A TeNaCious foundation for the metastatic niche.

Abstract:

:In the July issue of Nature Medicine, Massagué and colleagues define a biphasic role for the extracellular matrix protein tenascin C as a metastatic niche component in lung colonization by breast cancer cells. These results provide a rationale for designing therapies targeting metastatic progression by disrupting its very foundations.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Matei I,Ghajar CM,Lyden D

doi

10.1016/j.ccr.2011.08.004

subject

Has Abstract

pub_date

2011-08-16 00:00:00

pages

139-41

issue

2

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(11)00272-8

journal_volume

20

pub_type

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