Neuroblastoma Metastases: Leveraging the Avian Neural Crest.

Abstract:

:Neuroblastoma, an embryonal cancer of neural crest origin, shows metastases frequently at diagnosis. In this issue of Cancer Cell, Delloye-Bourgeois and colleagues demonstrate that neuroblastoma cell lines and patient-derived xenografts engraft and adopt a metastatic program in chick embryos. They identify Sema3C as a candidate switch that regulates metastatic spread.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Zheng T,Ménard M,Weiss WA

doi

10.1016/j.ccell.2017.09.012

subject

Has Abstract

pub_date

2017-10-09 00:00:00

pages

395-397

issue

4

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(17)30416-6

journal_volume

32

pub_type

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