Abstract：
:Density assessment and lesion localization in breast MRI require accurate segmentation of breast tissues. A fast, computerized algorithm for volumetric breast segmentation, suitable for multi-centre data, has been developed, employing 3D bias-corrected fuzzy c-means clustering and morphological operations. The full breast extent is determined on T1-weighted images without prior information concerning breast anatomy. Left and right breasts are identified separately using automatic detection of the midsternum. Statistical analysis of breast volumes from eighty-two women scanned in a UK multi-centre study of MRI screening shows that the segmentation algorithm performs well when compared with manually corrected segmentation, with high relative overlap (RO), high true-positive volume fraction (TPVF) and low false-positive volume fraction (FPVF), and has an overall performance of RO 0.94 ± 0.05, TPVF 0.97 ± 0.03 and FPVF 0.04 ± 0.06, respectively (training: 0.93 ± 0.05, 0.97 ± 0.03 and 0.04 ± 0.06; test: 0.94 ± 0.05, 0.98 ± 0.02 and 0.05 ± 0.07).
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Ertas G,Doran SJ,Leach MOdoi
10.1007/s11517-016-1484-ysubject
Has Abstractpub_date
2017-01-01 00:00:00pages
57-68issue
1eissn
0140-0118issn
1741-0444pii
10.1007/s11517-016-1484-yjournal_volume
55pub_type
杂志文章abstract：:A novel laser Doppler flowmetry scheme is reported that adjusts the processing bandwidth adaptively to optimise the estimation of flow. To obtain an adequate processing bandwidth, the Doppler spectra is first fitted to the Lorentzian function, and the bandwidth at half the maximum of the Lorentzian function is used as...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344700
更新日期：2004-05-01 00:00:00
abstract：:Based on the principle of backscattering of laser radiation from tissues, a non-invasive PC-AT based reflectance imaging technique is developed. The laser beam from a semiconductor laser operating at 670 nm is guided to the tissue site by an optical fibre. The backscattered radiation is collected by another fibre plac...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02530046
更新日期：1997-05-01 00:00:00
abstract：:Results of self-consistent analyses of cells show the possibility of temperature increases at membranes in response to a single nanosecond, high-voltage pulse, at least over small sections of the membrane. Molecular Dynamics simulations indicate that such a temperature increase could facilitate poration, which is one ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-011-0745-z
更新日期：2011-06-01 00:00:00
abstract：:A previously proposed finite element model that considers geometric and material nonlinearities and the free boundary problems that occur at the catheter tip and in the annular zone around the lateral surface of the catheter was revised and was used to fit a power-law formula to predict backflow length during infusion...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-014-1187-1
更新日期：2014-10-01 00:00:00
abstract：:A new ambulatory technique for qualitative and quantitative movement analysis of the humerus is presented. 3D gyroscopes attached on the humerus were used to recognize the movement of the arm and to classify it as flexion, abduction and internal/external rotations. The method was first validated in a laboratory settin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0464-x
更新日期：2009-05-01 00:00:00
abstract：:Partial coherence estimate between two signals removing the contribution of a periodic, deterministic one is proposed for measuring the coherence between two ongoing eletroencephalografic (EEG) activities collected at distinct cortical regions under sensory stimulation. The estimator expression was derived and shown t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0191-0
更新日期：2007-07-01 00:00:00
abstract：:In this study, the shape and the configuration of smooth muscle cells (SMCs) within the arterial wall are altered to investigate their influence on molecular transport across the media layer of the thoracic aorta wall. In a 2D geometry of the media layer containing SMCs, the finite-element method has been employed to ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0219-5
更新日期：2007-11-01 00:00:00
abstract：:Magnetoenterography (MENG) is a new, non-invasive technique that measures gastrointestinal magnetic signals near the body surface. This study was undertaken to evaluate the temporal and spatial characteristics of the magnetic signals generated by gastric and duodenal slow wave activity. The gastrointestinal magnetic f...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513347
更新日期：1999-09-01 00:00:00
abstract：:Several recent studies have quantified abnormalities in Parkinsonian gait. However, few studies have attempted to quantify the regularity of body motion during walking in patients with Parkinson's disease. The aim of the paper was to characterise body motion patterns in healthy, elderly subjects and patients with Park...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02351008
更新日期：2004-01-01 00:00:00
abstract：:Many studies concerning the internal work of human motion have used two-dimensional kinematic models to estimate kinetic energy of the segments. The generalised co-ordinate concept has been applied here to a simultaneous and bilateral gait analysis. A three-dimensional kinematic model based on quaternions has been dev...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02523852
更新日期：1996-11-01 00:00:00
abstract：:Vertebral fractures are common in children with osteogenesis imperfecta (OI). Current imaging methods for fracture detection (X-ray and DXA) use ionising radiation. This pilot study explored whether the alteration in blood flow in vertebral fractures results in skin temperature changes that may be detected using high ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1806-3
更新日期：2018-09-01 00:00:00
abstract：:A hydrodynamic model for the part of the human arterial network below the renal arteries has been constructed using specially fabricated distensible tubes and a pulsatile pump to simulate an aortoiliac bypass. The experiments and the computer model indicated that no 'steal' occurred due to the insertion of the bypass ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02441802
更新日期：1993-11-01 00:00:00
abstract：:A nonlinear prediction method for investigating the dynamic interdependence between short length time series is presented. The method is a generalization to bivariate prediction of the univariate approach based on nearest neighbor local linear approximation. Given the input and output series x and y, the relationship ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0043-3
更新日期：2006-05-01 00:00:00
abstract：:The relation is investigated between stimulus frequency, stimulus pulse amplitude and the neural damage induced by continuous stimulation of the cat's sciatic nerve. The chronically implanted electrodes were pulsed continuously and the effects of the electrical stimulation were quantified as the amount of early axonal...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02510526
更新日期：1995-05-01 00:00:00
abstract：:In a computerised ultrasound image guidance for automated prostatectomy system, it is necessary to identify a smooth, continuous contour for the prostate (boundary) from the ultrasound image. The radial bas-relief (RBR) method, which has been reported previously, can extract a skeletonised image from an ultrasound ima...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02518882
更新日期：1998-11-01 00:00:00
abstract：:Spinal pattern generators (SPGs), which are neural networks without a central input from the brain may be responsible for controlling locomotion. In this study, we used neural oscillators to examine the rhythmic patterns generated at the ankle during walking. Seven healthy male subjects were requested to walk at their...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-012-0944-2
更新日期：2012-09-01 00:00:00
abstract：:Electrical and mechanical stimulation of the oesophagus has been recently proposed to examine the physiological effects of autonomic stimulation in humans. Cortical evoked potentials (EPs) to oesophageal stimulation provide an assessment of afferent fibres and central processing. However, habituation takes place durin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02534088
更新日期：1997-07-01 00:00:00
abstract：:Calcific aortic valve disease (CAVD) is characterized by calcification accumulation and thickening of the aortic valve cusps, leading to stenosis. The importance of fluid flow shear stress in the initiation and regulation of CAVD progression is well known and has been studied recently using fluid-structure interaction...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1458-0
更新日期：2016-11-01 00:00:00
abstract：:A simple inertial measurement unit (IMU) incorporating rate gyroscopes and accelerometers has been tested to investigate the trunk kinematics during the sit-to-stand. It was affixed at trunk L5 level and used for sit-to-stand position and orientation reconstruction. The method was validated with standard optoelectroni...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0224-8
更新日期：2007-10-01 00:00:00
abstract：:Even though the World Health Organization criteria's for classifying the dengue infection have been used for long time, recent studies declare that several difficulties have been faced by the clinicians to apply these criteria. Accordingly, many studies have proposed modified criteria to identify the risk in dengue pa...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0561-x
更新日期：2010-03-01 00:00:00
abstract：:Hepatic echinococcosis (HE) is a life-threatening liver disease caused by parasites that requires a precise diagnosis and proper treatments. To assess HE lesions accurately, we propose a novel automatic HE lesion segmentation and classification network that contains lesion region positioning (LRP) and lesion region se...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02126-8
更新日期：2020-03-01 00:00:00
abstract：:To explore the promising therapeutic applications of short nanosecond electric pulses, in vitro and in vivo experiments are highly required. In this paper, an exposure system based on monopole patch antenna is reported to perform in vivo experiments on newborn mice with both monopolar and bipolar nanosecond signals. A...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1547-0
更新日期：2017-07-01 00:00:00
abstract：:Transcranial magnetic stimulation (TMS) allows the assessment of stroke patients' cortical excitability and corticospinal tract integrity, which provide information regarding motor function recovery. However, the extraction of features from motor-evoked potentials (MEP) elicited by TMS, such as amplitude and latency, ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-021-02315-z
更新日期：2021-01-26 00:00:00
abstract：:The performance of the stimulation coil in a magnetic nerve stimulator can be improved by attaching a ferromagnetic structure to the coil. This reduces heat generation at the coil and increases magnetic field strength for a given unit of current. Some technical aspects of the design of a stimulation coil with a ferrom...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345312
更新日期：2003-09-01 00:00:00
abstract：:The software system GASepo has been developed as a tool to visualise and analyse doping (searching for performance-enhancing drugs in sports) with recombinant erythropoietin (rEpo). Digital images derived from the separation of Epo isoforms in gels by iso-electric focusing followed by double blotting and chemiluminesc...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345819
更新日期：2005-05-01 00:00:00
abstract：:When the rib cage and abdomen are compressed during cardiopulmonary resuscitation (CPR), the effect on intrathoracic pressure, and therefore on haemodynamics, cannot be quantitatively predicted without a physiologically based mathematical model of chest wall dynamics. Using such a model, we compared model simulations ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02441676
更新日期：1990-01-01 00:00:00
abstract：:A new method of quantifying dermal perfusion on a regional basis using a dynamic thermographic technique is investigated. The technique is based on the relationship between dermal perfusion and the rate of skin surface reheating following the application of a transient cold challenge predicted by a theoretical model. ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02441468
更新日期：1989-09-01 00:00:00
abstract：:Successful identification of gastric slow waves in canine gastric electrical activity (GEA) data was achieved using a statistical data-processing procedure based on the multiple linear regression (MLR) curve fitting technique. Both distal and proximal waveforms were identified, first by construction of separate orthon...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345076
更新日期：2002-07-01 00:00:00
abstract：:Biological variation in branching patterns is likely to affect perfusion of tissue. To assess the fundamental consequences of branching characteristics, 50 stochastic asymmetrical coronary trees and one non-stochastic symmetrical branching tree were generated. In the stochastic trees, area growth, A, at branching poin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0139-9
更新日期：2007-01-01 00:00:00
abstract：:Neurofilaments are organised into parallel bundles in axons through crossbridges formed by lateral projections of neurofilament subunits. Pure neurofilaments form gels in vitro, consisting of interconnected parallel arrays of filaments regulated by the phosphorylation level of neurofilament subunits. Neurofilament-ass...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02522486
更新日期：1998-05-01 00:00:00
