abstract：Purpose:Programmed death ligand-1 (PD-L1) is the main ligand for programmed death-1 (PD-1), and is one of the major targets for cancer immunotherapy. Only a few studies are available for the clinical significance of PD-1/PD-L1 in nasopharyngeal carcinoma (NPC). There is a controversial association between PD-L1 express...

journal_title：Journal of cancer research and therapeutics

authors： Sahinli H,Akyürek N,Yılmaz M,Kandemir O,Duran AO,Kulaçoǧlu S,Uçar G,Acar E,Özet A,Öksüzoǧlu OBÇ,Özdemir NY

更新日期：2020-12-01 00:00:00

abstract：Background:Intractable ascites secondary to malignant disease deteriorates patients' quality of life. The purpose of this study was to evaluate the safety and efficacy of percutaneous peritoneovenous (Denver) shunt in treating intractable malignant ascites in cancer patients. Materials and Methods:Thirty-five patients...

journal_title：Journal of cancer research and therapeutics

authors： Tamagawa H,Aoyama T,Inoue H,Fujikawa H,Sawazaki S,Numata M,Sato T,Oshima T,Yukawa N,Morimoto M,Ueno M,Rino Y,Masuda M

更新日期：2020-12-01 00:00:00

abstract：Introduction:Human papillomavirus (HPV) is emerging as a risk factor for esophageal squamous carcinoma. The prognostic value of the HPV status has been investigated. However, the results are much controversial. Aim:This study aims to document the association of HPV infection and mutation of p53 gene in esophageal squa...

journal_title：Journal of cancer research and therapeutics

authors： Singh T,Shirazi N,Bansal S,Gupta M,Saini S,Ahmad M

更新日期：2020-12-01 00:00:00

abstract：Aim:This study was carried out to determine the fungal profile and antifungal susceptibility pattern in the brushing samples of candidiasis in patients with carcinoma of esophagus. Materials and Methods:The study was carried out in the Departments of Microbiology and Surgical Oncology of a regional cancer center from ...

journal_title：Journal of cancer research and therapeutics

authors： Talukdar A,Barman R,Sarma A,Krishnatreya M,Sharma JD,Kataki AC

更新日期：2020-12-01 00:00:00

abstract：Purpose:We want to compare the synergistic effect of low-intensity, dual-frequency (dual) ultrasound (US), applied in a repetitive sonication mode, and acoustically active lipospheres (AALs) containing doxorubicin (DOX) in a murine model (Balb/C). Subjects and Methods:The tumor-bearing mice were divided into nine grou...

journal_title：Journal of cancer research and therapeutics

authors： Soleimani H,Abdolmaleki P,Mokhtari-Dizaji M,Toliat T,Tavasoly A

更新日期：2020-10-01 00:00:00

abstract：Background:Role of hypofractionated radiotherapy (HFRT) in early breast cancer is established; comparatively, there are limited data for HFRT in locally advanced breast cancer (LABC). We report the impact of HFRT in unselected breast cancer patients in comparison with historically treated patients with conventional fra...

journal_title：Journal of cancer research and therapeutics

authors： Yadav R,Lal P,Agarwal S,Misra S,Verma M,Das KJM,Senthil Kumar SK,Kumar A,Mishra SK,Agarwal A,Agarwal G,Mishra A,Chand G,Verma AK,Kumar S

更新日期：2020-10-01 00:00:00

abstract：Aims:This study is carried out to report on the knowledge and practice regarding breast self-examination (BSE) among women from the city of Mosul in Iraq and to evaluate the prevalence of performing clinical breast examination (CBE) and mammography among them. Settings and Design:A descriptive, cross-sectional survey ...

journal_title：Journal of cancer research and therapeutics

authors： Al-Qazaz HK,Yahya NA,Ibrahim DK

更新日期：2020-10-01 00:00:00

abstract：Background:Initiation, promotion, progression, and metastasis of mammary tumors are mediated by dysregulation of multiple genes involved in various signaling pathways. Expressional variation of these molecules significantly influences cancer cell proliferation in breast cancer. Aims and Objectives:In the current study...

journal_title：Journal of cancer research and therapeutics

authors： Qadir J,Riaz SK,Sahar NE,Aman D,Khan MJ,Malik MFA

更新日期：2020-10-01 00:00:00

abstract：Background:Lung cancer is the leading cause of cancer-related deaths worldwide. The high resistance of this type of cancer to radiotherapy and chemotherapy is the greatest challenge for the complete eradication of cancer cells. Although the combination of chemotherapeutic agents has some promising results, severe side ...

journal_title：Journal of cancer research and therapeutics

authors： Kahkesh MH,Salehi Z,Najafi M,Ghobadi A,Izad M,Shirazi A

更新日期：2020-10-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.188431]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2020-10-01 00:00:00

abstract：Objective:The aim of this study is to investigate the application and the feasibility of microwave ablation in laparoscopic partial splenectomy. Materials and Methods:From January 2018 to June 2019, four patients with benign spleen lesions in our hospital underwent laparoscopic partial splenectomy assisted by microwav...

journal_title：Journal of cancer research and therapeutics

authors： Li Q,Liu Z,Hu M,Ou M,Liu K,Lin W,Wu F,Cao M

更新日期：2020-09-01 00:00:00

abstract：Aims:The role of prophylactic central neck dissection (CND) in the management of papillary thyroid carcinoma (PTC) is controversial. This study reports outcomes of an observational approach in PTC patients without clinical evidence of lymph node metastasis. Materials and Methods:Patients with PTC who had surgery (with...

journal_title：Journal of cancer research and therapeutics

authors： Huang H,Wu L,Liu W,Liu J,Liu Y,Xu Z

更新日期：2020-09-01 00:00:00

abstract：Objective:The hemoglobin, albumin, lymphocyte, and platelet (HALP) score, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are the important prognostic markers in some tumor types. This study aimed to evaluate the prognostic impact of pretreatment using HALP, NLR, and PLR for patients with s...

journal_title：Journal of cancer research and therapeutics

authors： Yang N,Han X,Yu J,Shu W,Qiu F,Han J

更新日期：2020-09-01 00:00:00

abstract：:Camrelizumab is a programmed death receptor-1 inhibitor originally developed in China for the treatment of refractory lymphoma. It has also been effective in non-small-cell lung cancer patients. However, the rechallenge of camrelizumab was not reported previously. We report the rechallenge of camrelizumab therapy in t...

journal_title：Journal of cancer research and therapeutics

authors： Wei Z,Yang X,Ye X

更新日期：2020-09-01 00:00:00

abstract：Purpose:The purpose of this study was to evaluate the organs at risk (OARs) doses for lung tumors in gated radiotherapy (RT) compared to conventional RT using the four-dimensional extended cardiac-torso (4D-XCAT) digital phantom in a simulation study. Materials and Methods:4D-XCAT digital phantom was used to create 32...

journal_title：Journal of cancer research and therapeutics

authors： Shahzadeh S,Gholami S,Aghamiri SMR,Mahani H,Nabavi M

更新日期：2020-07-01 00:00:00

abstract：Background:Lung adenocarcinoma has increased incidence over the past years and is the cause for almost 50% of deaths attributable to lung cancer. The objective of this paper is to identify activated pathways associated with lung adenocarcinoma based on gene co-expression network analysis. Materials and Methods:Kyoto E...

journal_title：Journal of cancer research and therapeutics

authors： Yu B,Li T,Chen J,Wang FQ,Fu JH,Liu SM,Wang Y,Zhang X,Yang HT

更新日期：2020-07-01 00:00:00

abstract：Background:Ghrelin plays a role in mechanisms related to cancer progression - including cell proliferation, invasion and migration, and resistance to apoptosis in the cell lines from several cancers. We investigated the role of ghrelin levels in cancer cachexia-anorexia in patients with locally advanced nonsmall-cell l...

journal_title：Journal of cancer research and therapeutics

authors： Uysal P,Afsar CU,Sozer V,Inanc B,Agaoglu F,Gural Z,Fazlıoglu NY,Cuhadaroglu C,Uzun H

更新日期：2020-07-01 00:00:00

abstract：:Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. ...

journal_title：Journal of cancer research and therapeutics

authors： Varnali E,Kavak A,Özkan Y,Karahacioglu FB

更新日期：2020-07-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：Introduction:Cytokeratin fragment 21-1 (CYFRA21-1), a constituent of the intermediate filament protein is known to be elevated in cancer. In vitro cleavage of cytokeratin 19 (CK19) protein results in the release of it's fragments into the supernatants of premalignant cell lines. This study was designed with the aim to ...

journal_title：Journal of cancer research and therapeutics

authors： Rathore AS,Katyal S,Jain A,Shetty DC

更新日期：2020-04-01 00:00:00

abstract：Aim of the Study:Both matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) is involved in degradation of extracellular matrix and found to stimulate invasion and metastasis in cancer patients. However, studies on the stage-specific expression of MMPs at different stages of larynx carcinoma are stil...

journal_title：Journal of cancer research and therapeutics

authors： Bakshi J,Goyal AK,Singh V,Sannigrahi M,Khullar M

更新日期：2020-04-01 00:00:00

abstract：Aims:This study aims at assessing the volume changes that occur in the targets (gross tumor volume and planning target volume [PTV]) and the organs at risk in squamous cell carcinoma of the head and neck during radiotherapy and assessing the dose changes that occur as a result of them. Settings and Design:This was a p...

journal_title：Journal of cancer research and therapeutics

authors： Ilangovan B,Venkatraman M,Balasundaram S

更新日期：2020-04-01 00:00:00

abstract：:The novel coronavirus (COVID-19) pandemic has disrupted healthcare delivery across the globe. Cancer patients are at a higher risk of acquiring this infection due to their immunosuppressed state. Timely care of patients while ensuring safety of healthcare workers is need of the hour. We list few precautionary measures...

journal_title：Journal of cancer research and therapeutics

authors： Mummudi N,Tibdewal A,Ghosh-Laskar S,Agarwal JP

更新日期：2020-04-01 00:00:00

abstract：:Acinic cell carcinoma (ACC) is a low-grade malignant salivary gland neoplasm that comprises approximately 17% of primary salivary gland malignancies or about 6% of all salivary gland neoplasms. The most common intraoral sites are the buccal mucosa, lips, and palate. The diagnosis of ACC frequently presents difficultie...

journal_title：Journal of cancer research and therapeutics

authors： Babu SS,Sunil S,Prathap A,Mathew AL

更新日期：2020-04-01 00:00:00

abstract：Aims:The goal of this study was to analyze the puncture routes of imaging-guided thermal ablation for tumors of the hepatic caudate lobe. Materials and Methods:The imaging-guided thermal ablation puncture routes of 12 cases of hepatic caudate lobe tumors were collected in our hospital from January 2013 to February 201...

journal_title：Journal of cancer research and therapeutics

authors： Yan Y,Lin ZY,Chen J

更新日期：2020-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Currently, the main effective treatment options for HCC include resection, liver transplantation, various percutaneous modalities (such as transarterial chemoembolization [TACE] and thermal ablation), and tyrosine kinase inhibitors (TKIs). Here...

journal_title：Journal of cancer research and therapeutics

authors： Meng M,Li W,Yang X,Huang G,Wei Z,Ni Y,Han X,Wang J,Ye X

更新日期：2020-01-01 00:00:00

abstract：:Retroperitoneal leiomyosarcoma is relatively uncommon. Leiomyosarcoma has accounted for about 5%-10% of soft-tissue sarcoma, and 1/2-2/3 of the primary lesions were retroperitoneal, with a cumulative 5-year survival rate of only 35%.Leiomyosarcoma is one kind of soft-tissue sarcoma with the lowest survival rates due t...

journal_title：Journal of cancer research and therapeutics

authors： Di X,Liang Y,Yu H,Zhao J,Wang Z,Zhao J,Sui A,Zhang H,Wang J

更新日期：2020-01-01 00:00:00

abstract：Objective:The objective of this study is to review the multidetector computed tomography (MDCT) findings of synchronous lymphoma and other solid malignancies. Patients and Methods:This retrospective study included 18 patients confirmed with diagnosis of lymphoma and other solid malignancies. They were 8 women and 10 m...

journal_title：Journal of cancer research and therapeutics

authors： El-Badrawy A,Gadelhak B,Helmy EM,Farouk O,Fady T,Refky B,Elzaafarany M,Emarah Z,Taalab MM,Eisa N,El-Etreby SA,Bahgat MH,El-Badrawy MK,Elalfy H,Besheer T,El-Mesery A,Akl MF,Megahed N,Khashaba EO

更新日期：2020-01-01 00:00:00

abstract：Introduction:The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established. We perform a single institutional retrospective study of CRT in terms of toxicity in elderly patients (age more than 60 years) as compared with young cohort (age <60 years)...

journal_title：Journal of cancer research and therapeutics

authors： Mohata S,Kumar HS,Sharma N,Jhakhar SL,Beniwal S,Harsh KK

更新日期：2020-01-01 00:00:00

abstract：:Lymphoproliferative malignancies can involve both nodal- and extra-nodal tissues. The most common extranodal site involved is the gastrointestinal (GI) tract, and it is secondary to the widespread primary nodal disease. However, about 33% of non-Hodgkin's lymphoma primarily arise from tissues other than lymph nodes, s...

journal_title：Journal of cancer research and therapeutics

authors： Modi V,Bajaj N,Lakkasani S,Shaaban HS,Guron G

更新日期：2020-01-01 00:00:00

abstract：Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

journal_title：Journal of cancer research and therapeutics

authors： Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

更新日期：2019-10-01 00:00:00

abstract：Objective:The objective of this study is to evaluate health literacy level, cervical cancer knowledge, and practice among women patients undergoing screening. Materials and Methods:A cross-sectional study was conducted among 455 women family health center patients. Health literacy level was evaluated by Rapid Estimate...

journal_title：Journal of cancer research and therapeutics

authors： Yilmazel G

更新日期：2019-10-01 00:00:00

abstract：Objective:The aim of good management for cancer survivors should not be limited to only clinical care, but rather it should also include best quality of life (QOL). The objective of this study was to find out various factors affecting QOL in cervical cancer patients so that by modifying these factors, the best QOL can ...

journal_title：Journal of cancer research and therapeutics

authors： Singh U,Verma ML,Rahman Z,Qureshi S,Srivastava K

更新日期：2019-10-01 00:00:00

abstract：:Extraneural broad ligament ependymoma is a rare entity. Herein, we present a case of unusually large broad ligament ependymoma in a 32-year-old female with pain and lump in the lower abdomen. Contrast-enhanced computed tomography abdomen revealed multiple heterogeneously enhancing pelvic masses with lobulated surface ...

journal_title：Journal of cancer research and therapeutics

authors： Kumari A,Diwaker P,Gogoi P,Arora VK,Garg PK,Pandey R

更新日期：2019-10-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.180685]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2019-10-01 00:00:00

abstract：Purpose:We aimed to report the experience of intraoperative electron radiation therapy (IOERT) with Mobetron (Intraop Medical Incorporated, Santa Clara, CA, USA) as a partial breast irradiation (PBI) for patients with early-stage breast cancer and explanation of IOERT application and present early clinical and cosmetic...

journal_title：Journal of cancer research and therapeutics

authors： Avci GG,Güney Y,Küçükpilakci B,Çalikoğlu T,Gülçelik MA,Özaslan C

更新日期：2019-07-01 00:00:00

abstract：Background:Squamous cell carcinoma (SCC) of the breast is an extremely rare tumor with vague natural behavior and treatment. The purpose of this study was to identify the clinicopathological features and treatment results of this rare type of breast cancer. Materials and Methods:The medical files of patients with SCC ...

journal_title：Journal of cancer research and therapeutics

authors： Soliman M

更新日期：2019-07-01 00:00:00

abstract：Aim of Study:One of the new methods that have promising results is the use of cell-derived microvesicles (MVs) to kill tumor cells. Given that MVs contain apoptotic materials, genes, and proteins, they can interfere with the fate of adjacent cells. Materials and Methods:In the present study, after adipose tissue-deriv...

journal_title：Journal of cancer research and therapeutics

authors： Rezaie Z,Ardeshirylajimi A,Ashkezari MD,Seifati SM

更新日期：2019-07-01 00:00:00

abstract：:A 19-year-old girl presented with a lump in her right breast and with a history of surgery for the similar complaint 3 years back. Ultrasound was suggestive of benign solitary lesion of size 16 cm × 10 cm. Core biopsy was suggestive of phyllodes tumor, and the histopathology report of previous surgery was also suggest...

journal_title：Journal of cancer research and therapeutics

authors： Kumar HH,Rahman NKF,Ramesh RS,Raghunandan GC

更新日期：2019-07-01 00:00:00

abstract：Purpose:In low-density (LD) gel dosimeter, diffusive spin-spin relaxation rate (R2)-dispersion caused by susceptibility-induced internal gradient leads to a significant deviation in the measured R2 from the real value. In this study, the effect of induced internal gradient on R2 was visualized and quantified algebraica...

journal_title：Journal of cancer research and therapeutics

authors： Pak F,Vaezzadeh V,Eqlimi E,Mirheydari M

更新日期：2019-07-01 00:00:00