Particle-resolved topological defects of smectic colloidal liquid crystals in extreme confinement.

Abstract:

:Confined samples of liquid crystals are characterized by a variety of topological defects and can be exposed to external constraints such as extreme confinements with nontrivial topology. Here we explore the intrinsic structure of smectic colloidal layers dictated by the interplay between entropy and an imposed external topology. Considering an annular confinement as a basic example, a plethora of competing states is found with nontrivial defect structures ranging from laminar states to multiple smectic domains and arrays of edge dislocations, which we refer to as Shubnikov states in formal analogy to the characteristic of type-II superconductors. Our particle-resolved results, gained by a combination of real-space microscopy of thermal colloidal rods and fundamental-measure-based density functional theory of hard anisotropic bodies, agree on a quantitative level.

journal_name

Nat Commun

journal_title

Nature communications

authors

Wittmann R,Cortes LBG,Löwen H,Aarts DGAL

doi

10.1038/s41467-020-20842-5

subject

Has Abstract

pub_date

2021-01-27 00:00:00

pages

623

issue

1

issn

2041-1723

pii

10.1038/s41467-020-20842-5

journal_volume

12

pub_type

杂志文章
  • Disinhibition of olfactory bulb granule cells accelerates odour discrimination in mice.

    abstract::Granule cells are the dominant cell type of the olfactory bulb inhibiting mitral and tufted cells via dendrodendritic synapses; yet the factors regulating the strength of their inhibitory output, and, therefore, their impact on odour discrimination, remain unknown. Here we show that GABAAR β3-subunits are distributed ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms9950

    authors: Nunes D,Kuner T

    更新日期:2015-11-23 00:00:00

  • NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.

    abstract::Chronic lymphocytic leukaemia (CLL) is a clonal disorder of mature B cells. Most patients are characterised by an indolent disease course and an anergic phenotype of their leukaemia cells, which refers to a state of unresponsiveness to B cell receptor stimulation. Up to 10% of CLL patients transform from an indolent s...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-017-00830-y

    authors: Märklin M,Heitmann JS,Fuchs AR,Truckenmüller FM,Gutknecht M,Bugl S,Saur SJ,Lazarus J,Kohlhofer U,Quintanilla-Martinez L,Rammensee HG,Salih HR,Kopp HG,Haap M,Kirschniak A,Kanz L,Rao A,Wirths S,Müller MR

    更新日期:2017-10-02 00:00:00

  • Enzymatic aerobic ring rearrangement of optically active furylcarbinols.

    abstract::Biogenic furans are currently discussed as highly attractive alternative feedstock in a post-fossil society; thus, also the creation of sustainable furan valorization pathways appears of great importance. Here an artificial Achmatowicz monooxygenase activity for the aerobic ring expansion of furans is achieved by the ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms6278

    authors: Thiel D,Doknić D,Deska J

    更新日期:2014-10-22 00:00:00

  • The electrophotonic silicon biosensor.

    abstract::The emergence of personalized and stratified medicine requires label-free, low-cost diagnostic technology capable of monitoring multiple disease biomarkers in parallel. Silicon photonic biosensors combine high-sensitivity analysis with scalable, low-cost manufacturing, but they tend to measure only a single biomarker ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms12769

    authors: Juan-Colás J,Parkin A,Dunn KE,Scullion MG,Krauss TF,Johnson SD

    更新日期:2016-09-14 00:00:00

  • Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation.

    abstract::Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelerated protein catabolism. The factors that induce these changes remain unknown. Conversely, functional recovery following...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-14063-8

    authors: Cisterna BA,Vargas AA,Puebla C,Fernández P,Escamilla R,Lagos CF,Matus MF,Vilos C,Cea LA,Barnafi E,Gaete H,Escobar DF,Cardozo CP,Sáez JC

    更新日期:2020-02-26 00:00:00

  • Ultrafast photoinduced band splitting and carrier dynamics in chiral tellurium nanosheets.

    abstract::Trigonal tellurium (Te) is a chiral semiconductor that lacks both mirror and inversion symmetries, resulting in complex band structures with Weyl crossings and unique spin textures. Detailed time-resolved polarized reflectance spectroscopy is used to investigate its band structure and carrier dynamics. The polarized t...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-17766-5

    authors: Jnawali G,Xiang Y,Linser SM,Shojaei IA,Wang R,Qiu G,Lian C,Wong BM,Wu W,Ye PD,Leng Y,Jackson HE,Smith LM

    更新日期:2020-08-10 00:00:00

  • Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.

    abstract::SIRT1, the founding member of the mammalian family of seven NAD(+)-dependent sirtuins, is composed of 747 amino acids forming a catalytic domain and extended N- and C-terminal regions. We report the design and characterization of an engineered human SIRT1 construct (mini-hSIRT1) containing the minimal structural eleme...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms8645

    authors: Dai H,Case AW,Riera TV,Considine T,Lee JE,Hamuro Y,Zhao H,Jiang Y,Sweitzer SM,Pietrak B,Schwartz B,Blum CA,Disch JS,Caldwell R,Szczepankiewicz B,Oalmann C,Yee Ng P,White BH,Casaubon R,Narayan R,Koppetsch K,Bourb

    更新日期:2015-07-02 00:00:00

  • Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly.

    abstract::The maturation of HIV-1 viral particles is essential for viral infectivity. During maturation, many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral RNA. The mechanistic details of the initiation and early stages of capsid assembly remain to be delineated. We present coarse-grai...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms11568

    authors: Grime JMA,Dama JF,Ganser-Pornillos BK,Woodward CL,Jensen GJ,Yeager M,Voth GA

    更新日期:2016-05-13 00:00:00

  • Site-selective photoemission from delocalized valence shells induced by molecular rotation.

    abstract::Due to the generally delocalized nature of molecular valence orbitals, valence-shell spectroscopies do not usually allow to specifically target a selected atom in a molecule. However, in X-ray electron spectroscopy, the photoelectron momentum is large and the recoil angular momentum transferred to the molecule is larg...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4816

    authors: Miron C,Miao Q,Nicolas C,Bozek JD,Andrałojć W,Patanen M,Simões G,Travnikova O,Ågren H,Gel'mukhanov F

    更新日期:2014-05-09 00:00:00

  • Evolutionary and functional impact of common polymorphic inversions in the human genome.

    abstract::Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. Here, we develop a new high-throughput genotyping method based...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12173-x

    authors: Giner-Delgado C,Villatoro S,Lerga-Jaso J,Gayà-Vidal M,Oliva M,Castellano D,Pantano L,Bitarello BD,Izquierdo D,Noguera I,Olalde I,Delprat A,Blancher A,Lalueza-Fox C,Esko T,O'Reilly PF,Andrés AM,Ferretti L,Puig M,Cáce

    更新日期:2019-09-17 00:00:00

  • Transformation of amorphous calcium phosphate to bone-like apatite.

    abstract::Mineralisation of calcium phosphates in bone has been proposed to proceed via an initial amorphous precursor phase which transforms into nanocrystalline, carbonated hydroxyapatite. While calcium phosphates have been under intense investigation, the exact steps during the crystallisation of spherical amorphous particle...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-06570-x

    authors: Lotsari A,Rajasekharan AK,Halvarsson M,Andersson M

    更新日期:2018-10-09 00:00:00

  • Publisher Correction: Orbital bistatic radar observations of asteroid Vesta by the Dawn mission.

    abstract::An incorrect version of the Supplementary Information was inadvertently published with this Article. The HTML has now been updated to include the correct version of the Supplementary Information. ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41467-017-01617-x

    authors: Palmer EM,Heggy E,Kofman W

    更新日期:2017-11-23 00:00:00

  • Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4.

    abstract::The small ubiquitin-like modifier (SUMO) can form polymeric chains that are important signals in cellular processes such as meiosis, genome maintenance and stress response. The SUMO-targeted ubiquitin ligase RNF4 engages with SUMO chains on linked substrates and catalyses their ubiquitination, which targets substrates...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms5217

    authors: Xu Y,Plechanovová A,Simpson P,Marchant J,Leidecker O,Kraatz S,Hay RT,Matthews SJ

    更新日期:2014-06-27 00:00:00

  • Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence.

    abstract::Methods for site-selective chemistry on proteins are in high demand for the synthesis of chemically modified biopharmaceuticals, as well as for applications in chemical biology, biosensors and more. Inadvertent N-terminal gluconoylation has been reported during expression of proteins with an N-terminal His tag. Here w...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-05695-3

    authors: Martos-Maldonado MC,Hjuler CT,Sørensen KK,Thygesen MB,Rasmussen JE,Villadsen K,Midtgaard SR,Kol S,Schoffelen S,Jensen KJ

    更新日期:2018-08-17 00:00:00

  • Highly atroposelective synthesis of nonbiaryl naphthalene-1,2-diamine N-C atropisomers through direct enantioselective C-H amination.

    abstract::Nonbiaryl N-C atropisomer is an important structural scaffold, which is present in natural products, medicines and chiral ligands. However the direct enantioselective C-H amination to access optically pure N-C atropisomer is still difficult and rare. Here we report a π-π interaction and dual H-bond concerted control s...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-10858-x

    authors: Bai HY,Tan FX,Liu TQ,Zhu GD,Tian JM,Ding TM,Chen ZM,Zhang SY

    更新日期:2019-07-11 00:00:00

  • Identification of carbon-encapsulated iron nanoparticles as active species in non-precious metal oxygen reduction catalysts.

    abstract::The widespread use of fuel cells is currently limited by the lack of efficient and cost-effective catalysts for the oxygen reduction reaction. Iron-based non-precious metal catalysts exhibit promising activity and stability, as an alternative to state-of-the-art platinum catalysts. However, the identity of the active ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms12582

    authors: Varnell JA,Tse EC,Schulz CE,Fister TT,Haasch RT,Timoshenko J,Frenkel AI,Gewirth AA

    更新日期:2016-08-19 00:00:00

  • Nanoparticles suppress fluid instabilities in the thermal drawing of ultralong nanowires.

    abstract::Ultra-long metal nanowires and their facile fabrication have been long sought after as they promise to offer substantial improvements of performance in numerous applications. However, ultra-long metal ultrafine/nanowires are beyond the capability of current manufacturing techniques, which impose limitations on their s...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-19796-5

    authors: Hwang I,Guan Z,Cao C,Tang W,Chui CO,Li X

    更新日期:2020-11-23 00:00:00

  • Longshot enables accurate variant calling in diploid genomes from single-molecule long read sequencing.

    abstract::Whole-genome sequencing using sequencing technologies such as Illumina enables the accurate detection of small-scale variants but provides limited information about haplotypes and variants in repetitive regions of the human genome. Single-molecule sequencing (SMS) technologies such as Pacific Biosciences and Oxford Na...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12493-y

    authors: Edge P,Bansal V

    更新日期:2019-10-11 00:00:00

  • VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.

    abstract::Mutant Huntingtin (mtHtt) causes neurodegeneration in Huntington's disease (HD) by evoking defects in the mitochondria, but the underlying mechanisms remains elusive. Our proteomic analysis identifies valosin-containing protein (VCP) as an mtHtt-binding protein on the mitochondria. Here we show that VCP is selectively...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms12646

    authors: Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X

    更新日期:2016-08-26 00:00:00

  • An intrinsic timer specifies distal structures of the vertebrate limb.

    abstract::How the positional values along the proximo-distal axis (stylopod-zeugopod-autopod) of the limb are specified is intensely debated. Early work suggested that cells intrinsically change their proximo-distal positional values by measuring time. Recently, however, it is suggested that instructive extrinsic signals from t...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms9108

    authors: Saiz-Lopez P,Chinnaiya K,Campa VM,Delgado I,Ros MA,Towers M

    更新日期:2015-09-18 00:00:00

  • Synthetic chimeric nucleases function for efficient genome editing.

    abstract::CRISPR-Cas systems have revolutionized genome editing across a broad range of biotechnological endeavors. Many CRISPR-Cas nucleases have been identified and engineered for improved capabilities. Given the modular structure of such enzymes, we hypothesized that engineering chimeric sequences would generate non-natural ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-13500-y

    authors: Liu RM,Liang LL,Freed E,Chang H,Oh E,Liu ZY,Garst A,Eckert CA,Gill RT

    更新日期:2019-12-04 00:00:00

  • RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis.

    abstract::Primary microcephaly (MCPH) is characterized by reduced brain size and intellectual disability. The exact pathophysiological mechanism underlying MCPH remains to be elucidated, but dysfunction of neuronal progenitors in the developing neocortex plays a major role. We identified a homozygous missense mutation (p.W155C)...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-19658-0

    authors: Farooq M,Lindbæk L,Krogh N,Doganli C,Keller C,Mönnich M,Gonçalves AB,Sakthivel S,Mang Y,Fatima A,Andersen VS,Hussain MS,Eiberg H,Hansen L,Kjaer KW,Gopalakrishnan J,Pedersen LB,Møllgård K,Nielsen H,Baig SM,Tommerup

    更新日期:2020-11-16 00:00:00

  • A programmable epidermal microfluidic valving system for wearable biofluid management and contextual biomarker analysis.

    abstract::Active biofluid management is central to the realization of wearable bioanalytical platforms that are poised to autonomously provide frequent, real-time, and accurate measures of biomarkers in epidermally-retrievable biofluids (e.g., sweat). Accordingly, here, a programmable epidermal microfluidic valving system is de...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18238-6

    authors: Lin H,Tan J,Zhu J,Lin S,Zhao Y,Yu W,Hojaiji H,Wang B,Yang S,Cheng X,Wang Z,Tang E,Yeung C,Emaminejad S

    更新日期:2020-09-02 00:00:00

  • Thorium-nitrogen multiple bonds provide evidence for pushing-from-below for early actinides.

    abstract::Although the chemistry of uranium-ligand multiple bonding is burgeoning, analogous complexes involving other actinides such as thorium remain rare and there are not yet any terminal thorium nitrides outside of cryogenic matrix isolation conditions. Here, we report evidence that reduction of a thorium-azide produces a ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12206-5

    authors: Du J,Alvarez-Lamsfus C,Wildman EP,Wooles AJ,Maron L,Liddle ST

    更新日期:2019-09-13 00:00:00

  • DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.

    abstract::Genetic heterogeneity between and within tumours is a major factor determining cancer progression and therapy response. Here we examined DNA sequence and DNA copy-number heterogeneity in colorectal cancer (CRC) by targeted high-depth sequencing of 100 most frequently altered genes. In 97 samples, with primary tumours ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms14093

    authors: Mamlouk S,Childs LH,Aust D,Heim D,Melching F,Oliveira C,Wolf T,Durek P,Schumacher D,Bläker H,von Winterfeld M,Gastl B,Möhr K,Menne A,Zeugner S,Redmer T,Lenze D,Tierling S,Möbs M,Weichert W,Folprecht G,Blanc E,

    更新日期:2017-01-25 00:00:00

  • Microbial carbon use efficiency predicted from genome-scale metabolic models.

    abstract::Respiration by soil bacteria and fungi is one of the largest fluxes of carbon (C) from the land surface. Although this flux is a direct product of microbial metabolism, controls over metabolism and their responses to global change are a major uncertainty in the global C cycle. Here, we explore an in silico approach to...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-11488-z

    authors: Saifuddin M,Bhatnagar JM,Segrè D,Finzi AC

    更新日期:2019-08-08 00:00:00

  • TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.

    abstract::Modulation of epigenetic patterns has promising efficacy for treating cancer. 5-Hydroxymethylated cytosine (5-hmC) is an epigenetic mark potentially important in cancer. Here we report that 5-hmC is an epigenetic hallmark of prostate cancer (PCa) progression. A member of the ten-eleven translocation (TET) proteins, wh...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms9219

    authors: Takayama K,Misawa A,Suzuki T,Takagi K,Hayashizaki Y,Fujimura T,Homma Y,Takahashi S,Urano T,Inoue S

    更新日期:2015-09-25 00:00:00

  • Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4 recognition and ADP-ribosylation.

    abstract::Tpt1 is an essential agent of fungal tRNA splicing that removes the 2'-PO4 at the splice junction generated by fungal tRNA ligase. Tpt1 catalyzes a unique two-step reaction whereby the 2'-PO4 attacks NAD+ to form an RNA-2'-phospho-ADP-ribosyl intermediate that undergoes transesterification to yield 2'-OH RNA and ADP-r...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-08211-9

    authors: Banerjee A,Munir A,Abdullahu L,Damha MJ,Goldgur Y,Shuman S

    更新日期:2019-01-15 00:00:00

  • Publisher Correction: Aerodynamic generation of electric fields in turbulence laden with charged inertial particles.

    abstract::The original version of this Article contained an error in the last sentence of the second paragraph of the 'Atmospheric rarefaction effects' section of the Results, which incorrectly read 'The other one emulates the rarefied, CO2-rich Martian atmosphere (μ♂ = 1.3 × 10-5 N s m-2) at 6.9 mbar and 210 K, which gives ρ♂ ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41467-018-04545-6

    authors: Di Renzo M,Urzay J

    更新日期:2018-05-21 00:00:00

  • Publisher Correction: The mutational impact of culturing human pluripotent and adult stem cells.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41467-020-17797-y

    authors: Kuijk E,Jager M,van der Roest B,Locati MD,Van Hoeck A,Korzelius J,Janssen R,Besselink N,Boymans S,van Boxtel R,Cuppen E

    更新日期:2020-08-04 00:00:00