolic complications. Senescence-accelerated mouse prone 8 (SAMP8) shortens the process of aging and may facilitate an alternative model for studying age-related insulin resistance. Th...
journal_title:Experimental gerontology
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journal_title:Experimental gerontology
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2004.05.005
更新日期:2004-09-01 00:00:00
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journal_title:Experimental gerontology
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journal_title:Experimental gerontology
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journal_title:Experimental gerontology
pub_type: 历史文章,杂志文章
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(01)00133-4
更新日期:2001-09-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.12.010
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2012.02.003
更新日期:2013-01-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(89)90030-2
更新日期:1989-01-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/s0531-5565(99)00087-x
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2006.09.003
更新日期:2007-03-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.05.020
更新日期:2017-10-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2005.10.006
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2014.10.005
更新日期:2014-12-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(96)00172-6
更新日期:1997-07-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2011.06.001
更新日期:2011-10-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/0531-5565(92)90012-o
更新日期:1992-09-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2009.05.004
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pub_type: 杂志文章,评审
doi:10.1016/j.exger.2020.111220
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2018.01.020
更新日期:2018-04-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2015.11.001
更新日期:2015-12-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2008.05.015
更新日期:2008-08-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2020.111098
更新日期:2020-11-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/s0531-5565(97)00059-4
更新日期:1998-01-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2020.110871
更新日期:2020-02-06 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.09.019
更新日期:2018-07-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(94)90061-2
更新日期:1994-01-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2017.12.002
更新日期:2018-02-01 00:00:00