Abstract:
:Conformational changes in the extradiscal regions of rhodopsin induced by illumination were investigated by modifying the visual pigment by mild treatment with cyanogen bromide prior to and after light exposure. Light induced an increased yield of cleavage of the Met bond 253-254 and a new cleavage at the Met bond 155-156 of the rhodopsin polypeptide chain. These residues, located at the beginnings of the membrane-buried helices 6 and 4, respectively, were concluded to become extradiscally exposed upon illumination.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Pellicone C,Nullans G,Virmaux Ndoi
10.1016/0014-5793(85)81138-8subject
Has Abstractpub_date
1985-02-11 00:00:00pages
179-83issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(85)81138-8journal_volume
181pub_type
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