Abstract：
:PUMA is a pro-apoptotic Bcl-2 family protein that can act as a tumor suppressor or oncogene in different cancers. In this issue, Kim et al. show that PUMA, independent of its apoptotic function, enforces glycolytic metabolism by inhibiting the transport of pyruvate into the mitochondria, promoting hepatocellular carcinoma.
journal_name
Cancer Celljournal_title
Cancer cellauthors
Green DRdoi
10.1016/j.ccell.2019.01.016subject
Has Abstractpub_date
2019-02-11 00:00:00pages
163-165issue
2eissn
1535-6108issn
1878-3686pii
S1535-6108(19)30050-9journal_volume
35pub_type
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