Elevated plasma chymotrypsin-like protease (chymase) activity in women with preeclampsia.

abstract：OBJECTIVE:To compare connexin expression in omental resistance arteries from preeclamptic women and normal gravidas. METHODS:Small arteries (approximately 200-400 microm i.d.) were dissected from omental fat biopsies, taken at cesarean delivery from normotensive and preeclamptic women. Vessels were frozen and homogeni...

journal_title：Hypertension in pregnancy

authors： Umans JG,Lindheimer MD,Hack B,Davidson-Garcia CA

更新日期：2001-01-01 00:00:00

abstract：:The pathophysiology of preeclampsia (PET) implicates an inflammatory dysfunction. This study profiled this host response by challenging whole blood with lipopolysaccharide. Multiplex immunoassays determined interleukin (IL)-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12(p70), IL-13, IL-17, granulocyte/granulo...

journal_title：Hypertension in pregnancy

authors： Brewster JA,Orsi NM,Gopichandran N,Ekbote UV,Cadogan E,Walker JJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Escherichia coli O157:H7 is a common cause of bacterial gastroenteritis and may increase the risk of hypertension. We studied the risk of hypertension in pregnancy following a large E. coli O157:H7 outbreak that occurred in Walkerton, Canada, in the year 2000. METHODS:We linked data collected from Walkerton...

journal_title：Hypertension in pregnancy

authors： Nevis IF,Sontrop JM,Clark WF,Huang A,McDonald S,Thabane L,Moist L,Macnab JJ,Suri R,Garg AX

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to determine if heat shock protein 70 (Hsp 70), a marker of cellular stress, is elevated in pregnancies complicated by severe preeclampsia. METHODS:Maternal blood was collected from women with severe preeclampsia (n=47) matched for delivery gestational age to normotensive pregnan...

journal_title：Hypertension in pregnancy

authors： Livingston JC,Ahokas R,Haddad B,Sibai BM,Awaads R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To report a case of cardiac arrhythmia related to a low dose of endovenous lanatoside C. CASE REPORT:A 23-year-old pregnant woman with mitral regurgitation complicated with preeclampsia and pulmonary edema presented 2 episodes of atrial tachycardia induced by a intravenous digitalis (2 mg, IV and 1 mg, IV, r...

journal_title：Hypertension in pregnancy

authors： Roscani MG,Zanati SG,Magalhães CG,Borges VT,Matsubara BB

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. METHODS:Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every...

journal_title：Hypertension in pregnancy

authors： Samangaya RA,Mires G,Shennan A,Skillern L,Howe D,McLeod A,Baker PN

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:Leukocytes are activated in women with preeclampsia, but the class of leukocytes that infiltrates the maternal vasculature and, therefore, is most likely to cause vascular dysfunction is not known. METHODS:Subcutaneous fat biopsies were obtained at Cesarean section or abdominal surgery from 7 normal non-preg...

journal_title：Hypertension in pregnancy

authors： Cadden KA,Walsh SW

更新日期：2008-01-01 00:00:00

abstract：:Preeclampsia and intrauterine growth restriction are both characterized by placental malfunction. The pathological processes of abnormal trophoblast invasion, partial absence of maternal spiral artery modification, increased apoptosis of trophoblast cells, and placental ischemia are all associated with the release of ...

journal_title：Hypertension in pregnancy

authors： Tjoa ML,Oudejans CB,van Vugt JM,Blankenstein MA,van Wijk IJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Pre-eclampsia is associated with significant maternal and neonatal complications, and delivery is often expedited to minimise complications. For randomised trials evaluating interventions in women with late-onset (>34 weeks) mild to moderate pre-eclampsia, no single outcome has been identified to be the most ...

journal_title：Hypertension in pregnancy

authors： Fong F,Rogozinska E,Allotey J,Kempley S,Shah DK,Thangaratinam S

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE). METHODS:A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and materna...

journal_title：Hypertension in pregnancy

authors： Christiansen M,Hedley PL,Placing S,Wøjdemann KR,Carlsen AL,Jørgensen JM,Gjerris AC,Shalmi AC,Rode L,Sundberg K,Tabor A

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To provide long-term follow-up data on women with a history of hemolysis, elevated liver enzymes, and low platelets [(H)ELLP] syndrome regarding the risk of recurrence in subsequent pregnancies and disease in later life. METHODS:All women admitted to the Academic Medical Centre between January 1984 and Janua...

journal_title：Hypertension in pregnancy

authors： van Pampus MG,Wolf H,Mayruhu G,Treffers PE,Bleker OP

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To describe the incidence and obstetric and perinatal outcomes in primigravid Black South Africans with hypertensive disorders of pregnancy (HDP). METHOD:All primigravidae who booked for antenatal care were followed up until hospital discharge. Relevant clinical and demographic data were collected in structu...

journal_title：Hypertension in pregnancy

authors： Moodley J,Onyangunga OA,Maharaj NR

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the levels of serum lipoproteins in women with pregnancy-induced hypertension and compare it with the corresponding levels in pregnant women having normal blood pressure. METHOD:This cross-sectional study was conducted in the three tertiary care hospitals of Peshawar, North West Frontier Provinc...

journal_title：Hypertension in pregnancy

authors： Jan MR,Nazli R,Shah J,Akhtar T

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This study investigated endothelin-1 (ET-1) production induced by vascular endothelial growth factor (VEGF) in two different vascular wall cell types. METHODS:We analyzed the effect of endothelin-converting enzyme-1 (ECE-1) inhibitor and tissue inhibitors of matrix metalloproteinase-2 (TIMP-2) on VEGF-induce...

journal_title：Hypertension in pregnancy

authors： Seol HJ,Oh MJ,Kim HJ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The angiogenic-antiangiogenic imbalance evident in preeclampsia (PE) may be used as a predictive tool to identify women likely to develop the clinical features in early pregnancy. METHOD:This retrospective study examined normotensive pregnant (n = 38) and preeclamptic (n = 38) HIV-infected and uninfected wom...

journal_title：Hypertension in pregnancy

authors： Thakoordeen S,Moodley J,Naicker T

更新日期：2017-05-01 00:00:00

abstract：:Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...

journal_title：Hypertension in pregnancy

authors： Wertaschnigg D,Wang R,Reddy M,Costa FDS,Mol BWJ,Rolnik DL

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Assess the actual rate of eclampsia in Sweden, describe the clinical picture of the disease and the maternal and perinatal outcomes. METHODS:Analysis of data regarding incidence of eclampsia registered in the Swedish Medical Birth Register 1991-1992. The records of all the cases with the diagnosis of eclamps...

journal_title：Hypertension in pregnancy

authors： Kullberg G,Lindeberg S,Hanson U

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...

journal_title：Hypertension in pregnancy

authors： Gabbay A,Tzur T,Weintraub AY,Shoham-Vardi I,Sergienko R,Sheiner E

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies. METHODS:We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnanc...

journal_title：Hypertension in pregnancy

authors： Suzuki S,Yoneyama Y,Sawa R,Shin S,Araki T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To investigate the importance of prostacyclin and nitric oxide synthesis in endothelium-dependent relaxation in myometrial resistance vessels, and to test the hypothesis that a deficiency in nitric oxide synthesis contributes to the known alterations in endothelial function in preeclampsia. METHODS:Thirty-si...

journal_title：Hypertension in pregnancy

authors： Ashworth JR,Baker PN,Warren AY,Johnson IR

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Growth differentiation factor-15 (GDF-15) is a stress-induced cytokine and related to the prognosis of cardiovascular diseases. Our purpose is to measure the maternal levels of GDF-15 in patients with early-onset preeclampsia (EOPE) and late-onset preeclampsia (LOPE). METHODS:This cross-sectional study was c...

journal_title：Hypertension in pregnancy

authors： Temel Yuksel I,Mathyk BA,Aslan Cetin B,Turhan U,Okumus ZG,Yetkin Yildirim G,Acar DK

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS:In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase ch...

journal_title：Hypertension in pregnancy

authors： Karakus S,Bagci B,Bagci G,Sancakdar E,Yildiz C,Akkar O,Cetin A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To investigate the intraplatelet cyclic guanosine-3',5'-monophosphate (cGMP) levels during normal pregnancy and preeclampsia. STUDY DESIGN:Pregnant women (n = 15), women with preeclampsia (n = 15), and nonpregnant, normotensive women (n = 15) were included. Intraplatelet cyclic guanosine-3',5'-monophosphate ...

journal_title：Hypertension in pregnancy

authors： Teran E,Escudero C,Vivero S,Enriquez A,Calle A

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:The aim of this 2-group, parallel, double blind single-centre RCT was to evaluate the acute and chronic impacts of high flavanol high theobromine (HFHT) chocolate consumption on endothelial function, arterial stiffness and blood pressure (BP) in women at risk of preeclampsia. METHODS:131 pregnant women cons...

journal_title：Hypertension in pregnancy

authors： Babar A,Bujold E,Leblanc V,Lavoie-Lebel É,Paquette J,Bazinet L,Lemieux S,Marc I,Abdous B,Dodin S

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Caesarean section (CS) is one of the most frequently performed surgical procedures worldwide. Surgical variants include closure and non-closure of the peritoneum: in case of non-suturing the visceral peritoneum (VP), abnormal fluid collections such as blood clots may lead to formation of a hematoperitoneum...

journal_title：Hypertension in pregnancy

authors： Malvasi A,Tinelli A,Hudelist G,Vergara D,Martignago R,Tinelli R

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To evaluate Protein/Creatinine ratio on random urine samples for prediction of proteinuria in preeclampsia. MATERIALS AND METHODS:This study was performed on 150 pregnant women who were hospitalized as preeclampsia in Ghaem Hospital during 2006. At first, a 24-hours urine sample was collected for each patien...

journal_title：Hypertension in pregnancy

authors： Roudsari FV,Ayati S,Ayatollahi H,Shakeri MT

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:DNA methylation is an important epigenetic regulator of gene transcription, and is involved in many diseases, which has been researched recently. In this study, we aimed to investigate DNA methylation and gene expression in preeclampsia placenta. Preeclampsia has been observed in patients with molar pregnancy...

journal_title：Hypertension in pregnancy

authors： Xuan J,Jing Z,Yuanfang Z,Xiaoju H,Pei L,Guiyin J,Yu Z

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...

journal_title：Hypertension in pregnancy

authors： Keshavarzi F,Mehdizadeh S,Khazaie H,Ghadami MR

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...

journal_title：Hypertension in pregnancy

authors： Gan J,He H,Qi H

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...

journal_title：Hypertension in pregnancy

authors： Lučovnik M,Blickstein I,Lasič M,Fabjan-Vodušek V,Bržan-Simenc G,Verdenik I,Tul N

更新日期：2016-11-01 00:00:00