Abstract:
:The PI3K signaling axis is frequently activated in cancer resulting from inactivation of its negative regulator PTEN or activating mutations of the p110alpha catalytic subunit of PI3K. In this issue of Cancer Cell, Jaiswal et al. report that mutations in the p85alpha regulatory subunit of PI3K can also activate this pathway in cancer.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Berenjeno IM,Vanhaesebroeck Bdoi
10.1016/j.ccr.2009.11.017subject
Has Abstractpub_date
2009-12-08 00:00:00pages
449-50issue
6eissn
1535-6108issn
1878-3686pii
S1535-6108(09)00393-6journal_volume
16pub_type
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