Serum adiponectin levels in normal and hypertensive pregnancy.

Abstract:

OBJECTIVE:The aim of this study was to quantify adiponectin levels in women with normal and hypertensive pregnancies to determine whether there is an independent association, while controlling for body fat and insulin sensitivity. METHODS:A cross-sectional study was conducted in the following categories: 12 normotensive non-pregnant women, 10 normotensive, 12 gestational hypertensive, 13 essential hypertensive, and 12 preeclamptic women. All subjects underwent measurements of body fat by bio-impedance analysis and blood sampling. RESULTS:Percentage of body fat and insulin resistance were greater in all pregnant groups compared with non-pregnant women. Adiponectin concentrations were significantly lower in women with normal pregnancies (18.6 +/- 1.4 microg/mL, p = 0.02) compared with non-pregnant women (24.0 +/- 1.5 microg/mL). However, adiponectin levels were not significantly different among normal pregnancy, gestational hypertension (19.0 +/- 3.1 microg/mL), essential hypertension (24.0 +/- 3.7 microg/mL) and pre-eclampsia (22.4 +/- 2.5 microg/mL) groups. Adiponectin levels were inversely related to percent body fat and insulin resistance. When adiponectin levels were corrected for percent body fat and insulin resistance, no significant differences were seen among the study groups. CONCLUSIONS:Adiponectin levels are decreased in normal pregnancy, however this difference disappears when adiponectin levels are corrected for the pregnancy-related increases in body fat and insulin resistance. Adiponectin levels are not altered significantly in states of hypertension in pregnancy compared with normal pregnancy.

journal_name

Hypertens Pregnancy

authors

O'Sullivan AJ,Kriketos AD,Martin A,Brown MA

doi

10.1080/10641950600912976

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

193-203

issue

3

eissn

1064-1955

issn

1525-6065

pii

P600582R2L628651

journal_volume

25

pub_type

杂志文章
  • Relationship between nulliparity and preeclampsia may be explained by altered circulating soluble fms-like tyrosine kinase 1.

    abstract:OBJECTIVE:To test the hypothesis that the risk of preeclampsia in nulliparous women may be due to an anti-angiogenic state. METHODS:Maternal serum samples obtained in the third trimester from nulliparous (n = 86) and multiparous (n = 165) singleton uncomplicated pregnancies were analyzed for levels of angiogenic facto...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2013.858745

    authors: Bdolah Y,Elchalal U,Natanson-Yaron S,Yechiam H,Bdolah-Abram T,Greenfield C,Goldman-Wohl D,Milwidsky A,Rana S,Karumanchi SA,Yagel S,Hochner-Celnikier D

    更新日期:2014-05-01 00:00:00

  • Feto-maternal correlation of PTX3, sFlt-1 and PlGF in physiological and pre-eclamptic pregnancies.

    abstract:OBJECTIVE:PTX3, sFlt-1 and PlGF levels in maternal blood are altered in some obstetric diseases, such as preeclampsia (PE). Nonetheless, only few data on their expression in the fetal compartment have been reported so far. STUDY DESIGN:An observational study was performed by prospectively collecting maternal and fetal...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2014.903962

    authors: Algeri P,Ornaghi S,Bernasconi DP,Cappellini F,Signorini S,Brambilla P,Urban G,Vergani P

    更新日期:2014-08-01 00:00:00

  • Objective assessment of obstructive sleep apnea in normal pregnant and preeclamptic women.

    abstract:OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2018.1498879

    authors: Keshavarzi F,Mehdizadeh S,Khazaie H,Ghadami MR

    更新日期:2018-08-01 00:00:00

  • SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia.

    abstract:OBJECTIVE:We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS:In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase ch...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2016.1250904

    authors: Karakus S,Bagci B,Bagci G,Sancakdar E,Yildiz C,Akkar O,Cetin A

    更新日期:2017-05-01 00:00:00

  • Hypertensive disorders of pregnancy by oocyte donation pregnancy in Japanese women aged 40 years or older: a single-center retrospective cohort study.

    abstract::This study aimed to examine the incidence of hypertensive disorders of pregnancy (HDP) among Japanese women with oocyte donation pregnancy (ODP) aged 40 years or older and estimate whether the women with ODP were more likely to develop HDP than those with autologous oocyte pregnancy (AOP) and spontaneous pregnancy (SP...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2020.1861461

    authors: Gekka Y,Adachi T,Oi R,Nakayama S,Kawana Y,Takeda Y,Nomura S,Ozaki A,Tanimoto T,Sakamoto H,Yamashita T

    更新日期:2021-02-01 00:00:00

  • Second pregnancy outcomes following preeclampsia in a first pregnancy.

    abstract:OBJECTIVES:We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS:One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1081/PRG-200059869

    authors: Lain KY,Krohn MA,Roberts JM

    更新日期:2005-01-01 00:00:00

  • Antepartum middle mean cerebral blood flow velocity correlation with maternal hemodynamics.

    abstract:OBJECTIVE:To determine the correlation between simultaneous assessment of maternal middle cerebral blood flow velocity with the other maternal hemodynamic factors of cardiac output and mean arterial pressure. STUDY DESIGN:Eight normotensive patients were assessed. Maternal cerebral blood flow velocity was assessed usi...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641959909016200

    authors: Williams KP,Wilson S

    更新日期:1999-01-01 00:00:00

  • Cytokine production by monocytes, NK cells, and lymphocytes is different in preeclamptic patients as compared with normal pregnant women.

    abstract:OBJECTIVE:To measure cytokine production in ex vivo stimulated leukocyte populations of women with normal pregnancy and those with preeclampsia. METHODS:Whole blood from preeclamptic and normal pregnant women was stimulated with LPS or PMA/Ca-ionophore. The percentages of IFN gamma and IL-2, 4, and 10 producing lympho...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641950701885006

    authors: van Nieuwenhoven AL,Moes H,Heineman MJ,Santema J,Faas MM

    更新日期:2008-01-01 00:00:00

  • Fibrinolysis parameters in Sudanese women with severe preeclampsia.

    abstract:BACKGROUND:Although preeclampsia remains a major cause of maternal and fetal morbidity and mortality, its pathogenesis is not fully understood. Coagulation and fibrinolysis changes were suggested to have a role in the pathogenesis of preeclampsia. OBJECTIVES:A case-control study was conducted in Medani Hospital, Sudan...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2016.1211676

    authors: Elzein HO,Muddathir AR,Rida M,Rayis DA,Elhassan EM,Adam I

    更新日期:2016-11-01 00:00:00

  • Placental maturity, hypertensive disorders of pregnancy and birth weight.

    abstract:OBJECTIVES:To compare maturity of placentas from women with hypertensive disorders with those from normotensive pregnancies and to determine the relationship between placental maturity (PM) and the diagnosis of small-for-gestational-age (SGA) in the newborns. MATERIALS AND METHODS:We examined placental stained specime...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2013.842583

    authors: Ruiz-Quiñonez G,Reza-López SA,Chávez-Corral DV,Sánchez-Ramírez B,Leal-Berumen I,Levario-Carrillo M

    更新日期:2014-05-01 00:00:00

  • Treatment of severe hypertension during pregnancy: we still do not know what the best option is.

    abstract::Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章,评审

    doi:10.1080/10641955.2019.1708383

    authors: Wertaschnigg D,Wang R,Reddy M,Costa FDS,Mol BWJ,Rolnik DL

    更新日期:2020-02-01 00:00:00

  • Hemodynamic adaptation during pregnancy in chronic hypertension.

    abstract:OBJECTIVE:To assess hemodynamic and NT-proANP changes in women with chronic hypertension during pregnancy. METHODS:Stroke volume index (SI), heart rate (HR), cardiac output index (CI), systemic vascular resistance index (SVRI), pulse wave velocity (PWV), and left cardiac work index (LCWI) were measured using whole-bod...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641950701436016

    authors: Tihtonen K,Kööbi T,Huhtala H,Uotila J

    更新日期:2007-01-01 00:00:00

  • Patterns of pregnancy-related hypertension in black and white women.

    abstract:OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641950500281134

    authors: Bryant AS,Seely EW,Cohen A,Lieberman E

    更新日期:2005-01-01 00:00:00

  • Predicting transformation from gestational hypertension to preeclampsia in clinical practice: a possible role for 24 hour ambulatory blood pressure monitoring.

    abstract:OBJECTIVE:To identify parameters that may assist clinicians in predicting which women will develop preeclampsia (PE) after initially presenting with gestational hypertension (GH). METHODS:118 women were recruited to the study with GH or PE. They were divided into three groups based on their diagnosis at delivery- (1) ...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641950601147952

    authors: Davis GK,Mackenzie C,Brown MA,Homer CS,Holt J,McHugh L,Mangos G

    更新日期:2007-01-01 00:00:00

  • Do racial differences exist in the association between pregnancy-induced hypertension and breast cancer risk?

    abstract:BACKGROUND:Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we de...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2016.1258411

    authors: Lin LT,Hu LY,Tang PL,Tsui KH,Cheng JT,Huang WC,Chang HT

    更新日期:2017-05-01 00:00:00

  • Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats.

    abstract::Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2019.1647232

    authors: Igonina TN,Ragaeva DS,Petrova OM,Rozkova IN,Brusentsev EY,Amstislavsky SY

    更新日期:2019-11-01 00:00:00

  • Maternal Serum Resistin Is Reduced in First Trimester Preeclampsia Pregnancies and Is a Marker of Clinical Severity.

    abstract:OBJECTIVE:To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE). METHODS:A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and materna...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2014.913615

    authors: Christiansen M,Hedley PL,Placing S,Wøjdemann KR,Carlsen AL,Jørgensen JM,Gjerris AC,Shalmi AC,Rode L,Sundberg K,Tabor A

    更新日期:2015-11-01 00:00:00

  • Mechanisms of endothelium-dependent relaxation in myometrial resistance vessels and their alteration in preeclampsia.

    abstract:OBJECTIVE:To investigate the importance of prostacyclin and nitric oxide synthesis in endothelium-dependent relaxation in myometrial resistance vessels, and to test the hypothesis that a deficiency in nitric oxide synthesis contributes to the known alterations in endothelial function in preeclampsia. METHODS:Thirty-si...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641959909009611

    authors: Ashworth JR,Baker PN,Warren AY,Johnson IR

    更新日期:1999-01-01 00:00:00

  • Changes in endothelial function, arterial stiffness and blood pressure in pregnant women after consumption of high-flavanol and high-theobromine chocolate: a double blind randomized clinical trial.

    abstract:OBJECTIVES:The aim of this 2-group, parallel, double blind single-centre RCT was to evaluate the acute and chronic impacts of high flavanol high theobromine (HFHT) chocolate consumption on endothelial function, arterial stiffness and blood pressure (BP) in women at risk of preeclampsia. METHODS:131 pregnant women cons...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/10641955.2018.1446977

    authors: Babar A,Bujold E,Leblanc V,Lavoie-Lebel É,Paquette J,Bazinet L,Lemieux S,Marc I,Abdous B,Dodin S

    更新日期:2018-05-01 00:00:00

  • Is gestational hypertension associated with affective temperaments?

    abstract::Objective: Gestational hypertension (GH) is an important pregnancy complication. Sparse studies have shown a correlation between this complication and psychological disorders in patients. In this study, we aimed to assess the possible association between affective temperaments and GH.Methods: This cross-sectional stud...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2020.1749279

    authors: Rezaei Ardani A,Tara F,Naghizadeh Kashani S,Hatami SB,Emadzadeh M,Nahidi M

    更新日期:2020-05-01 00:00:00

  • Neurodevelopmental and cognitive assessment of children born growth restricted to mothers with and without preeclampsia.

    abstract::We examined neurological and intellectual outcome of growth-restricted newborns of pregnancies complicated with preeclampsia and without preeclampsia. Seventy-five consecutive growth restricted newborns (<5th percentile) were prospectively followed up at 6 months' intervals. Newborns with major congenital malformation...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1081/PRG-120016791

    authors: Many A,Fattal A,Leitner Y,Kupferminc MJ,Harel S,Jaffa A

    更新日期:2003-01-01 00:00:00

  • Ethnic differences in the monthly variation of preeclampsia among Bedouin and Jewish parturients in the Negev.

    abstract:OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of ...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641950902968692

    authors: Shental O,Friger M,Sheiner E

    更新日期:2010-01-01 00:00:00

  • Connexin expression is not altered in omental resistance vessels from women with preeclampsia.

    abstract:OBJECTIVE:To compare connexin expression in omental resistance arteries from preeclamptic women and normal gravidas. METHODS:Small arteries (approximately 200-400 microm i.d.) were dissected from omental fat biopsies, taken at cesarean delivery from normotensive and preeclamptic women. Vessels were frozen and homogeni...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1081/PRG-100104178

    authors: Umans JG,Lindheimer MD,Hack B,Davidson-Garcia CA

    更新日期:2001-01-01 00:00:00

  • Hypertensive disorders during monozygotic and dizygotic twin gestations: A population-based study.

    abstract:OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2016.1197936

    authors: Lučovnik M,Blickstein I,Lasič M,Fabjan-Vodušek V,Bržan-Simenc G,Verdenik I,Tul N

    更新日期:2016-11-01 00:00:00

  • Heat shock protein 70 is not increased in women with severe preeclampsia.

    abstract:OBJECTIVE:The purpose of this study is to determine if heat shock protein 70 (Hsp 70), a marker of cellular stress, is elevated in pregnancies complicated by severe preeclampsia. METHODS:Maternal blood was collected from women with severe preeclampsia (n=47) matched for delivery gestational age to normotensive pregnan...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1081/PRG-120004767

    authors: Livingston JC,Ahokas R,Haddad B,Sibai BM,Awaads R

    更新日期:2002-01-01 00:00:00

  • Elevated serum-soluble Fas in preeclampsia: correlation with clinical, laboratory, and Doppler parameters.

    abstract:OBJECTIVES:(i) To compare the levels of soluble Fas (sFas) in the sera of patients with variable degrees of preeclampsia and in healthy gravidas; and (ii) to correlate sFas with clinical, laboratory, and Doppler parameters in preeclampsia. METHODS:Fifty patients with mild preeclampsia, 50 patients with severe preeclam...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2010.544804

    authors: El-Sherbiny W,Soliman A,El-Mazny A

    更新日期:2011-01-01 00:00:00

  • Management of severe pregnancy-induced hypertension after 34 weeks of gestation: A prospective study to reduce the rate of cesarean section.

    abstract:OBJECTIVE:The aim of this study was to reduce the rate of cesarean section (CS) in severe pregnancy-induced hypertension (PIH) by introducing a set of indicative criteria for CS. METHODS:Labor induction was attempted in Japanese patients (n = 41) with severe PIH after 34 weeks of gestation. Vital signs and symptoms th...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.3109/10641955.2015.1115061

    authors: Shibata T,Nakago S,Kato H,Tokuda H,Matsuki R,Kotsuji F

    更新日期:2016-01-01 00:00:00

  • Preventing preeclampsia and its fetal complications with low-dose aspirin in East Asians and non-East Asians:A systematic review and meta-analysis.

    abstract:BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章,meta分析,评审

    doi:10.1080/10641955.2016.1178772

    authors: Gan J,He H,Qi H

    更新日期:2016-08-01 00:00:00

  • Maternal serum Chlamydia pneumoniae antibodies and CRP levels in women with preeclampsia and gestational hypertension.

    abstract:OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641950701885188

    authors: Karinen L,Leinonen M,Bloigu A,Paldanius M,Koskela P,Saikku P,Hartikainen AL,Jarvelin MR,Pouta A

    更新日期:2008-01-01 00:00:00

  • Maternal levels of growth differentiation factor-15 in patients with preeclampsia.

    abstract:OBJECTIVE:Growth differentiation factor-15 (GDF-15) is a stress-induced cytokine and related to the prognosis of cardiovascular diseases. Our purpose is to measure the maternal levels of GDF-15 in patients with early-onset preeclampsia (EOPE) and late-onset preeclampsia (LOPE). METHODS:This cross-sectional study was c...

    journal_title:Hypertension in pregnancy

    pub_type: 杂志文章

    doi:10.1080/10641955.2018.1524477

    authors: Temel Yuksel I,Mathyk BA,Aslan Cetin B,Turhan U,Okumus ZG,Yetkin Yildirim G,Acar DK

    更新日期:2018-11-01 00:00:00