Abstract:
Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated in the presence of wedge and block in 15 MV photon fields of Siemens Primus linear accelerator. Materials and Methods:Neutron production by 30°, 45°, and 60° wedges and cerrobend block was investigated. Measurements were conducted in a 10 cm × 10 cm field at the source to -surface distance of 100 cm at 0.5, 2, 3, and 4 cm depths of a 30 cm × 30 cm × 30 cm Perspex phantom using the CR-39 passive film detectors. Chemical etching was performed using sodium hydroxide solution with 6.25 M concentration as the etchant at 85°C for 3 h. Results:The neutron dosimetry results reveal that the presence of wedge and block increases the neutron contamination. However, the 45° wedge is most effective in producing neutron contamination. The results also show that the fast neutron contamination is lower in the steeper depths. Conclusion:The presence of a wedge in a therapeutic high-energy photon field is a source of neutron contamination and may be of concern regarding clinical aspects. The results of this study show that superficial tissues such as skin will incur higher fast neutron contamination than the deep tissues.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari Fdoi
10.4103/jcrt.JCRT_1257_16subject
Has Abstractpub_date
2019-03-01 00:00:00pages
S103-S109issue
Supplementeissn
0973-1482issn
1998-4138pii
JCanResTher_2019_15_8_103_243478journal_volume
15pub_type
杂志文章abstract:Aims:To find the spectrum and frequency of lower gastrointestinal malignancies and diagnostic accuracy of colonoscopic brush cytology in their diagnosis. Materials and Methods:This was a prospective study carried out on 49 patients in the Department of Pathology over 1 year. Brushing material was smeared directly onto...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.176416
更新日期:2018-04-01 00:00:00
abstract:Introduction:Screening and diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and Ultrasonography/ ultrasound (USG) are individually effective diagnostic modalities for detection of breast pathologies...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.191053
更新日期:2018-07-01 00:00:00
abstract:Aim of Study:Metabolic syndrome (MetS) is an abnormality that increases the risk of cardiovascular disease and diabetes. In the recent years, studies showed that MetS is associated with increased risk of incidence, aggressiveness, and mortality of prostate cancer (PCa). We examined the influence of MetS at final pathol...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.187290
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.146056
更新日期:2015-07-01 00:00:00
abstract:Background:Apatinib has been approved for the treatment of advanced gastric adenocarcinoma and gastric-esophageal junctional adenocarcinoma, but its efficacy is unknown for other advanced solid tumors. Aims and Objectives:We retrospectively reviewed the use of apatinib for multiple advanced-stage non-gastric cancers. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_24_19
更新日期:2019-01-01 00:00:00
abstract:Introduction:Oral squamous cell carcinoma (OSCC) accounts 94% of all malignant lesions in the oral cavity. In the assessment of OSCC, nowadays the WHO grading system has been followed widely but due to its subjectivity, investigators applied the sophisticated technique of computer-assisted image analysis in the grading...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.189423
更新日期:2018-01-01 00:00:00
abstract:Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_1277_16
更新日期:2019-01-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/0973-1482.188431]. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 已发布勘误
doi:10.4103/0973-1482.303909
更新日期:2020-10-01 00:00:00
abstract:CONTEXT:The critical condition of the cancer patient and the stringent medical procedures do not often warrant the accessibility of the patient for psychological evaluation. Therefore, the study is conceptualized to assess the psychological problems of caregivers, which in turn have their impact upon cancer patients. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.146088
更新日期:2016-01-01 00:00:00
abstract::Lymphoma of the salivary gland accounts for 5% of cases of extranodal lymphoma and 10% of malignant salivary gland tumors. Most primary salivary gland lymphomas are B marginal zone lymphomas arising on a background of sialadenitis associated with an autoimmune disorder such as Sjorgen's syndrome. This report describes...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.106586
更新日期:2012-10-01 00:00:00
abstract::Large pedunculated esophageal lipoma is uncommon. The presenting symptoms of esophageal lipoma are dysphagia, regurgitated mass, and persistent sensation of a lump in the throat. The most frequent location of the tumor pedicle is the upper esophageal sphincter. Here, we present the case of a 52-year-old man who had th...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
doi:10.4103/0973-1482.154089
更新日期:2015-10-01 00:00:00
abstract:Purpose:To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort. Patients and Methods:Eighty-four eyes of 62 consecutive patients with advanced refractory RB who received IAC were included in the study dur...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_722_17
更新日期:2018-01-01 00:00:00
abstract:Context/Background:Tooth agenesis (excluding third molars) is a common congenital disorder that affects 2.2-10% of the general population. A number of different genes have been shown to be associated with cases of tooth agenesis including AXIN2, IRF6, FGFR1, MSX1, PAX9, and TGFA. Wingless/integration signaling gene, AX...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.168997
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Changes in salivary flow rate were studied in head and neck (H and N) cancer patients who, after receiving moderately accelerated radiotherapy (RT) and concurrent chemotherapy (CT), were free of disease at 1 year. MATERIALS AND METHODS:Between July 2003 and July 2005, saliva estimation was performed for 36 ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.77105
更新日期:2010-10-01 00:00:00
abstract::The mixed lineage leukemia (MLL) gene at chromosome band 11q23 is commonly involved in reciprocal translocations that is detected in acute leukemia. The MLL gene, commonly known as mixed lineage leukemia or myeloid lymphoid leukemia, has been independently identified and cloned from the 11q23 breakpoint of acute leuke...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.119309
更新日期:2013-07-01 00:00:00
abstract::Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.193111
更新日期:2018-01-01 00:00:00
abstract:AIM:To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). MATERIALS AND METHODS:We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. RESULTS:Age at presentation varied from...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.136570
更新日期:2014-04-01 00:00:00
abstract:Aim of Study:The roles of autophagy performed in chemotherapy-induced cell death or proliferation inhibition were still in debate. In this study, we aimed to disclose the function of autophagy in chemotherapy of HCT-116 colon cells. Materials and Methods:Pharmacological and genetic methods were applied to induce and i...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.204898
更新日期:2018-12-01 00:00:00
abstract:AIM:To determine the efficacy of belly board device in patients receiving postoperative radiation for gynecological malignancies in terms of setup error and acute small bowel toxicity. MATERIALS AND METHODS:Patients requiring postoperative radiation for gynecological malignancies were prospectively randomized to eithe...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.179519
更新日期:2017-07-01 00:00:00
abstract:AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.163682
更新日期:2016-01-01 00:00:00
abstract::A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/jcrt.JCRT_1194_16
更新日期:2019-07-01 00:00:00
abstract:Aims:The role of prophylactic central neck dissection (CND) in the management of papillary thyroid carcinoma (PTC) is controversial. This study reports outcomes of an observational approach in PTC patients without clinical evidence of lymph node metastasis. Materials and Methods:Patients with PTC who had surgery (with...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_620_19
更新日期:2020-09-01 00:00:00
abstract::Dermatofibrosarcoma protuberans (DFSP) is a low-grade tumor with rare metastasis. A 26-year-old male presented with multiple cutaneous nodular lesions of DFSP since 3 months along with distant metastasis to the brain, pleura, and muscles that were detected on investigations. The case is being reported due to its rare ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.146099
更新日期:2015-07-01 00:00:00
abstract::Skin metastases, as a presenting symptom of gastrointestinal malignancies, are very rare and signify aggressive disease. They usually occur after a long period of diagnosis and along with other visceral metastases. We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.172586
更新日期:2018-04-01 00:00:00
abstract:Aims:This study is carried out to report on the knowledge and practice regarding breast self-examination (BSE) among women from the city of Mosul in Iraq and to evaluate the prevalence of performing clinical breast examination (CBE) and mammography among them. Settings and Design:A descriptive, cross-sectional survey ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_736_19
更新日期:2020-10-01 00:00:00
abstract::An important approach for describing a region is to quantify its structure content. In this paper the use of functions for computing texture based on statistical measures is prescribed. MPM (Maximizer of the posterior margins) algorithm is employed. The segmentation based on texture feature would classify the breast t...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.19599
更新日期:2005-10-01 00:00:00
abstract:AIM OF STUDY:To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver nanoparticles (SNs) to tumor growth in a murine model. MATERIALS AND METHODS:Sanazole (AK) and DOX were complexed with SNs, individually and in combination to obtain SN-AK, SN-DOX, and SN-AK-DOX....
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.148705
更新日期:2014-10-01 00:00:00
abstract::Primary amyloidosis of bladder is a rare disease that closely resembles bladder cancer on clinical presentation with painless gross hematuria. Pathologically this is a totally benign non-neoplastic lesion and its association with urothelial carcinoma of the bladder is rare. We herein report a 64-year-old diabetic male...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.98994
更新日期:2012-04-01 00:00:00
abstract:AIM OF STUDY:Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. Recently, genome-wide association studies have identified two single nucleotide polymorphisms (SNP) associated with CRC in Caucasians. MATERIALS AND METHODS:To validate whether the same variation...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.150346
更新日期:2015-04-01 00:00:00
abstract::Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.73328
更新日期:2010-07-01 00:00:00