Maternal serum sestrin 2 levels in preeclampsia and their relationship with the severity of the disease.

Abstract:

OBJECTIVE:To investigate sestrin 2 (SESN2) levels in preeclampsia (PE) cases and uncomplicated pregnancies. METHODS:Cross-sectional study including 26 pregnant women with PE, 24 with severe-PE, and 30 randomly selected healthy pregnant women. RESULTS:The mean arterial pressure, severe proteinuria, number of HELLP syndrome cases, and serum SESN2 levels in the severe PE group were significantly higher than those in the other groups (p < 0.001, p < 0.001, p = 0.006, and p = 0.004, respectively). Negative correlation was found between the birth interval (r = -.262, p = 0.019) and the SESN2 level. CONCLUSION:SESN2 seems to play a role in the pathophysiology of PE, especially in severe PE cases.

journal_name

Hypertens Pregnancy

authors

Tayyar AT,Tayyar A,Kozali S,Karakus R,Eser A,Abide Yayla C,Yalcin ET,Dag I,Eroglu M

doi

10.1080/10641955.2018.1540702

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

13-19

issue

1

eissn

1064-1955

issn

1525-6065

journal_volume

38

pub_type

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