Association between polymorphisms of interleukin-17A G197A and interleukin-17F A7488G and risk of colorectal cancer.

abstract：AIM OF STUDY:To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver nanoparticles (SNs) to tumor growth in a murine model. MATERIALS AND METHODS:Sanazole (AK) and DOX were complexed with SNs, individually and in combination to obtain SN-AK, SN-DOX, and SN-AK-DOX....

journal_title：Journal of cancer research and therapeutics

authors： Nair GG,Nair CK

更新日期：2014-10-01 00:00:00

abstract：Aim:The aim of this study is to identify an ideal location of isocenter in intensity-modulated radiotherapy (IMRT) treatment plans. Materials and Methods:A total of 28 clinical target volumes and 4 English capital letters (C, L, T, and H) target volumes were considered in this study. Two IMRT treatment plans were gene...

journal_title：Journal of cancer research and therapeutics

authors： Mandal A,Asthana AK,Pradhan S,Shahi UP,Choudhary S

更新日期：2019-01-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a group of sarcomas that exhibit a myomelanocytic phenotype and possess a unique cell type in the perivascular epithelioid cell. Traditionally HMB-45 immunoreactivity is the first criteria required to consider a tumor to be PEComa. We report a case of multifocal PEComa w...

journal_title：Journal of cancer research and therapeutics

authors： Kapoor A,Beniwal S,Singhal MK,Kumar N,Kumar V,Kumar HS

更新日期：2015-10-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a common cancer world-wide with a higher incidence in Asia. Clear cell variant of HCC (CCHCC) has a frequency ranging from 0.4% to 37%. The presence of 90-100% clear cells is rare. In the present case, a 35-year-old female patient presented with fever and a large abdominal mass in the...

journal_title：Journal of cancer research and therapeutics

authors： Sakhuja P,Mishra PK,Rajesh R,Sharma AK,Gondal R,Singh M

更新日期：2015-07-01 00:00:00

abstract：Aim:Tumor-associated macrophages (TAMs) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis, and immune functions within tumor microenvironments. Tumor progression is frequently associated with a phenotypic switch from M1 to M2 in TAM. Activation of signal transdu...

journal_title：Journal of cancer research and therapeutics

authors： Seyedi Z,Hashemzadeh MR,Colagar AH,Jaafari MR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Changes in salivary flow rate were studied in head and neck (H and N) cancer patients who, after receiving moderately accelerated radiotherapy (RT) and concurrent chemotherapy (CT), were free of disease at 1 year. MATERIALS AND METHODS:Between July 2003 and July 2005, saliva estimation was performed for 36 ...

journal_title：Journal of cancer research and therapeutics

authors： Lal P,Bajpai R,Khurana R,Das KJ,Kumar P,Tiwari A,Gupta N,Kumar S

更新日期：2010-10-01 00:00:00

abstract：AIM OF STUDY:The aim of this study was to analyze the clinical features and outcomes of thyroid carcinoma (TC) in children and adolescent population treated in our institution. MATERIALS AND METHODS:We gathered 43 TC patients 18 years of age or under initial diagnosed between 2009 and 2010 from two hospitals. Patient'...

journal_title：Journal of cancer research and therapeutics

authors： Pan JJ,Zhao L,Cheng R,Yang Y,Hu YH

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:The oncogenic form of anaplastic lymphoma kinase (ALK) gene is an attractive candidate marker for diagnostic and therapeutic purposes in several malignancies, including nonsmall cell lung cancer (NSCLC). This study aimed to examine the expression levels and clinical significance of ALK in a series of NSCLC...

journal_title：Journal of cancer research and therapeutics

authors： Roudi R,Haji G,Madjd Z,Shariftabrizi A,Mehrazma M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Lung cancer is the leading cause of cancer-related death worldwide, and the number of elderly patients with nonsmall-cell lung cancer (NSCLC) has risen with increasing life-expectancy. AIMS:To evaluate safety and efficacy of thoracoscopic lobectomy for NSCLC patients above 75 years old. PATIENTS AND METHOD...

journal_title：Journal of cancer research and therapeutics

authors： Qiang G,Liang C,Guo Y,Shi B,Tian Y,Song Z,Liu D

更新日期：2015-10-01 00:00:00

abstract：CONTEXT:The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1), which has been isolated from dried Antrodi...

journal_title：Journal of cancer research and therapeutics

authors： Wei PL,Tu SH,Lien HM,Chen LC,Chen CS,Wu CH,Huang CS,Chang HW,Chang CH,Tseng H,Ho YS

更新日期：2012-10-01 00:00:00

abstract：:Prostate cancer, one of the most common male malignancies with an increasing incidence in the recent years, requires the development of new methods of treatment. One of the most debated subjects is the tumor-associated macrophages (TAM). Although, the pathophysiological mechanisms are still a subject of intense resear...

journal_title：Journal of cancer research and therapeutics

authors： Nenu I,Gafencu GA,Popescu T,Kacso G

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

journal_title：Journal of cancer research and therapeutics

authors： Chen HH,Wang QY,Zhou SH

更新日期：2016-01-01 00:00:00

abstract：Background:Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Materials and Methods:Kyoto E...

journal_title：Journal of cancer research and therapeutics

authors： Yu B,Li T,Chen J,Wang FQ,Fu JH,Liu SM,Wang Y,Zhang X,Yang HT

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To study the clinical results and prognostic factors of patients with glioblastoma multiforme (GBM) treated by postoperative radiation therapy (PORT) and concomitant temozolomide followed by adjuvant temozolomide. METHODS:From 2005 to 2008, 215 patients (median age 48 years) with GBM were treated with PORT p...

journal_title：Journal of cancer research and therapeutics

authors： Julka PK,Sharma DN,Mallick S,Gandhi AK,Joshi N,Rath GK

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Adenoid cystic carcinoma (ACC) is malignant neoplasm of the salivary glands. It accounts for most cases of minor salivary gland malignancies and a substantial proportion of parotid and submandibular gland malignancies. ACC is associated with a high mortality rate, and it often recurs after prolonged period...

journal_title：Journal of cancer research and therapeutics

authors： Jain A,Shetty DC,Rathore AS,Kumar K

更新日期：2016-04-01 00:00:00

abstract：:A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...

journal_title：Journal of cancer research and therapeutics

authors： Sayit AT,Elmali M,Gul A,Sullu Y

更新日期：2019-07-01 00:00:00

abstract：AIMS:Several studies suggested that systemic lupus erythematosus (SLE) were associated with the risk of lung cancer. However, other studies did not confirm the result. Therefore, we conducted a meta-analysis to investigate this association. MATERIALS AND METHODS:A systematic literature search was conducted using the P...

journal_title：Journal of cancer research and therapeutics

authors： Wu Y,Hou Q

更新日期：2016-04-01 00:00:00

abstract：:We report a known case of adenoid cystic carcinoma of right parotid gland in a 36-year-old Indian male, diagnosed 5 years ago for which he underwent surgery followed by radiotherapy. Now the patient has presented to the surgical oncologist with a mass near angle of right jaw. Computed tomography (CT) performed elsewhe...

journal_title：Journal of cancer research and therapeutics

authors： Tewari A,Padma S,Sundaram PS

更新日期：2013-01-01 00:00:00

abstract：:A 29-year-old hypertensive male with von Hippel-Lindau (VHL) syndrome came to the Endocrinology department for evaluation. Contrast-enhanced computed tomography of the abdomen revealed an adrenal mass, bilateral renal cell carcinoma, and multiple pancreatic cysts. The hormonal investigations for adrenal mass were norm...

journal_title：Journal of cancer research and therapeutics

authors： Palui R,Kamalanathan S,Sahoo J,Dorairajan LN,Badhe B,Gochhait D

更新日期：2019-03-01 00:00:00

abstract：CONTEXT:The pepino fruit Solanum muricatum Ait. (Solanaceae) is commonly known as melon pear and sweet cucumber grown in South America, New Zealand, and India. Traditionally, the fruits are used in the treatment of diabetes and cancer. AIM:The objective of present study is to explore the immunomodulatory, anticancer, ...

journal_title：Journal of cancer research and therapeutics

authors： Shathish K,Guruvayoorappan C

更新日期：2014-07-01 00:00:00

abstract：Background:To evaluate the usefulness of preoperative imaging with F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) for noninvasive risk assessment of gastrointestinal stromal tumor (GIST). Materials and Methods:A retrospective review including 32 patients with pathologically proven GIST. Preoperative FD...

journal_title：Journal of cancer research and therapeutics

authors： Kwon Y,Park E,Pahk K,Kim S,Kim MJ,Graf D,Park S

更新日期：2019-01-01 00:00:00

abstract：Objective:Conflicting data have been reported regarding the association between perioperative blood transfusion (PBT) and clinical outcomes for prostate cancer patients. We conducted a systematic review and meta-analysis to evaluate the impact of PBT on cancer survival and recurrence for patients who underwent radical ...

journal_title：Journal of cancer research and therapeutics

authors： Pushan Z,Manbiao C,Sulai L,Jun L,Ruidong Z,Hanshen Y

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Clinical significance of chloride intracellular channel 1 (CLIC1) in pancreatic ductal adenocarcinomas (PDAC) remains largely unknown. This study was performed to assess the expression of CLIC1 in benign and malignant pancreatic lesions, and to assess its clinicopathological significance. MATERIALS AND METH...

journal_title：Journal of cancer research and therapeutics

authors： Jia N,Dong S,Zhao G,Gao H,Li X,Zhang H

更新日期：2016-04-01 00:00:00

abstract：AIMS:To evaluate current focal high precision radiotherapy (RT) techniques to spare hippocampi most optimally, in view of mounting clinical evidence to preserve neurocognition. MATERIALS AND METHODS:Computed tomography/magnetic resonance imaging (CT/MRI) datasets of 10 patients with benign/low-grade brain tumors, trea...

journal_title：Journal of cancer research and therapeutics

authors： Kothavade V,Jamema SV,Gupta T,Pungavkar S,Upasani M,Juvekar S,Jalali R

更新日期：2015-04-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) a member of the heat shock proteins (HSPs) family, is an adenosine triphosphate dependent molecular chaperone protein, which integrates multiple oncogenic pathways. Clinically, encouraging results have been demonstrated in melanoma, acute myeloid leukemia, castrate refractory prostate can...

journal_title：Journal of cancer research and therapeutics

authors： Routray S,Sunkavalli A,Swain N,Shankar AA

更新日期：2013-10-01 00:00:00

abstract：:Lymphoproliferative malignancies can involve both nodal- and extra-nodal tissues. The most common extranodal site involved is the gastrointestinal (GI) tract, and it is secondary to the widespread primary nodal disease. However, about 33% of non-Hodgkin's lymphoma primarily arise from tissues other than lymph nodes, s...

journal_title：Journal of cancer research and therapeutics

authors： Modi V,Bajaj N,Lakkasani S,Shaaban HS,Guron G

更新日期：2020-01-01 00:00:00

abstract：Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

journal_title：Journal of cancer research and therapeutics

authors： Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

更新日期：2019-10-01 00:00:00

abstract：:Masseter hypertrophy is a characteristic condition resulting from an increase in the size of the muscle mass. At times, it produces significant facial asymmetry and is an important finding in the differential diagnosis of similar located entities. A proper diagnosis of this condition would avoid more aggressive and un...

journal_title：Journal of cancer research and therapeutics

authors： Naphade VV,Kedia SG,Patil P,Khare S

更新日期：2018-12-01 00:00:00