Abstract:
:The neurotensin-cell is identified immunohistochemically and ultrastructurally by differential counting of endocrine cells in the gut of a primate (Tupaia belangeri). Utilizing light microscopy, the EC-cells are identified by the Masson-Fontana silver stain; with the same method the neurotensin cells are not stained. The other endocrine cells have been quantified in the small intestine using the peroxidase-antiperoxidase stain with antisera against glucagon, somatostatin, cholecystokinin, gastrin, secretin, pancreatic polypeptide, gastric inhibitory peptide and neurotensin. In the ileal mucosa of Tupaia, the most frequent endocrine cell is the EC-cell followed by the glucagonoid cell, (L-cell). The immunoreactive neurotensin cell represents the third most frequent endocrine cell in this region. On the ultrastructural level, this third most frequent endocrine cell is a heretofore undescribed cell, the N-cell, containing electron dense secretory granules measuring 335 +/- 87 nm in diameter.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Helmstaedter V,Feurle GE,Forssmann WGdoi
10.1007/BF00220968subject
Has Abstractpub_date
1977-11-23 00:00:00pages
445-52issue
4eissn
0302-766Xissn
1432-0878journal_volume
184pub_type
杂志文章abstract::A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar ce...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00235169
更新日期:1979-01-01 00:00:00
abstract::In the intestine of the filtering zooids of B. schlosseri three segments can be distinguished. In the intermediate segment the epithelium, which is encrusted by the ampullae of the pyloric gland, shows marked aspects of alteration. In the proximal and distal segments, ciliated mucous, vacuolated and endocrine-like cel...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219771
更新日期:1977-08-26 00:00:00
abstract::Human gingival fibroblasts were cultured with collagen fibrils. The precise process of collagen phagocytosis and the relationship between acid phosphatase activity and intracellular degradation of collagen were investigated by cytochemical methods at the ultrastructural level. The collagen fibrils were first engulfed ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213929
更新日期:1986-01-01 00:00:00
abstract::The amniotic epithelium constitutes a diffusion barrier controlling the passage of solutes and water between the amniotic cavity and maternal circulation. With the present immunocytochemical approach, we have shown that several major components of the cyto-skeleton, i.e., actin, alpha-actinin, spectrin and ezrin, are ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318194
更新日期:1991-11-01 00:00:00
abstract::The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051142
更新日期:1998-09-01 00:00:00
abstract::The intestine, which is exposed to nutrition and to food-derived antigens and microbes including viruses and bacteria, might be an important site for the immune response. Crucial structural and functional differences exist between the small and large intestine, regional differences even having been demonstrated within...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0706-4
更新日期:2003-07-01 00:00:00
abstract::Electron-cytochemical localization of alkaline phosphatase activity was performed on G cells of Necturus maculosus antral mucosa. Alkaline phosphatase activity was localized to the nuclear membrane, the Golgi/endoplasmic reticulum, and the limiting membranes of G cell peptide-secretion vesicles. There was no specific ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218867
更新日期:1989-12-01 00:00:00
abstract::The fine structure of synapses, their distribution and arrangement in the ventral nerve cord of Peripatoides leuckarti (phylum Onychophora) is described. The asymmetric synaptic junctions show a well developed synaptic cleft (300 A) and pre- and subsynaptic electron dense apposition. They frequently show an array of p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224940
更新日期:1978-01-31 00:00:00
abstract::To identify structures involved in the translocation of the synaptic vesicles towards the presynaptic membrane, an ultrastructural study has been undertaken by means of (1) the E-PTA stain and (2) the HMM-labeling procedure. Using serial sections of E-PTA stained nervous tissue, especially those made in transversal an...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219841
更新日期:1975-06-27 00:00:00
abstract::The development of the heterophil granulocytes in the bone marrow of the guinea pig is described. During the maturation of these cells, three types of granule are formed, not only the azurophil and specific granules already described in other mammals but also a third type of granule referred to here as the nucleated g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220388
更新日期:1978-11-20 00:00:00
abstract::In recent years, data have accumulated suggesting that the role of neurotrophins and Trk receptors may not be limited to the nervous system, and the presence of these substances has been detected in a variety of vertebrate and invertebrate non-nervous tissues. This study was designed to map the expression of immunorea...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000181
更新日期:2000-04-01 00:00:00
abstract::Cestodes (tapeworms) are a derived, parasitic clade of the phylum Platyhelminthes (flatworms). The cestode body wall represents an adaptation to its endoparasitic lifestyle. The epidermis forms a non-ciliated syncytium, and both muscular and nervous system are reduced. Morphological differences between cestodes and fr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0687-8
更新日期:2003-03-01 00:00:00
abstract::Ex-fissiparous planarians produce infertile cocoons or, in very rare cases, cocoons with very low fertility. Here, we describe the features of programmed cell death (PCD) occurring in the hyperplasic ovary of the ex-fissiparous freshwater planarian Dugesia arabica that may explain this infertility. Based on TEM result...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1971-0
更新日期:2014-11-01 00:00:00
abstract::Stereological studies showed that treatment of normal adult human adrenocortical cells in primary culture with ACTH or cyclic-AMP for 2 days results in similar increases in the volume of cells, of the mitochondrial and "membrane space" compartments and of the surface area of the smooth endoplasmic reticulum and mitoch...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218169
更新日期:1978-07-05 00:00:00
abstract::The formaldehyde-induced fluorescence technique had shown 5-hydroxytryptamine-containing enteric neurons in the intestine of the teleost Platycephalus bassensis, but did not reveal such neurons in the intestine of Tetractenos glaber or Anguilla australis. Re-examination of these animals with 5-hydroxytryptamine immuno...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226505
更新日期:1988-01-01 00:00:00
abstract::Complex carbohydrates in secretory granules and at the apical cell surface of mouse gastric mucoid cells were studied during embryogenesis and in the early postnatal period by various cytochemical methods; the periodic acid-thiocarbohydrazide-silver proteinate (PA-TCH-SP) and tannic acid-uranyl acetate (TA-UA) procedu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214559
更新日期:1985-01-01 00:00:00
abstract::The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216767
更新日期:1981-01-01 00:00:00
abstract::The prothoracicotropic hormone (PTTH), which stimulates ecdysteroid synthesis in the prothoracic glands, is produced, in the dorso-lateral protocerebrum of Manduca sexta, by paired peptidergic neurons, the lateral neurosecretory cell group III (L-NSC III). Our study revealed ultrastructural features of L-NSC III, iden...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00303082
更新日期:1994-07-01 00:00:00
abstract::Ontogenetic development of GRF-containing neurons in the rat hypothalamus was studied employing antisera which were generated against hpGRF (1-44)NH2 and rhGRF(1-43)OH: anti-hpGRF-C and -rhGRF sera recognize the species-specific C-terminal portions of the peptides, and anti-hpGRF-MC and -N sera recognize hpGRF(27-44)N...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225416
更新日期:1985-01-01 00:00:00
abstract::In an ultrastructural study on the spermiogenesis of the rainbow trout (Salmo gairdneri R.) four spermatogenetic stages were identified. In young round spermatids, the nuclear chromatin was first heterogeneous (euchromatin and heterochromatin). Subsequently, it became more homogeneous and started to condense in the fo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238295
更新日期:1983-01-01 00:00:00
abstract::Recent evidence indicates that many molecules involved in generating and patterning the limbs also play a role during craniofacial morphogenesis. On the surface, this is an unexpected finding given that these regions of the body have separate evolutionary origins, are composed of different embryonic tissues, and are q...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s004410051271
更新日期:1999-04-01 00:00:00
abstract::Taste buds and the peripheral nerves innervating them are two important components of the peripheral gustatory system. They require appropriate connections for the taste system to function. Neurotrophic factors play crucial roles in the innervation of peripheral sensory organs and tissues. Both brain-derived neurotrop...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0833-7
更新日期:2009-09-01 00:00:00
abstract::Electron-microscopic evidence indicates that during conditions of high hormone demand such as lactation there is a dramatic reduction in the number of fine glial processes which are normally interposed between magnocellular neuroendocrine cell somata in the supraoptic nucleus (SON). The purpose of this study was to co...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225557
更新日期:1985-01-01 00:00:00
abstract::Although Hertwig's epithelial root sheath (HERS) performs an important function in the formation of the tooth root, the developmental mechanisms that control HERS growth and differentiation remain to be thoroughly elucidated. Bone morphogenetic protein 4 (BMP4), which is secreted by mesenchymal cells, acts on the dent...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0655-z
更新日期:2008-09-01 00:00:00
abstract::Back-labeling of regenerated electromotor neurons in the teleost Sternarchus albifrons was performed to test the hypothesis that, in regenerated spinal cord, incorrectly located electromotor neurons are eliminated because their axons do not reach the correct target area (electric organ). In each cross section examined...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217166
更新日期:1985-01-01 00:00:00
abstract::Seasonal changes have been detected in the ultrastructure of brown adipose tissue (BAT) of the common shrew, Sorex araneus (a true nonhibernator) living under natural conditions and collected at the time when the most representative growth phase of the animal for the given season could be expected. In summer and autum...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233501
更新日期:1981-01-01 00:00:00
abstract::Over the past decade, adult stem cells have attracted great attention because of their ability to potentially regenerate desired tissues or entire organs. With the emergence of nanomaterial-based gene therapy, adult stem cells have been considered as a proper tool for the biomedical field. In this study, we utilized o...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2235-3
更新日期:2015-12-01 00:00:00
abstract::Immunohistochemical localization of luteinizing hormone-releasing hormone (LH-RH), during different phases of the estrus cycle, in the preoptic, suprachiasmatic and arcuate nuclei, and in the OVLT of rats, with special emphasis on the ependymal cells, was studied by light, fluorescent and electron microscopy, by using...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221371
更新日期:1976-10-06 00:00:00
abstract::Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction and eventual organ failure. Therefore, the development of effective anti-fibrotic therapies is urgently required. During fibrogenesis, complex interplay occurs between cellular and extracellular matrix components of...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-016-2407-9
更新日期:2016-09-01 00:00:00
abstract::Serotonin immunoreactivity was localized in hearts of the opisthobranch gastropod, Aplysia californica (sea hare) and several species of bivalve mollusks, the heterodonts, Mercenaria mercenaria (quahog or cherry stone clam), Protothaca staminea (little neck clam), and the pteriomorphs, Hinnites multirugosus (rock scal...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00353897
更新日期:1992-09-01 00:00:00