Abstract:
:Metastasis and therapy resistance are cardinal features of pancreatic ductal adenocarcinoma, a commonly lethal malignancy. In this issue of Cancer Cell, Steele et al. show that CXCR2 expression and neutrophils are required for metastasis. In mice treated with advanced disease, inhibiting both CXCR2 and PD1 cooperatively but not individually prolongs survival.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Stromnes IM,Greenberg PDdoi
10.1016/j.ccell.2016.05.013subject
Has Abstractpub_date
2016-06-13 00:00:00pages
774-776issue
6eissn
1535-6108issn
1878-3686pii
S1535-6108(16)30218-5journal_volume
29pub_type
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