Abstract:
:Gene alterations play a prominent role in driving cancer initiation and progression. However, the genetic events that occur in normal cells prior to tumorigenesis are still unknown. Recent studies have started to map somatic mutations in normal human tissues, and here we discuss their implications for our understanding of tumorigenesis.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Wijewardhane N,Dressler L,Ciccarelli FDdoi
10.1016/j.ccell.2020.11.002subject
Has Abstractpub_date
2020-11-17 00:00:00eissn
1535-6108issn
1878-3686pii
S1535-6108(20)30594-8pub_type
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