Abstract：
:Memories of experiences that occur around the same time are linked together by a shared temporal context, represented by shared patterns of neural activity. However, shared temporal context may be problematic for selective retrieval of specific memories. Here, we examine intracranial EEG (iEEG) in the human temporal lobe as participants perform a verbal paired associates memory task that requires the encoding of distinct word pairs in memory. We find that the rate of change in patterns of low frequency (3-12 Hz) power distributed across the temporal lobe is significantly related to memory performance. We also find that exogenous electrical stimulation affects how quickly these neural representations of temporal context change with time, which directly affects the ability to successfully form memories for distinct items. Our results indicate that the ability to retrieve distinct episodic memories is related to how quickly neural representations of temporal context change over time during encoding.
journal_name
Nat Communjournal_title
Nature communicationsauthors
El-Kalliny MM,Wittig JH Jr,Sheehan TC,Sreekumar V,Inati SK,Zaghloul KAdoi
10.1038/s41467-018-08189-4subject
Has Abstractpub_date
2019-01-14 00:00:00pages
203issue
1issn
2041-1723pii
10.1038/s41467-018-08189-4journal_volume
10pub_type
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