CA-125 and CRP are elevated in preeclampsia.

abstract：OBJECTIVE:To measure cytokine production in ex vivo stimulated leukocyte populations of women with normal pregnancy and those with preeclampsia. METHODS:Whole blood from preeclamptic and normal pregnant women was stimulated with LPS or PMA/Ca-ionophore. The percentages of IFN gamma and IL-2, 4, and 10 producing lympho...

journal_title：Hypertension in pregnancy

authors： van Nieuwenhoven AL,Moes H,Heineman MJ,Santema J,Faas MM

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE). METHODS:Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant. RESULTS:The PE group had significantly lower apelin...

journal_title：Hypertension in pregnancy

authors： Sattar Taha A,Zahraei Z,Al-Hakeim HK

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...

journal_title：Hypertension in pregnancy

authors： Gabbay A,Tzur T,Weintraub AY,Shoham-Vardi I,Sergienko R,Sheiner E

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. METHODS:Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every...

journal_title：Hypertension in pregnancy

authors： Samangaya RA,Mires G,Shennan A,Skillern L,Howe D,McLeod A,Baker PN

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...

journal_title：Hypertension in pregnancy

authors： Bryant AS,Seely EW,Cohen A,Lieberman E

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Preeclampsia and intrauterine growth retardation (IUGR) are associated with elevated concentrations of myeloperoxidase (MPO) and polymorphonuclear (PMN) elastase, which indicate maternal neutrophil activation. The aim of the study was to measure maternal MPO and PMN elastase plasma concentrations in second tr...

journal_title：Hypertension in pregnancy

authors： Stepan H,Heihoff-Klose A,Faber R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:PTX3, sFlt-1 and PlGF levels in maternal blood are altered in some obstetric diseases, such as preeclampsia (PE). Nonetheless, only few data on their expression in the fetal compartment have been reported so far. STUDY DESIGN:An observational study was performed by prospectively collecting maternal and fetal...

journal_title：Hypertension in pregnancy

authors： Algeri P,Ornaghi S,Bernasconi DP,Cappellini F,Signorini S,Brambilla P,Urban G,Vergani P

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...

journal_title：Hypertension in pregnancy

authors： Keshavarzi F,Mehdizadeh S,Khazaie H,Ghadami MR

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:DNA methylation is an important epigenetic regulator of gene transcription, and is involved in many diseases, which has been researched recently. In this study, we aimed to investigate DNA methylation and gene expression in preeclampsia placenta. Preeclampsia has been observed in patients with molar pregnancy...

journal_title：Hypertension in pregnancy

authors： Xuan J,Jing Z,Yuanfang Z,Xiaoju H,Pei L,Guiyin J,Yu Z

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To determine whether delivery mode influences placental chorionic plate arterial and venous vascular reactivity. METHODS:Normal term placentas were obtained after vaginal delivery or cesarean section. Chorionic plate arterial and venous function was assessed by wire myography. RESULTS:Sodium nitroprusside-i...

journal_title：Hypertension in pregnancy

authors： Mills TA,Baker PN,Wareing M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Women with a history of preeclampsia have an increased risk of cardiovascular disease. Gynaecologists have an important role in the counselling and management of cardiovascular risk factors after preeclampsia. We aimed to assess the role of gynaecologists in informing women on interventions and risk factor fo...

journal_title：Hypertension in pregnancy

authors： van Kesteren F,Visser S,Hermes W,Teunissen PW,Franx A,van Pampus MG,Mol BW,de Groot CJ

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Chymase, a chymotrypsin-like protease, is a non-ACE angiotensin II (Ang II) generating enzyme. We determined if maternal chymotrypsin-like protease/chymase activity was increased in women with preeclampsia (PE). METHODS:Maternal plasma was extracted from venous blood of healthy nonpregnant women, women with ...

journal_title：Hypertension in pregnancy

authors： Wang Y,Gu Y,Lewis DF,Alexander JS,Granger DN

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To characterize the maternal and fetal presentation of abruptio placentae and associated maternal and fetal morbidity and mortality by mode of delivery and fetal status on admission. STUDY DESIGN:Perinatal data (gestational age > 24 weeks) from women with abruptio placentae at a tertiary referral center were...

journal_title：Hypertension in pregnancy

authors： Witlin AG,Sibai BM

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Growth differentiation factor-15 (GDF-15) is a stress-induced cytokine and related to the prognosis of cardiovascular diseases. Our purpose is to measure the maternal levels of GDF-15 in patients with early-onset preeclampsia (EOPE) and late-onset preeclampsia (LOPE). METHODS:This cross-sectional study was c...

journal_title：Hypertension in pregnancy

authors： Temel Yuksel I,Mathyk BA,Aslan Cetin B,Turhan U,Okumus ZG,Yetkin Yildirim G,Acar DK

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:We compared second pregnancy outcomes among women with and without preeclampsia in their first pregnancies who all had second pregnancies without preeclampsia. METHODS:One hundred thirty women with and 6148 without preeclampsia in their first pregnancies, who all had nonpreeclamptic second pregnancies, were...

journal_title：Hypertension in pregnancy

authors： Lain KY,Krohn MA,Roberts JM

更新日期：2005-01-01 00:00:00

abstract：:Objectives: Establishment of association between: (a) Val158Met COMT (G1947A) polymorphism and preeclampsia; (b) cytokines gene expression and COMT genotypes. Methods: 50 preeclampsia and 50 healthy pregnant women were enrolled. COMT genotyping was done by PCR/RFLP. TNF-α, IL-1β, and IL-6 mRNA levels were determined b...

journal_title：Hypertension in pregnancy

authors： Sljivancanin Jakovljevic T,Kontic-Vucinic O,Nikolic N,Carkic J,Milasin J

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies. METHODS:We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnanc...

journal_title：Hypertension in pregnancy

authors： Suzuki S,Yoneyama Y,Sawa R,Shin S,Araki T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The diagnostic value of affinity-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis to distinguish preeclampsia (PE) from matched controls was tested in a multicenter setting. METHODS:Serum samples of preeclamptic (n = 60) and healthy pregnant women (n = 66) from four...

journal_title：Hypertension in pregnancy

authors： Pecks U,Schütt A,Röwer C,Reimer T,Schmidt M,Preschany S,Stepan H,Rath W,Glocker MO

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Assess the actual rate of eclampsia in Sweden, describe the clinical picture of the disease and the maternal and perinatal outcomes. METHODS:Analysis of data regarding incidence of eclampsia registered in the Swedish Medical Birth Register 1991-1992. The records of all the cases with the diagnosis of eclamps...

journal_title：Hypertension in pregnancy

authors： Kullberg G,Lindeberg S,Hanson U

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. METHODS:A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delive...

journal_title：Hypertension in pregnancy

authors： Tersigni C,Esposito G,Albanese A,D'Ippolito S,Sabatino G,Di Simone N,Caruso A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Trophoblast migration into the maternal circulation is increased in preeclampsia and can trigger the endothelial dysfunction that characterizes the clinical disease. We hypothesised that 'fetal trafficking' is increased in women with severe preeclampsia and that the quantity of trafficking is greater in women...

journal_title：Hypertension in pregnancy

authors： Byrne BM,Crowley A,Taulo F,Anthony J,O'Leary JJ,O'Herlihy C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and associated factors of superimposed preeclampsia among pregnant women with chronic hypertension. METHODS:A total of 300 pregnant women diagnosed with chronic hypertension were reviewed. Data were retrieved from medical records, including obstetric data, characteristics of hypert...

journal_title：Hypertension in pregnancy

authors： Boriboonhirunsarn D,Pradyachaipimol A,Viriyapak B

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To determine whether the incidence of hypotension or adverse fetal heart tracing (FHT) category change differed following antepartum administration of intravenous (IV) labetalol versus hydralazine. METHODS:Blood pressure and FHT categories were assessed one hour before and after medication administration. Hy...

journal_title：Hypertension in pregnancy

authors： Sharma KJ,Rodriguez M,Kilpatrick SJ,Greene N,Aghajanian P

更新日期：2016-01-01 00:00:00

abstract：:Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...

journal_title：Hypertension in pregnancy

authors： Wertaschnigg D,Wang R,Reddy M,Costa FDS,Mol BWJ,Rolnik DL

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...

journal_title：Hypertension in pregnancy

authors： Williams VK,Griffiths AB,Carbone S,Hague WM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:The aim was to identify differences in microRNA expression between patients with and without preeclampsia. METHODS:Microarray-based study was carried out with placental samples. RESULTS:Comparison of eight previous studies with the current study revealed a total of 138 microRNAs; only 20/138 (14%), however,...

journal_title：Hypertension in pregnancy

authors： Betoni JS,Derr K,Pahl MC,Rogers L,Muller CL,Packard RE,Carey DJ,Kuivaniemi H,Tromp G

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE). METHODS:A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and materna...

journal_title：Hypertension in pregnancy

authors： Christiansen M,Hedley PL,Placing S,Wøjdemann KR,Carlsen AL,Jørgensen JM,Gjerris AC,Shalmi AC,Rode L,Sundberg K,Tabor A

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To investigate the importance of prostacyclin and nitric oxide synthesis in endothelium-dependent relaxation in myometrial resistance vessels, and to test the hypothesis that a deficiency in nitric oxide synthesis contributes to the known alterations in endothelial function in preeclampsia. METHODS:Thirty-si...

journal_title：Hypertension in pregnancy

authors： Ashworth JR,Baker PN,Warren AY,Johnson IR

更新日期：1999-01-01 00:00:00

abstract：:The pathophysiology of preeclampsia (PET) implicates an inflammatory dysfunction. This study profiled this host response by challenging whole blood with lipopolysaccharide. Multiplex immunoassays determined interleukin (IL)-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12(p70), IL-13, IL-17, granulocyte/granulo...

journal_title：Hypertension in pregnancy

authors： Brewster JA,Orsi NM,Gopichandran N,Ekbote UV,Cadogan E,Walker JJ

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of ...

journal_title：Hypertension in pregnancy

authors： Shental O,Friger M,Sheiner E

更新日期：2010-01-01 00:00:00