Abstract：
:Recent genomic analyses of pediatric glioblastoma, a poorly understood tumor with dismal outcome, have identified mutations in histone H3 variants that affect critical amino acids in the tail. The findings extend discoveries of chromatin regulator inactivation and gain-of-function mutations by documenting alteration of a modifiable histone residue in human cancer.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Rheinbay E,Louis DN,Bernstein BE,Suvà MLdoi
10.1016/j.ccr.2012.03.001subject
Has Abstractpub_date
2012-03-20 00:00:00pages
329-31issue
3eissn
1535-6108issn
1878-3686pii
S1535-6108(12)00084-0journal_volume
21pub_type
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