Interactions between inflammatory and oxidative stress in preeclampsia.

abstract：OBJECTIVE:To examine the management of early-onset preeclampsia and its maternal and fetal morbidity and mortality. DESIGN:Retrospective cohort study of 49,812 births at a university teaching hospital between June 1986 and March 1997. Seventy-one women were identified with a diagnosis of preeclampsia with an onset at ...

journal_title：Hypertension in pregnancy

authors： Murphy DJ,Stirrat GM

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE). METHODS:A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and materna...

journal_title：Hypertension in pregnancy

authors： Christiansen M,Hedley PL,Placing S,Wøjdemann KR,Carlsen AL,Jørgensen JM,Gjerris AC,Shalmi AC,Rode L,Sundberg K,Tabor A

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Case report of a 35-year-old gravida 3, para 2, at 40 + 6 weeks with massive respiratory dysfunction with need of oxygenation, requiring cesarean section. CASE REPORT:Postpartum investigations revealed pathological cardiomegaly with left ventricular failure (NYHAIV). Cardiac biopsy diagnosed postpartum dilat...

journal_title：Hypertension in pregnancy

authors： Freerksen N,Jaekel J,Menon AK,Maass N,Bauerschlag D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The aim was to identify differences in microRNA expression between patients with and without preeclampsia. METHODS:Microarray-based study was carried out with placental samples. RESULTS:Comparison of eight previous studies with the current study revealed a total of 138 microRNAs; only 20/138 (14%), however,...

journal_title：Hypertension in pregnancy

authors： Betoni JS,Derr K,Pahl MC,Rogers L,Muller CL,Packard RE,Carey DJ,Kuivaniemi H,Tromp G

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Caesarean section (CS) is one of the most frequently performed surgical procedures worldwide. Surgical variants include closure and non-closure of the peritoneum: in case of non-suturing the visceral peritoneum (VP), abnormal fluid collections such as blood clots may lead to formation of a hematoperitoneum...

journal_title：Hypertension in pregnancy

authors： Malvasi A,Tinelli A,Hudelist G,Vergara D,Martignago R,Tinelli R

更新日期：2009-01-01 00:00:00

abstract：:Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unc...

journal_title：Hypertension in pregnancy

authors： Wertaschnigg D,Wang R,Reddy M,Costa FDS,Mol BWJ,Rolnik DL

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Although preeclampsia remains a major cause of maternal and fetal morbidity and mortality, its pathogenesis is not fully understood. Coagulation and fibrinolysis changes were suggested to have a role in the pathogenesis of preeclampsia. OBJECTIVES:A case-control study was conducted in Medani Hospital, Sudan...

journal_title：Hypertension in pregnancy

authors： Elzein HO,Muddathir AR,Rida M,Rayis DA,Elhassan EM,Adam I

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To compare fibrinogen concentration and factor VIII activity obtained from pregnant women with preeclampsia with those obtained from women with either normal pregnancies or with complications unrelated to preeclampsia. MATERIALS AND METHODS:Fibrinogen concentration and factor VIII activity were measured in t...

journal_title：Hypertension in pregnancy

authors： Williams VK,Griffiths AB,Carbone S,Hague WM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Women with a history of preeclampsia have an increased risk of cardiovascular disease. Gynaecologists have an important role in the counselling and management of cardiovascular risk factors after preeclampsia. We aimed to assess the role of gynaecologists in informing women on interventions and risk factor fo...

journal_title：Hypertension in pregnancy

authors： van Kesteren F,Visser S,Hermes W,Teunissen PW,Franx A,van Pampus MG,Mol BW,de Groot CJ

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to investigate the value of placental growth factor (PLGF), soluble fms-like tyrosine kinase-1 (sFlt-1) and sFlt-1/PLGF ratio, in predicting symptomatic preeclampsia (PE). METHODS:A prospective longitudinal study was carried out on 71 high risk preeclamptic women cohort. All of t...

journal_title：Hypertension in pregnancy

authors： Teixeira PG,Reis ZS,Andrade SP,Rezende CA,Lage EM,Velloso EP,Santana CA,Cabral AC

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To determine if the phosphodiesterase type 5 inhibitor sildenafil prolongs pregnancy in women with preeclampsia. METHODS:Women with preeclampsia at gestational ages 24-34 weeks were recruited from nine hospitals in the UK, and randomly assigned to sildenafil citrate or placebo. Medication was increased every...

journal_title：Hypertension in pregnancy

authors： Samangaya RA,Mires G,Shennan A,Skillern L,Howe D,McLeod A,Baker PN

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To report about a case of complicated late postpartum eclampsia where neonatal low birth weight could be considered a predictive factor of placental sufferance. METHODS:A 25-year-old woman, without medical or familiar history for hypertension or cerebrovascular diseases, underwent a normal spontaneous delive...

journal_title：Hypertension in pregnancy

authors： Tersigni C,Esposito G,Albanese A,D'Ippolito S,Sabatino G,Di Simone N,Caruso A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Chymase, a chymotrypsin-like protease, is a non-ACE angiotensin II (Ang II) generating enzyme. We determined if maternal chymotrypsin-like protease/chymase activity was increased in women with preeclampsia (PE). METHODS:Maternal plasma was extracted from venous blood of healthy nonpregnant women, women with ...

journal_title：Hypertension in pregnancy

authors： Wang Y,Gu Y,Lewis DF,Alexander JS,Granger DN

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Low-dose aspirin can reduce the incidence of preeclampsia and intrauterine growth restriction (IUGR). However, the effects of ethnicity upon low-dose aspirin's efficacy has not been analyzed. Here, we comparatively evaluated the efficacy of low-dose aspirin in preventing preeclampsia and related fetal compli...

journal_title：Hypertension in pregnancy

authors： Gan J,He H,Qi H

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3'A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE). METHODS:In total, 89 women with PE and 89 control women were included in the study. Genotyping was done by polymerase ch...

journal_title：Hypertension in pregnancy

authors： Karakus S,Bagci B,Bagci G,Sancakdar E,Yildiz C,Akkar O,Cetin A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to determine if heat shock protein 70 (Hsp 70), a marker of cellular stress, is elevated in pregnancies complicated by severe preeclampsia. METHODS:Maternal blood was collected from women with severe preeclampsia (n=47) matched for delivery gestational age to normotensive pregnan...

journal_title：Hypertension in pregnancy

authors： Livingston JC,Ahokas R,Haddad B,Sibai BM,Awaads R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To compare connexin expression in omental resistance arteries from preeclamptic women and normal gravidas. METHODS:Small arteries (approximately 200-400 microm i.d.) were dissected from omental fat biopsies, taken at cesarean delivery from normotensive and preeclamptic women. Vessels were frozen and homogeni...

journal_title：Hypertension in pregnancy

authors： Umans JG,Lindheimer MD,Hack B,Davidson-Garcia CA

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to reduce the rate of cesarean section (CS) in severe pregnancy-induced hypertension (PIH) by introducing a set of indicative criteria for CS. METHODS:Labor induction was attempted in Japanese patients (n = 41) with severe PIH after 34 weeks of gestation. Vital signs and symptoms th...

journal_title：Hypertension in pregnancy

authors： Shibata T,Nakago S,Kato H,Tokuda H,Matsuki R,Kotsuji F

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Obstructive sleep apnea (OSA) is a risk factor for adverse pregnancy outcomes. The aim of this study was to evaluate the association between OSA and preeclampsia. METHODS:Between 30 and 39 weeks gestation, objective sleep apnea were evaluated in 38 normal pregnant and 40 preeclamptic women. Preeclampsia was ...

journal_title：Hypertension in pregnancy

authors： Keshavarzi F,Mehdizadeh S,Khazaie H,Ghadami MR

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To examine the association between calcium levels during the first trimester of pregnancy and preeclampsia. METHODS:The study population included registered births (n = 5233) in a tertiary medical center between 2001 and 2011. A comparison was performed between women with and without hypocalcemia during the ...

journal_title：Hypertension in pregnancy

authors： Gabbay A,Tzur T,Weintraub AY,Shoham-Vardi I,Sergienko R,Sheiner E

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and associated factors of superimposed preeclampsia among pregnant women with chronic hypertension. METHODS:A total of 300 pregnant women diagnosed with chronic hypertension were reviewed. Data were retrieved from medical records, including obstetric data, characteristics of hypert...

journal_title：Hypertension in pregnancy

authors： Boriboonhirunsarn D,Pradyachaipimol A,Viriyapak B

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:DNA methylation is an important epigenetic regulator of gene transcription, and is involved in many diseases, which has been researched recently. In this study, we aimed to investigate DNA methylation and gene expression in preeclampsia placenta. Preeclampsia has been observed in patients with molar pregnancy...

journal_title：Hypertension in pregnancy

authors： Xuan J,Jing Z,Yuanfang Z,Xiaoju H,Pei L,Guiyin J,Yu Z

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the risk of preeclampsia in nulliparous women may be due to an anti-angiogenic state. METHODS:Maternal serum samples obtained in the third trimester from nulliparous (n = 86) and multiparous (n = 165) singleton uncomplicated pregnancies were analyzed for levels of angiogenic facto...

journal_title：Hypertension in pregnancy

authors： Bdolah Y,Elchalal U,Natanson-Yaron S,Yechiam H,Bdolah-Abram T,Greenfield C,Goldman-Wohl D,Milwidsky A,Rana S,Karumanchi SA,Yagel S,Hochner-Celnikier D

更新日期：2014-05-01 00:00:00

abstract：:The aim of this study is to compare ADAMTS (A Disintegrin and Metalloprotease Domains with Thrombospondins motifs) 1, 4, 12, and 13 levels in maternal and cord blood and placental tissue between preeclampsia and uncomplicated pregnancies. The enzyme-linked immunosorbent assay (ELISA) results showed that ADAMTS 1, 4, 1...

journal_title：Hypertension in pregnancy

authors： Namlı Kalem M,Kalem Z,Yüce T,Soylemez F

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To determine whether the higher rate of preeclampsia previously reported in Black women is attributable to a higher rate of chronic hypertension in that group. METHODS:Rates and severity of pregnancy-related hypertensive disease in Black and White women with and without chronic hypertension were reviewed fro...

journal_title：Hypertension in pregnancy

authors： Bryant AS,Seely EW,Cohen A,Lieberman E

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the incidence of hypertensive disorders is different in monozygotic compared to dizygotic twin pregnancies. METHODS:A registry-based survey of twin pregnancies delivered during 2003 to 2012. We used the best clinical estimate of zygosity based on the concept that all monochorionic twins ...

journal_title：Hypertension in pregnancy

authors： Lučovnik M,Blickstein I,Lasič M,Fabjan-Vodušek V,Bržan-Simenc G,Verdenik I,Tul N

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:This study investigated endothelin-1 (ET-1) production induced by vascular endothelial growth factor (VEGF) in two different vascular wall cell types. METHODS:We analyzed the effect of endothelin-converting enzyme-1 (ECE-1) inhibitor and tissue inhibitors of matrix metalloproteinase-2 (TIMP-2) on VEGF-induce...

journal_title：Hypertension in pregnancy

authors： Seol HJ,Oh MJ,Kim HJ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine the differences in histopathological features of basal decidua and placenta in cases of preeclampsia with or without fetal intrauterine growth restriction (IUGR). METHODS:A prospective case-control study included a study group consisting of 30 pregnant women with p...

journal_title：Hypertension in pregnancy

authors： Milosevic-Stevanovic J,Krstic M,Radovic-Janosevic D,Stefanovic M,Antic V,Djordjevic I

更新日期：2016-11-01 00:00:00

abstract：:We examined neurological and intellectual outcome of growth-restricted newborns of pregnancies complicated with preeclampsia and without preeclampsia. Seventy-five consecutive growth restricted newborns (<5th percentile) were prospectively followed up at 6 months' intervals. Newborns with major congenital malformation...

journal_title：Hypertension in pregnancy

authors： Many A,Fattal A,Leitner Y,Kupferminc MJ,Harel S,Jaffa A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:We examined serum concentrations of basic fibroblast growth factor (bFGF) in women with hypertensive disorders in pregnancy and analyzed whether serum concentrations of bFGF can be used as a discriminator between mild and severe preeclampsia. METHODS:One hundred and twenty pregnant women were included in thi...

journal_title：Hypertension in pregnancy

authors： Hohlagschwandtner M,Knöfler M,Ploner M,Zeisler H,Joura EA,Husslein P

更新日期：2002-01-01 00:00:00