Does CSF1R Blockade Turn into Friendly Fire?

Abstract:

:In this issue of Cancer Cell, Kumar et al. describe how CSF1R blockade induces not only an expected deprivation of tumor-associated macrophages, but also an accumulation of tumor-infiltrating polymorphonuclear mononuclear cells caused by Cxcl-1 released from cancer-associated fibroblasts.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Greten TF

doi

10.1016/j.ccell.2017.10.012

subject

Has Abstract

pub_date

2017-11-13 00:00:00

pages

546-547

issue

5

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(17)30465-8

journal_volume

32

pub_type

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