Abstract:
OBJECTIVE:To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE). METHODS:A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and maternal age. Samples were taken in gestational weeks 10+0-13+6. RESULTS:There was a negative correlation between resistin and clinical severity of PE, but no correlation with IS, TNF-α, body mass index, birth weight and pregnancy length. CONCLUSIONS:Resistin is reduced in first trimester of PE pregnancies, particularly in severe PE. Inflammation and IS cannot explain this phenomenon.
journal_name
Hypertens Pregnancyjournal_title
Hypertension in pregnancyauthors
Christiansen M,Hedley PL,Placing S,Wøjdemann KR,Carlsen AL,Jørgensen JM,Gjerris AC,Shalmi AC,Rode L,Sundberg K,Tabor Adoi
10.3109/10641955.2014.913615subject
Has Abstractpub_date
2015-11-01 00:00:00pages
422-433issue
4eissn
1064-1955issn
1525-6065journal_volume
34pub_type
杂志文章abstract:BACKGROUND:Hypertension that develops after 20 gestational weeks and is defined as pregnancy-induced hypertension (PIH). The main cause of PIH is vasoconstriction and the thickening of vascular media, which decreases vascular capacity and increases peripheral resistance. One of the theories postulated to explain this p...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950600601835
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To investigate the importance of prostacyclin and nitric oxide synthesis in endothelium-dependent relaxation in myometrial resistance vessels, and to test the hypothesis that a deficiency in nitric oxide synthesis contributes to the known alterations in endothelial function in preeclampsia. METHODS:Thirty-si...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641959909009611
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:The aim of this 2-group, parallel, double blind single-centre RCT was to evaluate the acute and chronic impacts of high flavanol high theobromine (HFHT) chocolate consumption on endothelial function, arterial stiffness and blood pressure (BP) in women at risk of preeclampsia. METHODS:131 pregnant women cons...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,随机对照试验
doi:10.1080/10641955.2018.1446977
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Escherichia coli O157:H7 is a common cause of bacterial gastroenteritis and may increase the risk of hypertension. We studied the risk of hypertension in pregnancy following a large E. coli O157:H7 outbreak that occurred in Walkerton, Canada, in the year 2000. METHODS:We linked data collected from Walkerton...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.810238
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To provide long-term follow-up data on women with a history of hemolysis, elevated liver enzymes, and low platelets [(H)ELLP] syndrome regarding the risk of recurrence in subsequent pregnancies and disease in later life. METHODS:All women admitted to the Academic Medical Centre between January 1984 and Janua...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-100104168
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:(i) To compare the levels of soluble Fas (sFas) in the sera of patients with variable degrees of preeclampsia and in healthy gravidas; and (ii) to correlate sFas with clinical, laboratory, and Doppler parameters in preeclampsia. METHODS:Fifty patients with mild preeclampsia, 50 patients with severe preeclam...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2010.544804
更新日期:2011-01-01 00:00:00
abstract::We examined neurological and intellectual outcome of growth-restricted newborns of pregnancies complicated with preeclampsia and without preeclampsia. Seventy-five consecutive growth restricted newborns (<5th percentile) were prospectively followed up at 6 months' intervals. Newborns with major congenital malformation...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-120016791
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Amino-terminal pro-brain natriuretic peptide (NT-proBNP) is synthesized in cardiac ventricles in response to volume expansion. This study evaluated NT-proBNP levels to determine the clinical correlation with the severity of hypertensive disorders complicating pregnancy. METHODS:NT-proBNP levels of 95 pregnan...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950903115046
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950500281134
更新日期:2005-01-01 00:00:00
abstract::Objective: Gestational hypertension (GH) is an important pregnancy complication. Sparse studies have shown a correlation between this complication and psychological disorders in patients. In this study, we aimed to assess the possible association between affective temperaments and GH.Methods: This cross-sectional stud...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1749279
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Chymase, a chymotrypsin-like protease, is a non-ACE angiotensin II (Ang II) generating enzyme. We determined if maternal chymotrypsin-like protease/chymase activity was increased in women with preeclampsia (PE). METHODS:Maternal plasma was extracted from venous blood of healthy nonpregnant women, women with ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950802001842
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS:One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-200059869
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.877925
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To determine whether delivery mode influences placental chorionic plate arterial and venous vascular reactivity. METHODS:Normal term placentas were obtained after vaginal delivery or cesarean section. Chorionic plate arterial and venous function was assessed by wire myography. RESULTS:Sodium nitroprusside-i...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10601330701274824
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To elicit women's personal understanding of future cardiovascular risk, following a pregnancy complicated by preeclampsia, and to identify the postnatal needs of these women. METHODS:Semi-structured interviews with 12 women with a recent history of preeclampsia who had attended a postnatal follow-up clinic. ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2012.704108
更新日期:2013-01-01 00:00:00
abstract::The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of pregnancy were compared with naturally conceived controls. Surgery dur...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1762894
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To determine the relationship between the cancer antigen-125 (CA-125) and C-reactive protein (CRP) with preeclampsia and eclampsia. METHODS:The study group included 54 preeclamptic/eclamptic women, and 56 healthy pregnant women served as the control group. Mean arterial pressure (MAP) and albumin levels were...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950802601187
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE(S):We tested the hypothesis that twin pregnancies would lead to increased maternal plasma homocysteine. We further hypothesized that twin pregnancies complicated by preeclampsia would have increased plasma homocysteine compared to twin pregnancies without preeclampsia and normal singleton pregnancies. METHOD...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-45774
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950902968692
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to determine if heat shock protein 70 (Hsp 70), a marker of cellular stress, is elevated in pregnancies complicated by severe preeclampsia. METHODS:Maternal blood was collected from women with severe preeclampsia (n=47) matched for delivery gestational age to normotensive pregnan...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-120004767
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVES:To compare maturity of placentas from women with hypertensive disorders with those from normotensive pregnancies and to determine the relationship between placental maturity (PM) and the diagnosis of small-for-gestational-age (SGA) in the newborns. MATERIALS AND METHODS:We examined placental stained specime...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.842583
更新日期:2014-05-01 00:00:00
abstract::The pathophysiology of preeclampsia (PET) implicates an inflammatory dysfunction. This study profiled this host response by challenging whole blood with lipopolysaccharide. Multiplex immunoassays determined interleukin (IL)-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12(p70), IL-13, IL-17, granulocyte/granulo...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701826067
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. METHODS:A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delive...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2010.506231
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we de...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1258411
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701548240
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1197936
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To investigate the intraplatelet cyclic guanosine-3',5'-monophosphate (cGMP) levels during normal pregnancy and preeclampsia. STUDY DESIGN:Pregnant women (n = 15), women with preeclampsia (n = 15), and nonpregnant, normotensive women (n = 15) were included. Intraplatelet cyclic guanosine-3',5'-monophosphate ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-200030860
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701885188
更新日期:2008-01-01 00:00:00
abstract::Objectives: Establishment of association between: (a) Val158Met COMT (G1947A) polymorphism and preeclampsia; (b) cytokines gene expression and COMT genotypes. Methods: 50 preeclampsia and 50 healthy pregnant women were enrolled. COMT genotyping was done by PCR/RFLP. TNF-α, IL-1β, and IL-6 mRNA levels were determined b...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1843663
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,meta分析,评审
doi:10.1080/10641955.2016.1178772
更新日期:2016-08-01 00:00:00