Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.

abstract：PURPOSE:This retrospective study aims to assess the cut-off value of thyroglobulin (Tg) levels in nux or metastatic well-differentiated thyroid cancers (DTCs) with normal anti-Tg levels using with fluorodeoxyglucose/positron emission tomography/computed tomography (FDG PET/CT). MATERIALS AND METHODS:We reviewed FDG PE...

journal_title：Journal of cancer research and therapeutics

authors： Döner RK,Sager S,Görtan FA,Topuz ÖV,Akyel R,Vatankulu B,Baran A,Teksoz S,Sönmezoglu K

更新日期：2016-04-01 00:00:00

abstract：:Basal cell adenoma (BCA) of the salivary glands is an uncommon type of monomorphic adenoma which constitutes 1% of all salivary gland tumors. It most commonly involves parotid gland, while it rarely occurs in minor salivary glands. Upper lip, buccal mucosa, and lower lip are the common intraoral sites; whereas, palate...

journal_title：Journal of cancer research and therapeutics

authors： Sodhi SP,Brar RS,Singh HP,Kaur T,Dhawan R

更新日期：2015-10-01 00:00:00

abstract：:Primary amyloidosis of bladder is a rare disease that closely resembles bladder cancer on clinical presentation with painless gross hematuria. Pathologically this is a totally benign non-neoplastic lesion and its association with urothelial carcinoma of the bladder is rare. We herein report a 64-year-old diabetic male...

journal_title：Journal of cancer research and therapeutics

authors： Gupta P,Hanamshetti S,Kulkarni JN

更新日期：2012-04-01 00:00:00

abstract：Purpose:Papillary thyroid carcinoma (PTC) has a strong propensity to metastasize to regional lymph nodes which increases the risk of local-regional relapse and affects the course of the disease. Molecular pathogenesis of lymph node metastasis (LNM) is not yet fully understood. Survivin, a multifunctionale molecule invo...

journal_title：Journal of cancer research and therapeutics

authors： Selemetjev S,Savin S,Paunovic I,Tatic S,Cvejic D

更新日期：2018-01-01 00:00:00

abstract：:Doxorubicin (Adriamycin, ADM) is an antimitotic drug used in the treatment of a wide range of malignant tumors, including acute leukemia, lymphoma, osteosarcoma, breast cancer, and lung cancer. Multidrug resistance-associated proteins (MRPs) are members of a superfamily of ATP-binding cassette (ABC) transporters, whic...

journal_title：Journal of cancer research and therapeutics

authors： He Z,Hu B,Tang L,Zheng S,Sun Y,Sheng Z,Yao Y,Lin F

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Tumor markers are a major part of the secondary prevention and thus the detection of malignancies. Neoplasms often have an increased concentration of sialic acid on the tumor cell surface and are shed or secreted by some of these cells which increase the concentration in blood. MATERIALS AND METHODS:The stu...

journal_title：Journal of cancer research and therapeutics

authors： Joshi M,Patil R

更新日期：2010-07-01 00:00:00

abstract：:Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...

journal_title：Journal of cancer research and therapeutics

authors： Valecha J,Ojha SS,Sharma A,Nilkanthe R

更新日期：2019-01-01 00:00:00

abstract：Objectives:Increasing evidence suggests that Wnt5a plays an important role in tumorigenesis. In particular, its expression is downregulated in hepatocellular carcinoma (HCC). The aim of this study was to explore the effect of Wnt5a overexpression on HCC cells. Materials and Methods:We transfected the human HCC cell li...

journal_title：Journal of cancer research and therapeutics

authors： Wang T,Liu X,Wang J

更新日期：2019-01-01 00:00:00

abstract：AIM:The discipline of radiotherapy (RT) in India is considered a low priority subject. Postgraduate (PG) students rarely choose RT as a career option. The possible reasons could be: 1) limited availability of PG course training centers, 2) limited job prospects, etc. We decided to conduct a survey of undergraduate (UG)...

journal_title：Journal of cancer research and therapeutics

authors： Sharma DN,Rath GK,Parashar A,Singh P

更新日期：2010-01-01 00:00:00

abstract：:Follow-up of colorectal carcinoma after therapy is based on symptoms, tumor markers, and imaging studies. Clinicians sometimes face diagnostic dilemmas because of unusual presentations on the imaging modalities coupled with rising serum markers. We report a case of colorectal carcinoma that presented with gastrointest...

journal_title：Journal of cancer research and therapeutics

authors： Joshi SC,Pant I,Shukla AN,Anshari MA

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To explore the outcome and prognostic factors of recursive partitioning analysis (RPA) Class III brain metastatic patients treated with stereotactic radiotherapy (SRT). MATERIALS AND METHODS:Fifty-six consecutive patients with metastatic brain tumors and Karnofsky performance scale (KPS) scores <70 treated w...

journal_title：Journal of cancer research and therapeutics

authors： Chen XJ,Xiao JP,Li XP,Jiang XS,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:Complementary and alternative medicine (CAM) use among cancer patients is widely prevalent and often underreported. Advanced stage of disease is significantly associated with CAM use. The concurrent use of alternative medicines and chemotherapy drugs has the potential to lead to toxicities as well as altered therapeut...

journal_title：Journal of cancer research and therapeutics

authors： Gulia S,Gota V,Kumar SD,Gupta S

更新日期：2015-10-01 00:00:00

abstract：:Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. ...

journal_title：Journal of cancer research and therapeutics

authors： Varnali E,Kavak A,Özkan Y,Karahacioglu FB

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：Objective:This study aimed to explore the risk factors of hepatocellular carcinoma (HCC) and survival analysis for cirrhosis after transjugular intrahepatic portosystemic shunt (TIPS) in treating portal hypertension. Materials and Methods:A retrospective database review was performed, including 106 patients (33 female...

journal_title：Journal of cancer research and therapeutics

authors： Wei J,Li H,Li C

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Prostate-specific membrane antigen (PSMA) is a widely used targeted molecule in prostate patients. The present research, attempts to support the hypothesis that PSMA expression in prostate cancer stem cell-like (CSC) cell populations may be correlated with nanog and other transcription factors in different s...

journal_title：Journal of cancer research and therapeutics

authors： Maria T,Panagiotis A,Marina C,Eleni K,Ioanna V,Georgia M,Ioannis P

更新日期：2014-01-01 00:00:00

abstract：:Adenoid cystic carcinomas (ACC) of the head and neck are relatively rare tumors, consisting of approximately 10-15% of all salivary gland neoplasms. ACC, a slow-growing aggressive malignant tumor of salivary gland commonly seen in the submandibular, sublingual, minor salivary glands is seldom found in the parotid. Cal...

journal_title：Journal of cancer research and therapeutics

authors： Shenoy VS,Kamath MP,Sreedharan S,Suhas SS

更新日期：2015-07-01 00:00:00

abstract：AIM OF THE STUDY:In the present study the effects of mangiferin were tested against lung cancer-bearing mice in both the pre-initiation and post-initiation periods. MATERIALS AND METHODS:Healthy male Swiss albino mice (6-8 weeks old) were used throughout the study. The animals were treated with mangiferin (100 mg/kg b...

journal_title：Journal of cancer research and therapeutics

authors： Rajendran P,Rengarajan T,Nishigaki I,Ekambaram G,Sakthisekaran D

更新日期：2014-10-01 00:00:00

abstract：AIM OF STUDY:To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver nanoparticles (SNs) to tumor growth in a murine model. MATERIALS AND METHODS:Sanazole (AK) and DOX were complexed with SNs, individually and in combination to obtain SN-AK, SN-DOX, and SN-AK-DOX....

journal_title：Journal of cancer research and therapeutics

authors： Nair GG,Nair CK

更新日期：2014-10-01 00:00:00

abstract：:The present case report defines a rare case of a liposarcoma with bone metastasis resulting in a complete remission (CR) following trabectedin treatment. The patient was referred with abdominal swelling and pain. A retroperitoneal mass was detected and described as dedifferentiated liposarcoma (DDLS). The mass was sur...

journal_title：Journal of cancer research and therapeutics

authors： Kus T,Aktas G,Kalender ME,Tutar E,Ulker E,Camci C

更新日期：2015-10-01 00:00:00

abstract：Background:Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Materials and Methods:Kyoto E...

journal_title：Journal of cancer research and therapeutics

authors： Yu B,Li T,Chen J,Wang FQ,Fu JH,Liu SM,Wang Y,Zhang X,Yang HT

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Malignant fibrous histiocytoma (MFH) is an uncommon neoplasm of maxillary sinus. This study was designed to investigate the clinical courses and summarize the experience of the treatment outcomes. MATERIALS AND METHODS:This is a retrospective analysis which included patients with MFH of the maxillary sinus ...

journal_title：Journal of cancer research and therapeutics

authors： Huang H,Li D,Wang X,Wu Y,Liu S,Xu Z

更新日期：2017-01-01 00:00:00

abstract：Background:Interleukin (IL)-17A and IL-17F are inflammatory cytokines mainly produced by T helper 17 cells. IL-17A is known to be protumorigenic while IL-17F has a protective role in cancer. A number of studies have been conducted to determine the association between polymorphisms of IL-17AG197A (rs2275913) and IL-17FA...

journal_title：Journal of cancer research and therapeutics

authors： Samiei G,Yip WK,Leong PP,Jabar MF,Dusa NM,Mohtarrudin N,Seow HF

更新日期：2018-06-01 00:00:00

abstract：:A rare and unique variant of breast cancer--metaplastic matrix producing carcinoma, is presented. Surgery has been the mainstay of treatment. The role of adjuvant postoperative radiotherapy, as has been used in this patient, has been reviewed. ...

journal_title：Journal of cancer research and therapeutics

authors： Kumar P,Agarwal T,Krishnani N,Singh S,Datta NR

更新日期：2006-04-01 00:00:00

abstract：:A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...

journal_title：Journal of cancer research and therapeutics

authors： Sayit AT,Elmali M,Gul A,Sullu Y

更新日期：2019-07-01 00:00:00

abstract：Objective:This study investigated the association between abnormal matrix metalloproteinase-9 (MMP-9) expression and bladder cancer (BC) development. Materials and Methods:In a retrospective analysis, this study used tissue samples derived from 92 patients pathologically diagnosed with BC (experimental group), who wer...

journal_title：Journal of cancer research and therapeutics

authors： Wu GJ,Bao JS,Yue ZJ,Zeng FC,Cen S,Tang ZY,Kang XL

更新日期：2018-01-01 00:00:00

abstract：AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...

journal_title：Journal of cancer research and therapeutics

authors： Yilmaz U,Yılmaz U,Yasar Z,Kıraklı EK,Ulger S,Ozdogan Y,Demirci NY,Erol S,Ozdogan I,Sahin B,Koksal D,Akcay C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Bleomycin-induced pulmonary (BIP) toxicity is a notorious entity and cropped up in roughly 10% of cases. The aim of the study is to evaluate BIP at our tertiary care cancer center. PATIENTS AND METHODS:This is a retrospective, analytical study conducted at a tertiary care center from January 1998 to Decembe...

journal_title：Journal of cancer research and therapeutics

authors： Madabhavi I,Modi G,Patel A,Anand A,Panchal H,Parikh S

更新日期：2017-07-01 00:00:00

abstract：Introduction:The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established. We perform a single institutional retrospective study of CRT in terms of toxicity in elderly patients (age more than 60 years) as compared with young cohort (age <60 years)...

journal_title：Journal of cancer research and therapeutics

authors： Mohata S,Kumar HS,Sharma N,Jhakhar SL,Beniwal S,Harsh KK

更新日期：2020-01-01 00:00:00

abstract：:Often in metastatic disease, biopsy confirmation of suspicious central nervous system (CNS) lesions is not mandated according to the American College of Radiology, International Radiosurgery Association, and the National Comprehensive Cancer Network. We present a case of an individual who was thought to have metastati...

journal_title：Journal of cancer research and therapeutics

authors： Gestaut MM,Strober ED,Jhavar SG,Patel MK

更新日期：2017-10-01 00:00:00