Abstract:
OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of patients with and without preeclampsia was performed. The study included all deliveries between and including 1988 and 2007. For each month, the percentage of births complicated by preeclampsia was calculated. The relative risks of preeclampsia by month of delivery were estimated as odds ratios, using the month of August as the reference category. RESULTS:During the study period, 203,461 deliveries took place, of which 8,421 (4.1%) were complicated with preeclampsia (either mild or severe). Significantly higher incidence of preeclampsia was demonstrated in the Jewish population: 4.7% (n = 4,783 deliveries) versus 3.6% in the Bedouin population (n = 3,683), (p < 0.001). A similar U shaped trend in the incidence of preeclampsia was noted in both populations: the incidence was highest in the winter months and reached its nadir in August, with subsequent increase through the fall months (p < 0.001). Using August as the reference month, odds ratios were 1.32 (95% CI 1.19-1.48) for January, 1.38 (95% CI 1.24-1.54) for February and 1.33 (95% CI 1.19-1.48) for March. Time series analysis demonstrated a difference in the behavior of the 2 populations. Whereas the Jewish population had demonstrated a Gregorian-month cycle, the Bedouin population had demonstrated a lunar-month cycle. CONCLUSION:Preeclampsia is significantly more common in the Jewish population. However, both populations demonstrate the same seasonal pattern, with higher incidence of preeclampsia in the winter months. Our findings suggest that climate and environmental exposure may have an important role in the pathophysiology of preeclampsia.
journal_name
Hypertens Pregnancyjournal_title
Hypertension in pregnancyauthors
Shental O,Friger M,Sheiner Edoi
10.3109/10641950902968692subject
Has Abstractpub_date
2010-01-01 00:00:00pages
342-9issue
3eissn
1064-1955issn
1525-6065journal_volume
29pub_type
杂志文章abstract:OBJECTIVE:To evaluate Protein/Creatinine ratio on random urine samples for prediction of proteinuria in preeclampsia. MATERIALS AND METHODS:This study was performed on 150 pregnant women who were hospitalized as preeclampsia in Ghaem Hospital during 2006. At first, a 24-hours urine sample was collected for each patien...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2010.507838
更新日期:2012-01-01 00:00:00
abstract::Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,评审
doi:10.1080/10641955.2019.1708383
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS:One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-200059869
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the levels of serum lipoproteins in women with pregnancy-induced hypertension and compare it with the corresponding levels in pregnant women having normal blood pressure. METHOD:This cross-sectional study was conducted in the three tertiary care hospitals of Peshawar, North West Frontier Provinc...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2010.507843
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To investigate sestrin 2 (SESN2) levels in preeclampsia (PE) cases and uncomplicated pregnancies. METHODS:Cross-sectional study including 26 pregnant women with PE, 24 with severe-PE, and 30 randomly selected healthy pregnant women. RESULTS:The mean arterial pressure, severe proteinuria, number of HELLP syn...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2018.1540702
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950500281134
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To determine the relationship between the cancer antigen-125 (CA-125) and C-reactive protein (CRP) with preeclampsia and eclampsia. METHODS:The study group included 54 preeclamptic/eclamptic women, and 56 healthy pregnant women served as the control group. Mean arterial pressure (MAP) and albumin levels were...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950802601187
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS:In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase ch...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1250904
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To report a case of cardiac arrhythmia related to a low dose of endovenous lanatoside C. CASE REPORT:A 23-year-old pregnant woman with mitral regurgitation complicated with preeclampsia and pulmonary edema presented 2 episodes of atrial tachycardia induced by a intravenous digitalis (2 mg, IV and 1 mg, IV, r...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950902928571
更新日期:2010-01-01 00:00:00
abstract::Preeclampsia and intrauterine growth restriction are both characterized by placental malfunction. The pathological processes of abnormal trophoblast invasion, partial absence of maternal spiral artery modification, increased apoptosis of trophoblast cells, and placental ischemia are all associated with the release of ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,评审
doi:10.1081/PRG-120028292
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:Amino-terminal pro-brain natriuretic peptide (NT-proBNP) is synthesized in cardiac ventricles in response to volume expansion. This study evaluated NT-proBNP levels to determine the clinical correlation with the severity of hypertensive disorders complicating pregnancy. METHODS:NT-proBNP levels of 95 pregnan...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950903115046
更新日期:2011-01-01 00:00:00
abstract::The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of pregnancy were compared with naturally conceived controls. Surgery dur...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1762894
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:There is evidence of altered vascular endothelial function in women with preeclampsia as well as in the endothelial cells from umbilical vessels of preeclamptic pregnancies. Matrix metalloproteinase (MMP)-2 is elevated in the plasma of preeclamptic women and is a mediator of vascular reactivity; however, whe...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-120028281
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,meta分析,评审
doi:10.1080/10641955.2016.1178772
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:The diagnostic value of affinity-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis to distinguish preeclampsia (PE) from matched controls was tested in a multicenter setting. METHODS:Serum samples of preeclamptic (n = 60) and healthy pregnant women (n = 66) from four...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,多中心研究
doi:10.3109/10641955.2011.640375
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701885188
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To investigate the intraplatelet cyclic guanosine-3',5'-monophosphate (cGMP) levels during normal pregnancy and preeclampsia. STUDY DESIGN:Pregnant women (n = 15), women with preeclampsia (n = 15), and nonpregnant, normotensive women (n = 15) were included. Intraplatelet cyclic guanosine-3',5'-monophosphate ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-200030860
更新日期:2004-01-01 00:00:00
abstract::Objective: Gestational hypertension (GH) is an important pregnancy complication. Sparse studies have shown a correlation between this complication and psychological disorders in patients. In this study, we aimed to assess the possible association between affective temperaments and GH.Methods: This cross-sectional stud...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1749279
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Some evidence indicated the role of nutrition in the development of hypertensive disorders of pregnancy. METHODS:This case-control study was conducted on 113 women with gestational hypertension and 150 healthy pregnant women referred to Shahid Akbarabadi Hospital in Tehran. A demographic questionnaire was f...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.784782
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1197936
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we de...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1258411
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE). METHODS:Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant. RESULTS:The PE group had significantly lower apelin...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1777300
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:Growth differentiation factor-15 (GDF-15) is a stress-induced cytokine and related to the prognosis of cardiovascular diseases. Our purpose is to measure the maternal levels of GDF-15 in patients with early-onset preeclampsia (EOPE) and late-onset preeclampsia (LOPE). METHODS:This cross-sectional study was c...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2018.1524477
更新日期:2018-11-01 00:00:00
abstract::This study aimed to examine the incidence of hypertensive disorders of pregnancy (HDP) among Japanese women with oocyte donation pregnancy (ODP) aged 40 years or older and estimate whether the women with ODP were more likely to develop HDP than those with autologous oocyte pregnancy (AOP) and spontaneous pregnancy (SP...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1861461
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:We examined serum concentrations of basic fibroblast growth factor (bFGF) in women with hypertensive disorders in pregnancy and analyzed whether serum concentrations of bFGF can be used as a discriminator between mild and severe preeclampsia. METHODS:One hundred and twenty pregnant women were included in thi...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-120016790
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that the risk of preeclampsia in nulliparous women may be due to an anti-angiogenic state. METHODS:Maternal serum samples obtained in the third trimester from nulliparous (n = 86) and multiparous (n = 165) singleton uncomplicated pregnancies were analyzed for levels of angiogenic facto...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.858745
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701548240
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to reduce the rate of cesarean section (CS) in severe pregnancy-induced hypertension (PIH) by introducing a set of indicative criteria for CS. METHODS:Labor induction was attempted in Japanese patients (n = 41) with severe PIH after 34 weeks of gestation. Vital signs and symptoms th...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2015.1115061
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Pre-eclampsia is associated with significant maternal and neonatal complications, and delivery is often expedited to minimise complications. For randomised trials evaluating interventions in women with late-onset (>34 weeks) mild to moderate pre-eclampsia, no single outcome has been identified to be the most ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.837176
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Hypertension that develops after 20 gestational weeks and is defined as pregnancy-induced hypertension (PIH). The main cause of PIH is vasoconstriction and the thickening of vascular media, which decreases vascular capacity and increases peripheral resistance. One of the theories postulated to explain this p...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950600601835
更新日期:2006-01-01 00:00:00