Abstract:
:Osteoporosis is one of the most common diseases that leads to bone fractures. Dual-energy X-ray absorptiometry is currently employed to measure the bone mineral density and to diagnose osteoporosis. Alternatively, the dielectric properties of bones are found to be influenced by bone mineral density; hence, dielectric properties of bones may potentially be used to diagnose osteoporosis. Microwave tomographic imaging is currently in development to potentially measure in vivo dielectric properties of bone. Therefore, the foci of this work are to summarize all available dielectric data of bone in the microwave frequency range and to analyze the confounders that may have resulted in variations in reported data. This study also compares the relationship between the dielectric properties and bone quality reported across different studies. The review suggests that variations exist in the dielectric properties of bone and the relationship between bone volume fraction and dielectric properties is in agreement across all studies. Conversely, the evidence of a relationship between bone mineral density and dielectric properties is inconsistent across the studies. This summary of dielectric data of bone along with a comparison of the relationship between the dielectric properties and bone quality will accelerate the development of microwave tomographic imaging devices for the monitoring of osteoporosis. Graphical abstract ᅟ.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Amin B,Elahi MA,Shahzad A,Porter E,McDermott B,O'Halloran Mdoi
10.1007/s11517-018-1887-zsubject
Has Abstractpub_date
2019-01-01 00:00:00pages
1-13issue
1eissn
0140-0118issn
1741-0444pii
10.1007/s11517-018-1887-zjournal_volume
57pub_type
杂志文章,评审abstract::High-frequency nanosecond-pulsed electric fields were recently introduced for tumor or abnormal tissue ablation to solve some problems of conventional electroporation. However, it is necessary to study the thermal effects of high-field-intensity nanosecond pulses inside tissues. The multi-parametric analysis performed...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1589-3
更新日期:2017-07-01 00:00:00
abstract::Marfan syndrome (MFS) is a genetic disorder that affects connective tissue, impairing cardiovascular structures and function, such as heart valves and aorta. Thus, patients with Marfan disease have a higher risk of developing circulatory problems associated with mitral and aortic valves prolapse, manifested as dilated...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1524-7
更新日期:2017-03-01 00:00:00
abstract::Tissue hardness is related to tissue composition, and this is often changed by disease. It is therefore of interest to measure the hardness in an objective and non-invasive way. A tactile sensor based on a vibrating piezoelectric ceramic element in a feedback loop is described. When the sensor touches an object it pro...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513357
更新日期:1999-09-01 00:00:00
abstract::In the field of sports biomechanics and rehabilitation engineering, the possibility of computing, in real time, the angular displacements and derivatives of human joints, from a video of motion sequences, represents an appealing goal. In particular, applications of biofeedback protocols in rehabilitation can benefit f...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344878
更新日期:2003-03-01 00:00:00
abstract::The passive and active properties of the cochlear outer hair cell are studied. The outer hair cell is currently considered the major candidate for the active component of mammalian hearing. Understanding of its properties may explain the amplification and sharp frequency selectivity of the ear. To analyse the cell beh...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513294
更新日期:1999-03-01 00:00:00
abstract::Automatic identification of landmarks in cephalometry is very important and useful for orthognathic surgery. A computerised automatic cephalometric analysis system (CACAS), based on image processing, is presented. For an original X-ray image, median filtering and histogram equalisation are used to improve image qualit...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345280
更新日期:2001-05-01 00:00:00
abstract::Four ventricular fibrillation (VF) detection techniques were assessed using recordings of VF to evaluate sensitivity and VF-like recordings to evaluate specificity. The recordings were obtained from Coronary Care Unit patients. The techniques were: threshold crossing intervals (TCI); peaks in the autocorrelation funct...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446668
更新日期:1993-03-01 00:00:00
abstract::The management of postprandial glucose excursions in type 1 diabetes has a major impact on overall glycaemic control. In this work, we propose and evaluate various mechanistic models to characterize the disposal of meal-attributable glucose. Sixteen young volunteers with type 1 diabetes were subject to a variable-targ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1509-6
更新日期:2017-02-01 00:00:00
abstract::The problem of excess cerebrospinal fluid in the brain (hydrocephalus) is generally managed using a passive pressure or flow regulated mechanical shunt. Despite the success of such devices, they have been plagued with a number of problems. It is desirable to have a shunt valve that responds dynamically to the changing...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0716-9
更新日期:2011-01-01 00:00:00
abstract::Classification of cancerous genes from microarray data is an important research area in bioinformatics. Large amount of microarray data are available, but it is very costly to label them. This paper proposes an active learning model, a semi-supervised classification approach, to label the microarray data using which p...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02238-1
更新日期:2020-10-01 00:00:00
abstract::Long periods of bed rest negatively affect the human body organs, notably the cardiovascular system. To avert these negative effects and promote functional recovery in patients dealing with prolonged bed rest, the goal is to mobilize them as early as possible while controlling and stabilizing their cardiovascular syst...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-017-1628-8
更新日期:2017-09-01 00:00:00
abstract::Performance evaluations of ion-selective field-effect transistors (ISFETs) have been carried out using both quality-control materials and whole arterial blood samples. Comparison of the results from these evaluations suggests that the whole blood evaluation may be more useful when assessing the value of particular sen...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02442678
更新日期:1990-05-01 00:00:00
abstract::Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1499-4
更新日期:2017-02-01 00:00:00
abstract::Left ventricular assist devices (LVAD) emerges as an effective clinical device providing life-saving support to heart patients. The design of blood pump of an LVAD involves incredible accuracy and thorough understanding of hemodynamics to mimic the functionality of a healthy ventricle. This work studies hemodynamics a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02097-5
更新日期:2020-02-01 00:00:00
abstract::Taking advantage of motion sensing technology, a quantitative assessment method for lower limbs motor function of cerebral palsy (CP) based on the gross motor function measurement (GMFM)-24 scale was explored in this study. According to the motion analysis on GMFM-24 scale, we translated the assessment problem of GMFM...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02076-w
更新日期:2020-01-01 00:00:00
abstract::To study the effects of the geometrical characteristics of a framing coil on aneurysm thromboembolization efficacy, the hemodynamics in lateral aneurysms filled with coils having a different shape, orientation, and thickness were analyzed using computational fluid dynamics. The aneurysms packed with vortex and cage-sh...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1073-2
更新日期:2013-09-01 00:00:00
abstract::The vagus nerves convey both afferent and efferent information about autonomic activity related to cardiovascular functions. Those functions have been shown to change due to epileptic seizures, which suggests that ictal events might be detected via the vagus electroneurogram (VENG). In this study, we characterize the ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-011-0782-7
更新日期:2011-09-01 00:00:00
abstract::The effect of flow direction on the morphology of cultured bovine aortic endothelial cells is studied. Fully confluent endothelial cells cultured on glass were subjected to a fluid-imposed shear stress of 2 Pa for 20 min and 24 h using a parallel plate flow chamber. Experiments on shear flow exposure were performed fo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02522869
更新日期:1998-01-01 00:00:00
abstract::The aim of the study is to determine the effects of wound, patient and treatment attributes on the wound healing rate and to propose a system for wound healing rate prediction. Predicting the wound healing rate from the initial wound, patient and treatment data collected in a database of 300 chronic wounds is not poss...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345144
更新日期:2001-09-01 00:00:00
abstract::Spontaneous activity of specific regions (e.g., the Sinoatrial node, SAN) is essential for the normal activation sequence of the heart and also serve as a primary means of modulating cardiac rate by sympathetic tone and circulating catecholamines. The mechanisms of how a small SAN region can electrically drive a much ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-006-0102-9
更新日期:2007-02-01 00:00:00
abstract::Nowadays, acoustic emission (AE) has its applications in various areas, including mechanical, civil, underwater acoustics, and biomedical engineering. It is a non-destructive evaluation (NDE) and a non-intrusive method to detect active damage mechanisms such as crack growth, delamination, and processes such as frictio...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-020-02202-z
更新日期:2020-08-01 00:00:00
abstract::Density assessment and lesion localization in breast MRI require accurate segmentation of breast tissues. A fast, computerized algorithm for volumetric breast segmentation, suitable for multi-centre data, has been developed, employing 3D bias-corrected fuzzy c-means clustering and morphological operations. The full br...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1484-y
更新日期:2017-01-01 00:00:00
abstract::In this study, we propose an integrated tooth segmentation and gingival tissue deformation simulation framework used to design and evaluate the orthodontic treatment plan especially with invisible aligners. Firstly, the bio-characteristics information of the digital impression is analyzed quantitatively and demonstrat...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02230-9
更新日期:2020-10-01 00:00:00
abstract::Artifacts cause distortion and fuzziness in electroencephalographic (EEG) signal and hamper EEG analysis, so it is necessary to remove them prior to the analysis. Particularly, artifact removal becomes a critical issue in experimental protocols with significant inherent recording noise, such as mobile EEG recordings a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-017-1620-3
更新日期:2017-09-01 00:00:00
abstract::A method for accurately finding cardiac bidomain conductivity parameters is a crucial part of efforts to study and understand the electrical functioning of the heart. The bidomain model considers current flowing along (longitudinal) and across (transverse) sheets of cardiac fibres, as well as between these sheets (nor...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1101-2
更新日期:2013-12-01 00:00:00
abstract::When the microvascular blood perfusion in human skin is measured by photoplethysmography (PPG), infra-red light (800-960 nm) is normally used as the light source. The PPG signal, which consists of a pulsatile (AC) and a slowly fluctuating (DC) component, was studied at different optical wavelengths utilising optical f...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446295
更新日期:1991-01-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) is characterized by expiratory airflow limitation, but current diagnostic criteria only consider flow till the first second and are therefore strongly debated. We aimed to develop a data-based individualized model for flow decline and to explore the relationship between mod...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-014-1202-6
更新日期:2014-12-01 00:00:00
abstract::Sealing resistance is highly significant with respect to the electrical neuron-electrode contact because it decreases the stimulation threshold of neurons cultured on a planar micro-electrode array. A method is proposed for measurement of the sealing resistance using impedance spectroscopy. The effect of the sealing r...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02524436
更新日期:1998-09-01 00:00:00
abstract::Segmentation and classification of low-quality and noisy ultrasound images is challenging task. In this paper, a new approach is proposed for robust segmentation and classification of carotid artery ultrasound images and consequently, detecting cerebrovascular disease. The proposed technique consists of two phases, in...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1481-1
更新日期:2016-12-01 00:00:00
abstract::In the case of female breast cancer, a breast-conserving excision is often desirable. This surgery is based on preoperatively gathered MRI, mammography, and sonography images. These images are recorded in multiple patient positions, e. g., 2D mammography images in standing position with a compressed breast and 3D MRI ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-01977-0
更新日期:2019-07-01 00:00:00