Abstract:
OBJECTIVE:Assess the actual rate of eclampsia in Sweden, describe the clinical picture of the disease and the maternal and perinatal outcomes. METHODS:Analysis of data regarding incidence of eclampsia registered in the Swedish Medical Birth Register 1991-1992. The records of all the cases with the diagnosis of eclampsia in Sweden during 1991-1992 were retrospectively evaluated regarding maternal and fetal outcomes. RESULTS:The incidence of eclampsia after case review was 3.3/10,000 births. There was no maternal mortality. Severe maternal complications occurred in 30%. Recurrent fits were reported in 41%. Antenatal eclampsia was usually either not preceded by symptoms or signs of preeclampsia or by just a very short period of prodromal symptoms. Among intrapartum and postnatal cases of eclampsia, preeclampsia or high blood pressure was more frequently noted when convulsions occurred. Perinatal mortality rate was 4/80 (4.7%). Of the infants, 13% were small for gestational age. CONCLUSION:Compared with earlier studies, the incidence of eclampsia has increased significantly. It is questionable whether the incidence of eclampsia could be reduced by earlier diagnosis and treatment of preeclampsia. The risk of severe complications and recurrent fits was substantial, which underlines the importance of adequate treatment of eclampsia.
journal_name
Hypertens Pregnancyjournal_title
Hypertension in pregnancyauthors
Kullberg G,Lindeberg S,Hanson Udoi
10.1081/PRG-120002906keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
13-21issue
1eissn
1064-1955issn
1525-6065pii
120002906journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:Oxidative stress and a generalized inflammatory state are features of preeclampsia (PE). The objective of this study was to compare the levels of products of inflammatory reaction and oxidative stress markers in patients with PE, and to determine the relationship between oxidative stress and inflammation in P...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950802233064
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we de...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1258411
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:We examined serum concentrations of basic fibroblast growth factor (bFGF) in women with hypertensive disorders in pregnancy and analyzed whether serum concentrations of bFGF can be used as a discriminator between mild and severe preeclampsia. METHODS:One hundred and twenty pregnant women were included in thi...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-120016790
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to reduce the rate of cesarean section (CS) in severe pregnancy-induced hypertension (PIH) by introducing a set of indicative criteria for CS. METHODS:Labor induction was attempted in Japanese patients (n = 41) with severe PIH after 34 weeks of gestation. Vital signs and symptoms th...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2015.1115061
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Chymase, a chymotrypsin-like protease, is a non-ACE angiotensin II (Ang II) generating enzyme. We determined if maternal chymotrypsin-like protease/chymase activity was increased in women with preeclampsia (PE). METHODS:Maternal plasma was extracted from venous blood of healthy nonpregnant women, women with ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641950802001842
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE(S):We tested the hypothesis that twin pregnancies would lead to increased maternal plasma homocysteine. We further hypothesized that twin pregnancies complicated by preeclampsia would have increased plasma homocysteine compared to twin pregnancies without preeclampsia and normal singleton pregnancies. METHOD...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-45774
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To investigate sestrin 2 (SESN2) levels in preeclampsia (PE) cases and uncomplicated pregnancies. METHODS:Cross-sectional study including 26 pregnant women with PE, 24 with severe-PE, and 30 randomly selected healthy pregnant women. RESULTS:The mean arterial pressure, severe proteinuria, number of HELLP syn...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2018.1540702
更新日期:2019-02-01 00:00:00
abstract::The study investigates how surgery during pregnancy, i.e., sham operation associated with embryo transfer, affects hypertensive phenotype in ISIAH rats genetically predisposed to hypertension. ISIAH rats born after maternal surgery at fourth day of pregnancy were compared with naturally conceived controls. Surgery dur...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2020.1762894
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:PTX3, sFlt-1 and PlGF levels in maternal blood are altered in some obstetric diseases, such as preeclampsia (PE). Nonetheless, only few data on their expression in the fetal compartment have been reported so far. STUDY DESIGN:An observational study was performed by prospectively collecting maternal and fetal...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2014.903962
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To identify parameters that may assist clinicians in predicting which women will develop preeclampsia (PE) after initially presenting with gestational hypertension (GH). METHODS:118 women were recruited to the study with GH or PE. They were divided into three groups based on their diagnosis at delivery- (1) ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950601147952
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Case report of a 35-year-old gravida 3, para 2, at 40 + 6 weeks with massive respiratory dysfunction with need of oxygenation, requiring cesarean section. CASE REPORT:Postpartum investigations revealed pathological cardiomegaly with left ventricular failure (NYHAIV). Cardiac biopsy diagnosed postpartum dilat...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2012.679014
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Leukocytes are activated in women with preeclampsia, but the class of leukocytes that infiltrates the maternal vasculature and, therefore, is most likely to cause vascular dysfunction is not known. METHODS:Subcutaneous fat biopsies were obtained at Cesarean section or abdominal surgery from 7 normal non-preg...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950801958067
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2018.1498879
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1197936
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Pre-eclampsia is associated with significant maternal and neonatal complications, and delivery is often expedited to minimise complications. For randomised trials evaluating interventions in women with late-onset (>34 weeks) mild to moderate pre-eclampsia, no single outcome has been identified to be the most ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.837176
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate maternal and fetal outcome of the subsequent pregnancy of primiparous women with a history of early-onset intrauterine growth restriction (IUGR), prompting delivery before 34 weeks of gestation, without concomitant maternal hypertensive disease. DESIGN:Retrospective coho...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2010.484080
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine whether Chlamydia pneumoniae antibodies and highly sensitive C-reactive protein (hsCRP) levels in maternal sera are associated with preeclampsia or gestational hypertension. METHODS:C. pneumoniae antibodies and hsCRP levels were measured in maternal serum during first trimester (mean, 10.4 weeks...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701885188
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The aim was to identify differences in microRNA expression between patients with and without preeclampsia. METHODS:Microarray-based study was carried out with placental samples. RESULTS:Comparison of eight previous studies with the current study revealed a total of 138 microRNAs; only 20/138 (14%), however,...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,评审
doi:10.3109/10641955.2013.807819
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS:In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase ch...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2016.1250904
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:DNA methylation is an important epigenetic regulator of gene transcription, and is involved in many diseases, which has been researched recently. In this study, we aimed to investigate DNA methylation and gene expression in preeclampsia placenta. Preeclampsia has been observed in patients with molar pregnancy...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2015.1117099
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Women with a history of preeclampsia have an increased risk of cardiovascular disease. Gynaecologists have an important role in the counselling and management of cardiovascular risk factors after preeclampsia. We aimed to assess the role of gynaecologists in informing women on interventions and risk factor fo...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2015.1100311
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To determine whether delivery mode influences placental chorionic plate arterial and venous vascular reactivity. METHODS:Normal term placentas were obtained after vaginal delivery or cesarean section. Chorionic plate arterial and venous function was assessed by wire myography. RESULTS:Sodium nitroprusside-i...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10601330701274824
更新日期:2007-01-01 00:00:00
abstract::Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,评审
doi:10.1080/10641955.2019.1708383
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:The angiogenic-antiangiogenic imbalance evident in preeclampsia (PE) may be used as a predictive tool to identify women likely to develop the clinical features in early pregnancy. METHOD:This retrospective study examined normotensive pregnant (n = 38) and preeclamptic (n = 38) HIV-infected and uninfected wom...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641955.2017.1280049
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies. METHODS:We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnanc...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/prg-100101988
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.877925
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to investigate the value of placental growth factor (PLGF), soluble fms-like tyrosine kinase-1 (sFlt-1) and sFlt-1/PLGF ratio, in predicting symptomatic preeclampsia (PE). METHODS:A prospective longitudinal study was carried out on 71 high risk preeclamptic women cohort. All of t...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.3109/10641955.2013.807818
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To provide long-term follow-up data on women with a history of hemolysis, elevated liver enzymes, and low platelets [(H)ELLP] syndrome regarding the risk of recurrence in subsequent pregnancies and disease in later life. METHODS:All women admitted to the Academic Medical Centre between January 1984 and Janua...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1081/PRG-100104168
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章,meta分析,评审
doi:10.1080/10641955.2016.1178772
更新日期:2016-08-01 00:00:00
abstract::The pathophysiology of preeclampsia (PET) implicates an inflammatory dysfunction. This study profiled this host response by challenging whole blood with lipopolysaccharide. Multiplex immunoassays determined interleukin (IL)-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12(p70), IL-13, IL-17, granulocyte/granulo...
journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950701826067
更新日期:2008-01-01 00:00:00