Abstract:
:Single-cell sequencing (SCS) has impacted many areas of cancer research and improved our understanding of intratumor heterogeneity, the tumor microenvironment, metastasis, and therapeutic resistance. The development and refinement of SCS technologies has led to massive reductions in costs, increased cell throughput, and improved reproducibility, paving the way for clinical applications. However, before translational applications can be realized, there are a number of logistical and technical challenges that must be overcome. This review discusses past cancer research studies, emerging technologies, and future clinical applications that are bound to transform cancer medicine.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Lim B,Lin Y,Navin Ndoi
10.1016/j.ccell.2020.03.008subject
Has Abstractpub_date
2020-04-13 00:00:00pages
456-470issue
4eissn
1535-6108issn
1878-3686pii
S1535-6108(20)30148-3journal_volume
37pub_type
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