Comprehensive analysis of DNA methylation and gene expression of placental tissue in preeclampsia patients.

abstract：OBJECTIVE:Women with a history of preeclampsia have an increased risk of cardiovascular disease. Gynaecologists have an important role in the counselling and management of cardiovascular risk factors after preeclampsia. We aimed to assess the role of gynaecologists in informing women on interventions and risk factor fo...

journal_title：Hypertension in pregnancy

authors： van Kesteren F,Visser S,Hermes W,Teunissen PW,Franx A,van Pampus MG,Mol BW,de Groot CJ

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:(i) To compare the levels of soluble Fas (sFas) in the sera of patients with variable degrees of preeclampsia and in healthy gravidas; and (ii) to correlate sFas with clinical, laboratory, and Doppler parameters in preeclampsia. METHODS:Fifty patients with mild preeclampsia, 50 patients with severe preeclam...

journal_title：Hypertension in pregnancy

authors： El-Sherbiny W,Soliman A,El-Mazny A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Case report of a 35-year-old gravida 3, para 2, at 40 + 6 weeks with massive respiratory dysfunction with need of oxygenation, requiring cesarean section. CASE REPORT:Postpartum investigations revealed pathological cardiomegaly with left ventricular failure (NYHAIV). Cardiac biopsy diagnosed postpartum dilat...

journal_title：Hypertension in pregnancy

authors： Freerksen N,Jaekel J,Menon AK,Maass N,Bauerschlag D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...

journal_title：Hypertension in pregnancy

authors： Gabbay A,Tzur T,Weintraub AY,Shoham-Vardi I,Sergienko R,Sheiner E

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. METHODS:Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every...

journal_title：Hypertension in pregnancy

authors： Samangaya RA,Mires G,Shennan A,Skillern L,Howe D,McLeod A,Baker PN

更新日期：2009-08-01 00:00:00

abstract：:Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...

journal_title：Hypertension in pregnancy

authors： Wertaschnigg D,Wang R,Reddy M,Costa FDS,Mol BWJ,Rolnik DL

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between the cancer antigen-125 (CA-125) and C-reactive protein (CRP) with preeclampsia and eclampsia. METHODS:The study group included 54 preeclamptic/eclamptic women, and 56 healthy pregnant women served as the control group. Mean arterial pressure (MAP) and albumin levels were...

journal_title：Hypertension in pregnancy

authors： Cebesoy FB,Balat O,Dikensoy E,Kalayci H,Ibar Y

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and associated factors of superimposed preeclampsia among pregnant women with chronic hypertension. METHODS:A total of 300 pregnant women diagnosed with chronic hypertension were reviewed. Data were retrieved from medical records, including obstetric data, characteristics of hypert...

journal_title：Hypertension in pregnancy

authors： Boriboonhirunsarn D,Pradyachaipimol A,Viriyapak B

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we de...

journal_title：Hypertension in pregnancy

authors： Lin LT,Hu LY,Tang PL,Tsui KH,Cheng JT,Huang WC,Chang HT

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To report a case of cardiac arrhythmia related to a low dose of endovenous lanatoside C. CASE REPORT:A 23-year-old pregnant woman with mitral regurgitation complicated with preeclampsia and pulmonary edema presented 2 episodes of atrial tachycardia induced by a intravenous digitalis (2 mg, IV and 1 mg, IV, r...

journal_title：Hypertension in pregnancy

authors： Roscani MG,Zanati SG,Magalhães CG,Borges VT,Matsubara BB

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...

journal_title：Hypertension in pregnancy

authors： Karinen L,Leinonen M,Bloigu A,Paldanius M,Koskela P,Saikku P,Hartikainen AL,Jarvelin MR,Pouta A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Escherichia coli O157:H7 is a common cause of bacterial gastroenteritis and may increase the risk of hypertension. We studied the risk of hypertension in pregnancy following a large E. coli O157:H7 outbreak that occurred in Walkerton, Canada, in the year 2000. METHODS:We linked data collected from Walkerton...

journal_title：Hypertension in pregnancy

authors： Nevis IF,Sontrop JM,Clark WF,Huang A,McDonald S,Thabane L,Moist L,Macnab JJ,Suri R,Garg AX

更新日期：2013-11-01 00:00:00

abstract：:Objectives: Establishment of association between: (a) Val158Met COMT (G1947A) polymorphism and preeclampsia; (b) cytokines gene expression and COMT genotypes. Methods: 50 preeclampsia and 50 healthy pregnant women were enrolled. COMT genotyping was done by PCR/RFLP. TNF-α, IL-1β, and IL-6 mRNA levels were determined b...

journal_title：Hypertension in pregnancy

authors： Sljivancanin Jakovljevic T,Kontic-Vucinic O,Nikolic N,Carkic J,Milasin J

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Trophoblast migration into the maternal circulation is increased in preeclampsia and can trigger the endothelial dysfunction that characterizes the clinical disease. We hypothesised that 'fetal trafficking' is increased in women with severe preeclampsia and that the quantity of trafficking is greater in women...

journal_title：Hypertension in pregnancy

authors： Byrne BM,Crowley A,Taulo F,Anthony J,O'Leary JJ,O'Herlihy C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The angiogenic-antiangiogenic imbalance evident in preeclampsia (PE) may be used as a predictive tool to identify women likely to develop the clinical features in early pregnancy. METHOD:This retrospective study examined normotensive pregnant (n = 38) and preeclamptic (n = 38) HIV-infected and uninfected wom...

journal_title：Hypertension in pregnancy

authors： Thakoordeen S,Moodley J,Naicker T

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The aim was to identify differences in microRNA expression between patients with and without preeclampsia. METHODS:Microarray-based study was carried out with placental samples. RESULTS:Comparison of eight previous studies with the current study revealed a total of 138 microRNAs; only 20/138 (14%), however,...

journal_title：Hypertension in pregnancy

authors： Betoni JS,Derr K,Pahl MC,Rogers L,Muller CL,Packard RE,Carey DJ,Kuivaniemi H,Tromp G

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. METHODS:A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delive...

journal_title：Hypertension in pregnancy

authors： Tersigni C,Esposito G,Albanese A,D'Ippolito S,Sabatino G,Di Simone N,Caruso A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Some evidence indicated the role of nutrition in the development of hypertensive disorders of pregnancy. METHODS:This case-control study was conducted on 113 women with gestational hypertension and 150 healthy pregnant women referred to Shahid Akbarabadi Hospital in Tehran. A demographic questionnaire was f...

journal_title：Hypertension in pregnancy

authors： Kazemian E,Dorosty-Motlagh AR,Sotoudeh G,Eshraghian MR,Ansary S,Omidian M

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to investigate the value of placental growth factor (PLGF), soluble fms-like tyrosine kinase-1 (sFlt-1) and sFlt-1/PLGF ratio, in predicting symptomatic preeclampsia (PE). METHODS:A prospective longitudinal study was carried out on 71 high risk preeclamptic women cohort. All of t...

journal_title：Hypertension in pregnancy

authors： Teixeira PG,Reis ZS,Andrade SP,Rezende CA,Lage EM,Velloso EP,Santana CA,Cabral AC

更新日期：2013-08-01 00:00:00

abstract：:Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female...

journal_title：Hypertension in pregnancy

authors： Igonina TN,Ragaeva DS,Petrova OM,Rozkova IN,Brusentsev EY,Amstislavsky SY

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...

journal_title：Hypertension in pregnancy

authors： Keshavarzi F,Mehdizadeh S,Khazaie H,Ghadami MR

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Construct a new preeclampsia predicting algorithm in twins. METHODS:Twins sampled at 10-13 and 16-20 gestational weeks and their marker values were log transformed into multiples of the gestation-specific medians (MoMs) for singletons and entered into a new logistic regression model with/without prior risk ...

journal_title：Hypertension in pregnancy

authors： Maymon R,Trahtenherts A,Svirsky R,Melcer Y,Madar-Shapiro L,Klog E,Meiri H,Cuckle H

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...

journal_title：Hypertension in pregnancy

authors： Williams VK,Griffiths AB,Carbone S,Hague WM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies. METHODS:We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnanc...

journal_title：Hypertension in pregnancy

authors： Suzuki S,Yoneyama Y,Sawa R,Shin S,Araki T

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To assess hemodynamic and NT-proANP changes in women with chronic hypertension during pregnancy. METHODS:Stroke volume index (SI), heart rate (HR), cardiac output index (CI), systemic vascular resistance index (SVRI), pulse wave velocity (PWV), and left cardiac work index (LCWI) were measured using whole-bod...

journal_title：Hypertension in pregnancy

authors： Tihtonen K,Kööbi T,Huhtala H,Uotila J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To compare maturity of placentas from women with hypertensive disorders with those from normotensive pregnancies and to determine the relationship between placental maturity (PM) and the diagnosis of small-for-gestational-age (SGA) in the newborns. MATERIALS AND METHODS:We examined placental stained specime...

journal_title：Hypertension in pregnancy

authors： Ruiz-Quiñonez G,Reza-López SA,Chávez-Corral DV,Sánchez-Ramírez B,Leal-Berumen I,Levario-Carrillo M

更新日期：2014-05-01 00:00:00

abstract：:The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of pregnancy were compared with naturally conceived controls. Surgery dur...

journal_title：Hypertension in pregnancy

authors： Rozkova I,Brusentsev E,Igonina T,Ragaeva D,Petrova O,Tikhonova MA,Akopyan AA,Amstislavskaya TG,Antonov YV,Amstislavsky S

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:We examined serum concentrations of basic fibroblast growth factor (bFGF) in women with hypertensive disorders in pregnancy and analyzed whether serum concentrations of bFGF can be used as a discriminator between mild and severe preeclampsia. METHODS:One hundred and twenty pregnant women were included in thi...

journal_title：Hypertension in pregnancy

authors： Hohlagschwandtner M,Knöfler M,Ploner M,Zeisler H,Joura EA,Husslein P

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the risk of preeclampsia in nulliparous women may be due to an anti-angiogenic state. METHODS:Maternal serum samples obtained in the third trimester from nulliparous (n = 86) and multiparous (n = 165) singleton uncomplicated pregnancies were analyzed for levels of angiogenic facto...

journal_title：Hypertension in pregnancy

authors： Bdolah Y,Elchalal U,Natanson-Yaron S,Yechiam H,Bdolah-Abram T,Greenfield C,Goldman-Wohl D,Milwidsky A,Rana S,Karumanchi SA,Yagel S,Hochner-Celnikier D

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To assess seasonal patterns and monthly variations in the incidence of preeclampsia in the Jewish and Bedouin population in Israel, assuming that ethnicity and environmental factors may have a role in the causal mechanism. METHODS:A retrospective population-based study comparing all singleton pregnancies of ...

journal_title：Hypertension in pregnancy

authors： Shental O,Friger M,Sheiner E

更新日期：2010-01-01 00:00:00