Salivary lactate dehydrogenase levels in oral leukoplakia and oral squamous cell carcinoma: a biochemical and clinicopathological study.

abstract：BACKGROUND:The integrity of the immune system is necessary to control tumor progression and a compromised state contributes to tumor escape. AIMS:The study intends to evaluate the presence and distribution pattern of Langerhans cells (LC) in Oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC) oral ...

journal_title：Journal of cancer research and therapeutics

authors： Upadhyay J,Rao NN,Upadhyay RB

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To report our experience of stereotactic radiosurgery (SRS) in consecutively treated patients with arteriovenous malformations (AVMs). MATERIALS AND METHODS:Of the 87 patients, 23 patients qualified and were treated with SRS as per predefined protocol according to AVM size, location, neurological status, prior...

journal_title：Journal of cancer research and therapeutics

authors： Jalali R,Dutta D,Srinivas C,Munshi A,Limaye U,Goel A,Deshpande D,Sarin R

更新日期：2009-07-01 00:00:00

abstract：Background:Interleukin (IL)-17A and IL-17F are inflammatory cytokines mainly produced by T helper 17 cells. IL-17A is known to be protumorigenic while IL-17F has a protective role in cancer. A number of studies have been conducted to determine the association between polymorphisms of IL-17AG197A (rs2275913) and IL-17FA...

journal_title：Journal of cancer research and therapeutics

authors： Samiei G,Yip WK,Leong PP,Jabar MF,Dusa NM,Mohtarrudin N,Seow HF

更新日期：2018-06-01 00:00:00

abstract：:The relationship of hypercalcemia with cancer is well described in the literature. Breast cancer is the commonest malignancy associated with hypercalcemia; the detection of hypercalcemia in these patients usually signifies metastatic disease and is associated with a poor prognosis. However, the treating oncologist sho...

journal_title：Journal of cancer research and therapeutics

authors： Rao V,Chaukar D,D'Cruz AK

更新日期：2009-01-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the effect of adding etoposide and ifosfamide chemotherapy drugs to treatment regimen of patients affected with osteosarcoma and to determine the clinical process and response to treatment during a follow-up period of 11 years. MATERIALS AND METHODS:Forty patients with osteosa...

journal_title：Journal of cancer research and therapeutics

authors： Aznab M,Hematti M

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Tobacco use has been associated with various carcinomas including lung, esophagus, larynx, mouth, throat, kidney, bladder, pancreas, stomach, and cervix. Biomarkers such as concentration of cotinine in the blood, urine, or saliva have been used as objective measures to distinguish nonusers and users of tobac...

journal_title：Journal of cancer research and therapeutics

authors： Balhara YP,Jain R

更新日期：2013-01-01 00:00:00

abstract：Objective:This study presents a method to estimate midplane dose (Diso, transit) in vivo from transit signal (St) measured with thimble ionization chamber in cancer of the middle-third esophagus patients treated with three-dimensional radiotherapy (RT). This detector is positioned at the level of electronic portal imag...

journal_title：Journal of cancer research and therapeutics

authors： Kumar PS,Banerjee S,Arun Kumar ES,Srinivas C,Vadhiraja BM,Saxena PU,Ravichandran R,Kasturi DP

更新日期：2018-01-01 00:00:00

abstract：:A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...

journal_title：Journal of cancer research and therapeutics

authors： Sayit AT,Elmali M,Gul A,Sullu Y

更新日期：2019-07-01 00:00:00

abstract：Purpose:In low-density (LD) gel dosimeter, diffusive spin-spin relaxation rate (R2)-dispersion caused by susceptibility-induced internal gradient leads to a significant deviation in the measured R2 from the real value. In this study, the effect of induced internal gradient on R2 was visualized and quantified algebraica...

journal_title：Journal of cancer research and therapeutics

authors： Pak F,Vaezzadeh V,Eqlimi E,Mirheydari M

更新日期：2019-07-01 00:00:00

abstract：Background:We assessed the frequency of epigenetic lesions, including lymphoid-specific helicase (LSH), 5-hydroxymethylcytosine (5-hmC) and E2F1, and the possible correlations among molecular findings, phenotype, clinical features, and outcome. Methods:We investigated 181 paraffin-embedded B-cell lymphoma samples usin...

journal_title：Journal of cancer research and therapeutics

authors： Ouyang C,Deng Z,Zhou J,Fu C,Liu S,Tao Y,Xiao D

更新日期：2019-01-01 00:00:00

abstract：Objective:To discuss and assess the clinical value of treating lung cancer cachexia with thalidomide combined with cinobufagin.s. Methods:A cohort of 54 patients, who were diagnosed with lung carcinoma, was randomly divided into two groups, a trial group and a control group, respectively. The trial group was given 150...

journal_title：Journal of cancer research and therapeutics

authors： Xie M,Chen X,Qin S,Bao Y,Bu K,Lu Y

更新日期：2018-01-01 00:00:00

abstract：AIMS:To analyze the differences in dose distribution, with ovoid separation in various applications, by different radiotherapists in the same patient of carcinoma of the uterine cervix treated by multiple fractions of high-dose-rate (HDR) intracavitary Radio therapy (ICRT). SETTINGS:Pravara Rural Hospital and Rural Me...

journal_title：Journal of cancer research and therapeutics

authors： Jain VS,Singh KK,Umberkar RB,Sarje MB,Jain SM

更新日期：2010-04-01 00:00:00

abstract：Objective:The aim of this study is to probe in the inhibitory effects of ginsenoside Rg3 on the expression of hypoxia-induced factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in human gastric cancer cells. Materials and Methods:Human gastric cancer BGC823 cells were divided into the control group and e...

journal_title：Journal of cancer research and therapeutics

authors： Li B,Qu G

更新日期：2019-01-01 00:00:00

abstract：:Malignant brain tumors are a significant health problem in children and adults and are largely unmanageable. As a metabolic disorder involving the dysregulation of glycolysis and respiration (the Warburg effect), malignant brain cancer can be managed through changes in metabolic environment. In contrast to malignant b...

journal_title：Journal of cancer research and therapeutics

authors： Seyfried BT,Kiebish M,Marsh J,Mukherjee P

更新日期：2009-09-01 00:00:00

abstract：:Placement of long term central venous access devices (CVAD) such as chemo ports and Hickman's catheters are associated with a definite risk of catheter tip malpositioning. As such, malpositioning runs a risk of venous thrombosis and related complications; it is imperative to reposition the catheter. Percutaneous trans...

journal_title：Journal of cancer research and therapeutics

authors： Chauhan A,Pathak K,Ganguly M

更新日期：2010-01-01 00:00:00

abstract：:Many oral lesions may need to be diagnosed by removing a sample of tissue from the oral cavity. Biopsy is widely used in the medical field, but the practice is not quite widespread in dental practice. As oral pathologists, we have found many artifacts in the tissue specimen because of poor biopsy technique or handling...

journal_title：Journal of cancer research and therapeutics

authors： Kumaraswamy KL,Vidhya M,Rao PK,Mukunda A

更新日期：2012-04-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：Objective:This study aimed to explore the risk factors of hepatocellular carcinoma (HCC) and survival analysis for cirrhosis after transjugular intrahepatic portosystemic shunt (TIPS) in treating portal hypertension. Materials and Methods:A retrospective database review was performed, including 106 patients (33 female...

journal_title：Journal of cancer research and therapeutics

authors： Wei J,Li H,Li C

更新日期：2018-01-01 00:00:00

abstract：Background:Lung cancer is the leading cause of cancer-related deaths worldwide. The high resistance of this type of cancer to radiotherapy and chemotherapy is the greatest challenge for the complete eradication of cancer cells. Although the combination of chemotherapeutic agents has some promising results, severe side ...

journal_title：Journal of cancer research and therapeutics

authors： Kahkesh MH,Salehi Z,Najafi M,Ghobadi A,Izad M,Shirazi A

更新日期：2020-10-01 00:00:00

abstract：Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated ...

journal_title：Journal of cancer research and therapeutics

authors： Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari F

更新日期：2019-03-01 00:00:00

abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare condition of ectopic calcification leading to increasing disability throughout life, with most patients being wheelchair bound by the age of 30. Ectopic calcification can be triggered by trauma and it is therefore important to minimize biopsies and operative proced...

journal_title：Journal of cancer research and therapeutics

authors： Frew JA,Kelly CG

更新日期：2008-01-01 00:00:00

abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...

journal_title：Journal of cancer research and therapeutics

authors： Tsubata Y,Hamada A,Sutani A,Isobe T

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1), which has been isolated from dried Antrodi...

journal_title：Journal of cancer research and therapeutics

authors： Wei PL,Tu SH,Lien HM,Chen LC,Chen CS,Wu CH,Huang CS,Chang HW,Chang CH,Tseng H,Ho YS

更新日期：2012-10-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, soft tissue tumor. Its occurrence over face is very rare. We are presenting a case of giant DFSP over left cheek, which produces oncological, functional and esthetic challenges and deals by multidisciplinary team. We also reviewed the relevant ...

journal_title：Journal of cancer research and therapeutics

authors： Kumar L,Bhandari V,Singh S,Garg P,Kumar A

更新日期：2015-10-01 00:00:00

abstract：AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...

journal_title：Journal of cancer research and therapeutics

authors： Yilmaz U,Yılmaz U,Yasar Z,Kıraklı EK,Ulger S,Ozdogan Y,Demirci NY,Erol S,Ozdogan I,Sahin B,Koksal D,Akcay C

更新日期：2016-01-01 00:00:00

abstract：:Camrelizumab is a programmed death receptor-1 inhibitor originally developed in China for the treatment of refractory lymphoma. It has also been effective in non-small-cell lung cancer patients. However, the rechallenge of camrelizumab was not reported previously. We report the rechallenge of camrelizumab therapy in t...

journal_title：Journal of cancer research and therapeutics

authors： Wei Z,Yang X,Ye X

更新日期：2020-09-01 00:00:00

abstract：CONTEXT:Cervical cancer is a preventable disease; it is the primary cancer amongst women in South Africa. AIMS:The objective of this study is to assess the awareness and detection methods of cervical cancer. SETTINGS AND DESIGN:This was a cross-sectional study conducted among 180 full time final year undergraduate fe...

journal_title：Journal of cancer research and therapeutics

authors： Hoque ME

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Telomeres, which are bound with shelterin protein complex, play an important role in maintaining genomic stability and its dysfunction may lead to carcinogenesis. Here, we aimed to analyze whether shelterin complex gene expression and telomere length variation, play any role in gallbladder carcinogenesis. M...

journal_title：Journal of cancer research and therapeutics

authors： Poojary SS,Mishra G,Singh TD,Gupta S,Shrivastav BR,Tiwari PK

更新日期：2017-04-01 00:00:00

abstract：:Renal cell carcinoma, unclassified constitute about 3-4% of all renal carcinomas. It essentially is a tumor where more than morphological variants or subtypes are seen in a single tumor. Usually there is a mixture of 2-3 different types. However, in this particular case there were at least 5 different types of morphol...

journal_title：Journal of cancer research and therapeutics

authors： Chander B,Preet K,Bharti R,Deb P

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Management of recurrent presacral rectal cancer is often not amenable to curative surgery. The goal of this study is to evaluate the safety and efficacy of cyberknife stereotactic body radiotherapy (SBRT) in the management of presacral recurrences. MATERIALS AND METHODS:Between April 2003 and October 2008, 14 ...

journal_title：Journal of cancer research and therapeutics

authors： Defoe SG,Bernard ME,Rwigema JC,Heron DE,Ozhasoglu C,Burton S

更新日期：2011-10-01 00:00:00