Serum apelin and galectin-3 in preeclampsia in Iraq.

Abstract:

OBJECTIVE:This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE). METHODS:Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant. RESULTS:The PE group had significantly lower apelin and higher galectin-3 levels than the control group. PE group exhibited dyslipidemia and had higher β-cell functions than the controls. Galectin-3 level correlates with insulin, glucose, and IR. High galectin-3 also is correlated positively with dyslipidemia. CONCLUSION:In PE, there is a possible contribution of galectin-3 to the harmful effects of IR and dyslipidemia.

journal_name

Hypertens Pregnancy

authors

Sattar Taha A,Zahraei Z,Al-Hakeim HK

doi

10.1080/10641955.2020.1777300

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

379-386

issue

4

eissn

1064-1955

issn

1525-6065

journal_volume

39

pub_type

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