Lymphotoxins: new targets for hepatocellular carcinoma.

Abstract:

:In this issue of Cancer Cell, Haybaeck et al. unravel the role of lymphotoxin pathway in the development of hepatocellular carcinoma (HCC). Aberrant activation of this cascade in mice livers recapitulates the stages of fibrosis and inflammation that precedes human liver cancer, providing a novel family of potential therapeutic targets.

journal_name

Cancer Cell

journal_title

Cancer cell

authors

Villanueva A,Savic R,Llovet JM

doi

10.1016/j.ccr.2009.09.012

subject

Has Abstract

pub_date

2009-10-06 00:00:00

pages

272-3

issue

4

eissn

1535-6108

issn

1878-3686

pii

S1535-6108(09)00298-0

journal_volume

16

pub_type

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