Complete response of a recurrent-metastatic liposarcoma with dedifferentiated histological features following the administration of trabectedin and review of literature.

abstract：:Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...

journal_title：Journal of cancer research and therapeutics

authors： Valecha J,Ojha SS,Sharma A,Nilkanthe R

更新日期：2019-01-01 00:00:00

abstract：Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...

journal_title：Journal of cancer research and therapeutics

authors： Bahadir A,Eral G,Budak M,Shimamoto F,Korpinar MA,Erdamar S,Tuncel H

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:This study was designed to evaluate inter and intraobserver concordance in gross tumor volume (GTV) delineation on megavoltage CT (MVCT) images in patients with postoperative vault recurrences. MATERIALS AND METHODS:Three observers delineated GTV on MVCT and CECT and two observers recontoured on MVCT images. T...

journal_title：Journal of cancer research and therapeutics

authors： Upasani M,Chopra S,Engineer R,Medhi S,Master Z,Mahantshetty U,Shrivastava SK

更新日期：2011-07-01 00:00:00

abstract：:Primary pulmonary epithelioid angiosarcoma is an extremely rare malignancy. Herein, we report the case of an elderly Chinese patient with primary pulmonary epithelioid angiosarcoma. The 72-year-old man presented with a 1-month history of persistent hemoptysis and left chest pain and weight loss of 3 kg. A chest comput...

journal_title：Journal of cancer research and therapeutics

authors： Zhang Y,Huang X,Peng C,Wang Y,Wu Q,Wu Z,Shao H,Wang W

更新日期：2018-06-01 00:00:00

abstract：Context:Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims:In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design:The proposed system includes three m...

journal_title：Journal of cancer research and therapeutics

authors： Zarbakhsh P,Addeh A

更新日期：2018-04-01 00:00:00

abstract：:Neuroblastoma is a tumor of pediatric age group and is extremely rare in adults. Common sites involved in adults are almost similar to that seen in children like retroperitoneum, adrenal gland, pelvis and mediastinum. Ovarian neuroblastoma has never been reported in the literature before. We, hereby, present a case of...

journal_title：Journal of cancer research and therapeutics

authors： Singh M,Arora P,Singh S,Bohara S,Khurana N,Zutshi V,Kumar R

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...

journal_title：Journal of cancer research and therapeutics

authors： Ahmed I,Ferro A,Baby R,Malhotra J,Cohler A,Langenfeld J,Aisner J,Zou W,Jabbour SK

更新日期：2016-04-01 00:00:00

abstract：:Retroperitoneal leiomyosarcoma is relatively uncommon. Leiomyosarcoma has accounted for about 5%-10% of soft-tissue sarcoma, and 1/2-2/3 of the primary lesions were retroperitoneal, with a cumulative 5-year survival rate of only 35%.Leiomyosarcoma is one kind of soft-tissue sarcoma with the lowest survival rates due t...

journal_title：Journal of cancer research and therapeutics

authors： Di X,Liang Y,Yu H,Zhao J,Wang Z,Zhao J,Sui A,Zhang H,Wang J

更新日期：2020-01-01 00:00:00

abstract：Background:Several studies have investigated hypopharyngeal cancer (HC) risk in combination with xenobiotic metabolism-related genetic polymorphisms and the burden of alcohol consumption and smoking in European countries but not in East Asian countries. Patients and Methods:This hospital-based case-control study invol...

journal_title：Journal of cancer research and therapeutics

authors： Yamashita Y,Ikegami T,Suzuki M,Hirakawa H,Maeda H,Yamada S,Deng Z,Kondo S,Kinjyo H,Kiyuna A,Agena S,Uehara T,Ganaha A

更新日期：2019-07-01 00:00:00

abstract：AIM:This study was aimed to assess the in vivo anti-tumoral potency of the novel 6-nitro-2-(3-chloropropyl)-1H-benz[de]isoquinoline-1,3-dione [Compound 1] that has earlier demonstrated excellent cytotoxicity in 15 out of 17 human tumor cell lines tested. MATERIALS AND METHODS:Two murine tumors namely Sarcoma-180 (S-18...

journal_title：Journal of cancer research and therapeutics

authors： Mukherjee A,Dutta S,Sanyal U

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Telomeres, which are bound with shelterin protein complex, play an important role in maintaining genomic stability and its dysfunction may lead to carcinogenesis. Here, we aimed to analyze whether shelterin complex gene expression and telomere length variation, play any role in gallbladder carcinogenesis. M...

journal_title：Journal of cancer research and therapeutics

authors： Poojary SS,Mishra G,Singh TD,Gupta S,Shrivastav BR,Tiwari PK

更新日期：2017-04-01 00:00:00

abstract：:Krukenberg tumor is bilateral ovarian carcinoma's metastasizing most commonly from a gastric primary followed by a colon. We report a case of 36-year-old female with bilateral ovarian mass diagnosed as Krukenberg with a work up for locating the primary site. In this case, we discuss widely the clinical aspects with hi...

journal_title：Journal of cancer research and therapeutics

authors： Umakanthan S,Bukelo MM,Hardik K

更新日期：2015-10-01 00:00:00

abstract：Context:Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) play an indispensable role in the treatment of non-small cell lung cancer (NSCLC), leading to a survival major breakthrough, but there remains no uniform standard for predicting the efficacy of TKI therapy. Aims:We retrospectiv...

journal_title：Journal of cancer research and therapeutics

authors： Yu S,Wang X,Wang X,Wu X,Xu R,Wang X,Zhang X,Zhang C,Chen K,Cheng D,Wenfeng L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Mucin 13 (MUC13) and Mucin 20 (MUC20) are high molecular weight transmembrane O-linked glycoprotein secreted by epithelium and are widely overexpressed in epithelial tumor cells. Previously, it has been reported that MUC13 and MUC20 were prognostic molecular biomarkers of some epithelial tumors, but few has ...

journal_title：Journal of cancer research and therapeutics

authors： Wang H,Shen L,Lin Y,Shi Q,Yang Y,Chen K

更新日期：2015-08-01 00:00:00

abstract：Introduction:Screening and diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and Ultrasonography/ ultrasound (USG) are individually effective diagnostic modalities for detection of breast pathologies...

journal_title：Journal of cancer research and therapeutics

authors： Tiwari P,Ghosh S,Agrawal VK

更新日期：2018-07-01 00:00:00

abstract：Purpose:This study explored ultrasound grayscale ratios (USGRs) for differentiating markedly hypoechoic and anechoic minimal thyroid nodules. Materials and Methods:Longitudinal scan images of 193 markedly hypoechoic papillary thyroid microcarcinoma (PTMC) lesions from 184 patients were retrospectively reviewed using R...

journal_title：Journal of cancer research and therapeutics

authors： Lei ZK,Li MK,Luo DC,Han ZJ

更新日期：2018-01-01 00:00:00

abstract：Background:Nuclear factor kappa B (NFkB-light-chain-enhancer of activated B-cells) expression and its regulation is a key role in the development of number of malignancies, as NFkB mediates the balance between cell death and its survival. Therefore, NFkB regulation constitutes an attractive target to overcome the resis...

journal_title：Journal of cancer research and therapeutics

authors： Iqbal B,Ghildiyal A,Singh S,Siddiqui S,Kumari P,Arshad M,Mahdi AA

更新日期：2018-12-01 00:00:00

abstract：:An important approach for describing a region is to quantify its structure content. In this paper the use of functions for computing texture based on statistical measures is prescribed. MPM (Maximizer of the posterior margins) algorithm is employed. The segmentation based on texture feature would classify the breast t...

journal_title：Journal of cancer research and therapeutics

authors： Sheshadri HS,Kandaswamy A

更新日期：2005-10-01 00:00:00

abstract：:Plasma cell leukemia (PCL) is a rare and an aggressive form of plasma cell dyscrasias. We report a 67-year-old male with PCL which developed while on imatinib mesylate (IM) therapy 38 months after diagnosis of chronic myeloid leukemia (CML). The patient has been treated successfully with bortezomib, melphalan and pred...

journal_title：Journal of cancer research and therapeutics

authors： Maral S,Bakanay SM,Yikilmaz AS,Dilek I

更新日期：2018-10-01 00:00:00

abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...

journal_title：Journal of cancer research and therapeutics

authors： Tsubata Y,Hamada A,Sutani A,Isobe T

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：:Primary mucinous epithelial tumors of the testis are extremely rare. Although isolated case reports and small series have been published, these interesting neoplasms are less well-known. We report a case of a primary intratesticular mucinous cystadenoma in an asymptomatic 44-year-old man. Right radical orchiectomy was...

journal_title：Journal of cancer research and therapeutics

authors： Celdrán JO,Rodríguez CS,Valverde FM,Compiano LO

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine age-specific incidence ratios, gastric cancer localization trend, histologic subtype and cancer related survival that whether have changed during the period from 1999 to 2010. MATERIALS AND METHODS:A total of 866 gastric cancer patients treated at the hospital were retr...

journal_title：Journal of cancer research and therapeutics

authors： Tural D,Selçukbiricik F,Akar E,Serdengeçti S,Büyükünal E

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Changes in salivary flow rate were studied in head and neck (H and N) cancer patients who, after receiving moderately accelerated radiotherapy (RT) and concurrent chemotherapy (CT), were free of disease at 1 year. MATERIALS AND METHODS:Between July 2003 and July 2005, saliva estimation was performed for 36 ...

journal_title：Journal of cancer research and therapeutics

authors： Lal P,Bajpai R,Khurana R,Das KJ,Kumar P,Tiwari A,Gupta N,Kumar S

更新日期：2010-10-01 00:00:00

abstract：Background:Intractable ascites secondary to malignant disease deteriorates patients' quality of life. The purpose of this study was to evaluate the safety and efficacy of percutaneous peritoneovenous (Denver) shunt in treating intractable malignant ascites in cancer patients. Materials and Methods:Thirty-five patients...

journal_title：Journal of cancer research and therapeutics

authors： Tamagawa H,Aoyama T,Inoue H,Fujikawa H,Sawazaki S,Numata M,Sato T,Oshima T,Yukawa N,Morimoto M,Ueno M,Rino Y,Masuda M

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Using physical wedges (PWs) to modify dose distribution and more homogeneous target coverage is a well-established technique. However, there are many problems with PWs known as beam hardening, which made them problematic. This can be overcome by dynamic wedges which do not filter beam. Comparison of physic...

journal_title：Journal of cancer research and therapeutics

authors： Geraily G,Sharafi N,Shirazi A,Esfehani M,Masoudifar M,Rajab BE

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...

journal_title：Journal of cancer research and therapeutics

authors： Dodiya HG,Brahmbhatt AP,Khatri PK,Kaushal AM,Vijay DG

更新日期：2015-07-01 00:00:00

abstract：:Primary mediastinal synovial sarcomas are exceedingly uncommon tumors. Herein, we present the case of primary mediastinal synovial sarcoma (monophasic spindle cell-shaped variant) fully occupying the right hemithorax in a 37-year-old woman who presented to clinic with a 2-month history of right-sided chest pain and sh...

journal_title：Journal of cancer research and therapeutics

authors： Abu-Zaid A,AlNajjar A,Alotaibi S,Alshawaf R,Alqeshtaini N,Alhaidar R,Mohammed S,AlKattan K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The perioperative use of epirubicin, cisplatin, and fluorouracil (ECF) significantly improves outcomes in patients with gastric and gastro-oesophageal (GO) cancers but is cumbersome to administer. Given the equivalence of epirubicin, oxaliplatin, and capectabine (EOX) with ECF in advanced setting, we analyze...

journal_title：Journal of cancer research and therapeutics

authors： Sirohi B,Barreto SG,Singh A,Batra S,Mittra A,Rastogia S,Ramadwar M,Shetty N,Goel M,Shrikhande SV

更新日期：2014-10-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, soft tissue tumor. Its occurrence over face is very rare. We are presenting a case of giant DFSP over left cheek, which produces oncological, functional and esthetic challenges and deals by multidisciplinary team. We also reviewed the relevant ...

journal_title：Journal of cancer research and therapeutics

authors： Kumar L,Bhandari V,Singh S,Garg P,Kumar A

更新日期：2015-10-01 00:00:00