Abstract:
:In this issue of Cancer Cell, Wieland et al. uncover a feedback loop in which tumor cells, by augmenting Notch signaling, provoke a senescent and pro-inflammatory state in endothelial cells, promoting neutrophil infiltration, tumor cell adhesion, and metastasis. Interfering with this Notch-dependent crosstalk may be a therapeutic approach to block metastasis.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Guo P,Rafii Sdoi
10.1016/j.ccell.2017.02.016subject
Has Abstractpub_date
2017-03-13 00:00:00pages
301-303issue
3eissn
1535-6108issn
1878-3686pii
S1535-6108(17)30059-4journal_volume
31pub_type
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