Acute treatment-related toxicity in elderly patients with good performance status compared to young patients in locally advanced esophageal carcinoma treated by definitive chemoradiation: A retrospective comparative study.

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：Objective:This study presents a method to estimate midplane dose (Diso, transit) in vivo from transit signal (St) measured with thimble ionization chamber in cancer of the middle-third esophagus patients treated with three-dimensional radiotherapy (RT). This detector is positioned at the level of electronic portal imag...

journal_title：Journal of cancer research and therapeutics

authors： Kumar PS,Banerjee S,Arun Kumar ES,Srinivas C,Vadhiraja BM,Saxena PU,Ravichandran R,Kasturi DP

更新日期：2018-01-01 00:00:00

abstract：AIM:The discipline of radiotherapy (RT) in India is considered a low priority subject. Postgraduate (PG) students rarely choose RT as a career option. The possible reasons could be: 1) limited availability of PG course training centers, 2) limited job prospects, etc. We decided to conduct a survey of undergraduate (UG)...

journal_title：Journal of cancer research and therapeutics

authors： Sharma DN,Rath GK,Parashar A,Singh P

更新日期：2010-01-01 00:00:00

abstract：Background:Colorectal cancer (CRC) is the second most diagnosed cancer often identified during the later stages of carcinogenesis. Orientin, a C-glycoside of luteolin, is well known for its versatile therapeutic action toward oxidative stress-induced cellular response may exert chemoprevention against CRC. Materials a...

journal_title：Journal of cancer research and therapeutics

authors： Thangaraj K,Natesan K,Settu K,Palani M,Govindarasu M,Subborayan V,Vaiyapuri M

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Treatment of proliferative diseases of the hematopoietic system involves, in most cases, chemotherapy combined with radiation therapy, which is intended to provide adequate immunosuppressant. Conventionally, total body irradiation (TBI) was used; however, total marrow irradiation (TMI) performed with helic...

journal_title：Journal of cancer research and therapeutics

authors： Konstanty E,Malicki J,Łagodowska K,Kowalik A

更新日期：2017-01-01 00:00:00

abstract：Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated ...

journal_title：Journal of cancer research and therapeutics

authors： Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari F

更新日期：2019-03-01 00:00:00

abstract：Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

journal_title：Journal of cancer research and therapeutics

authors： Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Changes in salivary flow rate were studied in head and neck (H and N) cancer patients who, after receiving moderately accelerated radiotherapy (RT) and concurrent chemotherapy (CT), were free of disease at 1 year. MATERIALS AND METHODS:Between July 2003 and July 2005, saliva estimation was performed for 36 ...

journal_title：Journal of cancer research and therapeutics

authors： Lal P,Bajpai R,Khurana R,Das KJ,Kumar P,Tiwari A,Gupta N,Kumar S

更新日期：2010-10-01 00:00:00

abstract：Context:The metastasis of liver cancer is a major cause of clinical treatment failure, restrain, and control the cancer metastasis is the major strategy of the treatment and prevention of the disease. Special AT-rich sequence-binding protein 1 (SATB1) gene was overexpressed in many malignant tumors and considered as a ...

journal_title：Journal of cancer research and therapeutics

authors： Xu C,Guo H,Kong D,Pang D,Ding Y

更新日期：2018-12-01 00:00:00

abstract：Background and Objectives:Quid-chewing habit is a common and old tradition in India. It causes various potentially malignant disorders. Therefore, a study was undertaken to analyze the association of various quid-chewing habit patterns and different oromucosal lesions. Materials and Methods:A cross-sectional study was...

journal_title：Journal of cancer research and therapeutics

authors： Avinash Tejasvi ML,Anulekha CK,Afroze MM,Shenai KP,Chatra L,Bhayya H

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:The oncogenic form of anaplastic lymphoma kinase (ALK) gene is an attractive candidate marker for diagnostic and therapeutic purposes in several malignancies, including nonsmall cell lung cancer (NSCLC). This study aimed to examine the expression levels and clinical significance of ALK in a series of NSCLC...

journal_title：Journal of cancer research and therapeutics

authors： Roudi R,Haji G,Madjd Z,Shariftabrizi A,Mehrazma M

更新日期：2016-04-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.180080.]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2016-04-01 00:00:00

abstract：Purpose:This study explored ultrasound grayscale ratios (USGRs) for differentiating markedly hypoechoic and anechoic minimal thyroid nodules. Materials and Methods:Longitudinal scan images of 193 markedly hypoechoic papillary thyroid microcarcinoma (PTMC) lesions from 184 patients were retrospectively reviewed using R...

journal_title：Journal of cancer research and therapeutics

authors： Lei ZK,Li MK,Luo DC,Han ZJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The perioperative use of epirubicin, cisplatin, and fluorouracil (ECF) significantly improves outcomes in patients with gastric and gastro-oesophageal (GO) cancers but is cumbersome to administer. Given the equivalence of epirubicin, oxaliplatin, and capectabine (EOX) with ECF in advanced setting, we analyze...

journal_title：Journal of cancer research and therapeutics

authors： Sirohi B,Barreto SG,Singh A,Batra S,Mittra A,Rastogia S,Ramadwar M,Shetty N,Goel M,Shrikhande SV

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess Ezrin expression in the primary hepatic carcinoma patients and associated with clinical, pathological characteristics. MATERIALS AND METHODS:Fifty-one patients with primary hepatocellular carcinoma (PHC) with completed clinical data were retrospectively analyzed in this st...

journal_title：Journal of cancer research and therapeutics

authors： Pan D,Wang S,Ye H,Xu S,Ye G

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Isolated primary pancreatic lymphoma (PPL) is a rare extra-lymphatic non-Hodgkin's lymphoma comprising less than 1% of all extra-lymphatic lymphomas. It is seen in people of advanced age and there is a slight male preponderance. It is difficult to diagnose; the vague presenting symptoms and nonspecific labor...

journal_title：Journal of cancer research and therapeutics

authors： Basu A,Patil N,Mohindra P,Zade B,Gujral S,Muckaden MA,Laskar S

更新日期：2007-10-01 00:00:00

abstract：CONTEXT:Free radical associated damages play a major role in causation of cancer in tobacco habituates. The free radicals released by tobacco bring about alterations in antioxidant levels in humans and these free radical associated damages are reflected through antioxidant enzyme activities in blood. AIMS:To evaluate ...

journal_title：Journal of cancer research and therapeutics

authors： Naga Sirisha CV,Manohar RM

更新日期：2013-04-01 00:00:00

abstract：:In recent years, using the ionizing radiation in the interventional cardiology has been increased; this is because of the rapid growth of the number of interventional procedures and the high levels of radiation dose in these examinations. Therefore, it is necessary to develop procedures for managing the use of fluoros...

journal_title：Journal of cancer research and therapeutics

authors： Fardid R,Mirzadeh F,Rezaei H

更新日期：2017-10-01 00:00:00

abstract：AIM:To evaluate the integral dose to carotid vessels in extended field intensity modulated radiotherapy (IMRT) (including the lower neck nodes in IMRT field) and split field IMRT (using separate single anterior field to treat lower neck nodes) in cancer nasopharynx. MATERIALS AND METHODS:Dosimetric data from 10 patien...

journal_title：Journal of cancer research and therapeutics

authors： Bahl A,Basu KS,Sharma DN,Rath GK,Julka PK,Thulkar S

更新日期：2010-10-01 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a group of sarcomas that exhibit a myomelanocytic phenotype and possess a unique cell type in the perivascular epithelioid cell. Traditionally HMB-45 immunoreactivity is the first criteria required to consider a tumor to be PEComa. We report a case of multifocal PEComa w...

journal_title：Journal of cancer research and therapeutics

authors： Kapoor A,Beniwal S,Singhal MK,Kumar N,Kumar V,Kumar HS

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Oral cancer is the third most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Transformation of normal tissue to premalignant lesion and further to oral cancer results in alteration in glycolytic pathway and hence the lactate dehydrogenase levels. Therefore...

journal_title：Journal of cancer research and therapeutics

authors： Shetty SR,Chadha R,Babu S,Kumari S,Bhat S,Achalli S

更新日期：2012-01-01 00:00:00

abstract：Background:Lung cancer is the leading cause of cancer-related deaths worldwide. The high resistance of this type of cancer to radiotherapy and chemotherapy is the greatest challenge for the complete eradication of cancer cells. Although the combination of chemotherapeutic agents has some promising results, severe side ...

journal_title：Journal of cancer research and therapeutics

authors： Kahkesh MH,Salehi Z,Najafi M,Ghobadi A,Izad M,Shirazi A

更新日期：2020-10-01 00:00:00

abstract：:Intra-nodal palisaded myofibroblastoma (IPM) is a rare benign lymph node mesenchymal tumor. It presents as a slow growing, painless nodular mass confined mostly to the inguinal area. Histologically, it shows palisading spindle cells, hemorrhages, hemosiderin laden macrophages, and amianthoid fibers, almost totally rep...

journal_title：Journal of cancer research and therapeutics

authors： Sarma NH,Arora KS,Varalaxmi KP

更新日期：2013-04-01 00:00:00

abstract：CONTEXT:The diagnosis of malignant and potentially malignant epithelial lesions of oral mucosa cannot be based solely on clinical findings. The histologic evaluation of a representative biopsy specimen thus becomes necessary. The site for biopsy, however, is always a subjective choice that sometimes raises doubts about...

journal_title：Journal of cancer research and therapeutics

authors： Nayyar AS,Khan M,Bafna UD,Ahmed S,Chaluvaiah GH

更新日期：2014-07-01 00:00:00

abstract：:Neuroblastoma is a tumor of pediatric age group and is extremely rare in adults. Common sites involved in adults are almost similar to that seen in children like retroperitoneum, adrenal gland, pelvis and mediastinum. Ovarian neuroblastoma has never been reported in the literature before. We, hereby, present a case of...

journal_title：Journal of cancer research and therapeutics

authors： Singh M,Arora P,Singh S,Bohara S,Khurana N,Zutshi V,Kumar R

更新日期：2010-07-01 00:00:00

abstract：:Papillary carcinoma is a well-differentiated type of thyroid carcinoma with very good overall prognosis. The commonest site of metastases is the lymph node, distant metastases being rare. We present a case of a 52-year-old male who presented with a solitary metastasis in the left para-sellar region and cavernous sinus...

journal_title：Journal of cancer research and therapeutics

authors： Chandarana MN,Epari S,Chaukar D,Moiyadi AV

更新日期：2012-07-01 00:00:00

abstract：:Prostate cancer, one of the most common male malignancies with an increasing incidence in the recent years, requires the development of new methods of treatment. One of the most debated subjects is the tumor-associated macrophages (TAM). Although, the pathophysiological mechanisms are still a subject of intense resear...

journal_title：Journal of cancer research and therapeutics

authors： Nenu I,Gafencu GA,Popescu T,Kacso G

更新日期：2017-07-01 00:00:00

abstract：:Chondroblastoma is a rare, benign tumor derived from chondroblasts, commonly presenting in the second decade of life. It is usually found in the epiphysis or apophysis of long bones; however, it may rarely affect flat bones like scapula. Occasionally a histologically typical chondroblastoma may exhibit an aggressive b...

journal_title：Journal of cancer research and therapeutics

authors： Dhanda S,Menon S,Gulia A

更新日期：2015-07-01 00:00:00

abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...

journal_title：Journal of cancer research and therapeutics

authors： Tsubata Y,Hamada A,Sutani A,Isobe T

更新日期：2012-01-01 00:00:00

abstract：:The novel coronavirus (COVID-19) pandemic has disrupted healthcare delivery across the globe. Cancer patients are at a higher risk of acquiring this infection due to their immunosuppressed state. Timely care of patients while ensuring safety of healthcare workers is need of the hour. We list few precautionary measures...

journal_title：Journal of cancer research and therapeutics

authors： Mummudi N,Tibdewal A,Ghosh-Laskar S,Agarwal JP

更新日期：2020-04-01 00:00:00