Telomere length variation and expression analysis of shelterin complex genes during gallbladder carcinogenesis.

abstract：OBJECTIVE:This study aimed to compare the dose difference in 125 I seed implantation between three-dimensional (3D) print template-guided operation and traditional implantation. MATERIALS AND METHODS:This study retrospectively analyzed 27 patients who underwent 125I seed implantation from August 2015 to December 2015 ...

journal_title：Journal of cancer research and therapeutics

authors： Hongtao Z,Xuemin D,Huimin Y,Zeyang W,Lijuan Z,Jinxin Z,Zezhou L,Aixia S,Juan W

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Intracranial meningiomas are the second most common tumor of the CNS. The high-grade tumors are atypical and malignant meningioma comprising 5-7% and 1-3% of all meningiomas. The high-grade meningioma have an aggressive histopathological and clinical behavior. MATERIALS AND METHODS:We retrospectively revi...

journal_title：Journal of cancer research and therapeutics

authors： Kumar N,Kumar R,Khosla D,Salunke PS,Gupta SK,Radotra BD

更新日期：2015-10-01 00:00:00

abstract：Background:Conventional magnetic resonance imaging (MRI) does not accurately evaluate lymph node (LN) status, which is essential for the treatment and prognosis assessment in patients with rectal cancer. Objective:The aim of this study is to evaluate the diagnostic value of intravoxel incoherent motion (IVIM) MRI in d...

journal_title：Journal of cancer research and therapeutics

authors： Long L,Zhang H,He X,Zhou J,Guo D,Liu X

更新日期：2019-01-01 00:00:00

abstract：:Gardasil is the first quadrivalent human papillomavirus (HPV)-types 6, 11, 16, 18 recombinant vaccine approved by the FDA on June 8, 2006. It induces genotype-specific virus-neutralizing antibodies and prevents infection with HPV. Various clinical trials demonstrated a reduction in the incidence of vaccine-type-specif...

journal_title：Journal of cancer research and therapeutics

authors： Sharma R,Sharma CL

更新日期：2007-04-01 00:00:00

abstract：Background:The aim of this study is to determine the prognostic factors which affect both disease-free survival (DFS) and overall survival (OS) in thyroid papillary carcinoma with clinical lateral lymph node metastasis. Methods:One hundred and three papillary thyroid carcinomas diagnosed in adult patients received the...

journal_title：Journal of cancer research and therapeutics

authors： Yuksel UM,Turanli S,Acar Y,Berberoglu U

更新日期：2019-07-01 00:00:00

abstract：:Tumors arising from Meckel's diverticulum (MD) reported in the literature are mainly carcinoid and gastrointestinal stromal tumors. We herein report a rare case of adenocarcinoma arising from intestinal mucosa in an MD with multiple liver metastases at the onset of symptoms. A 57-year-old female complaining of bloody ...

journal_title：Journal of cancer research and therapeutics

authors： Zhao Y,Yang X,Ye Y

更新日期：2017-01-01 00:00:00

abstract：Aims:The role of prophylactic central neck dissection (CND) in the management of papillary thyroid carcinoma (PTC) is controversial. This study reports outcomes of an observational approach in PTC patients without clinical evidence of lymph node metastasis. Materials and Methods:Patients with PTC who had surgery (with...

journal_title：Journal of cancer research and therapeutics

authors： Huang H,Wu L,Liu W,Liu J,Liu Y,Xu Z

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：:Skin metastases, as a presenting symptom of gastrointestinal malignancies, are very rare and signify aggressive disease. They usually occur after a long period of diagnosis and along with other visceral metastases. We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature ...

journal_title：Journal of cancer research and therapeutics

authors： Nallathambi C,Singh IY,Patton Z

更新日期：2018-04-01 00:00:00

abstract：:Masseter hypertrophy is a characteristic condition resulting from an increase in the size of the muscle mass. At times, it produces significant facial asymmetry and is an important finding in the differential diagnosis of similar located entities. A proper diagnosis of this condition would avoid more aggressive and un...

journal_title：Journal of cancer research and therapeutics

authors： Naphade VV,Kedia SG,Patil P,Khare S

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma is the most common primary tumor of the liver. Disease dissemination occurs through hematogenous routes and frequently involves the lungs, bone, adrenal glands, and pancreas. The patterns of the extrahepatic manifestations are diverse. Soft tissue metastasis is extremely rare and man...

journal_title：Journal of cancer research and therapeutics

authors： Michalaki V,Zygogianni A,Kouloulias V,Balafouta M,Vlachodimitropoulos D,Gennatas CG

更新日期：2011-01-01 00:00:00

abstract：Aims:Platinum-based chemotherapy is considered as the first-line treatment for nonsmall cell lung cancer (NSCLC) patients. However, platinum resistance and toxicity are major obstacles to its clinical applications. The two P-type ATPases ATP7A and ATP7B have been identified to play an essential role in the transport of...

journal_title：Journal of cancer research and therapeutics

authors： Li YQ,Zhang XY,Chen J,Yin JY,Li XP

更新日期：2018-01-01 00:00:00

abstract：Purpose:To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort. Patients and Methods:Eighty-four eyes of 62 consecutive patients with advanced refractory RB who received IAC were included in the study dur...

journal_title：Journal of cancer research and therapeutics

authors： Hua J,Gang S,Yizhou J,Jing Z

更新日期：2018-01-01 00:00:00

abstract：Background:Intractable ascites secondary to malignant disease deteriorates patients' quality of life. The purpose of this study was to evaluate the safety and efficacy of percutaneous peritoneovenous (Denver) shunt in treating intractable malignant ascites in cancer patients. Materials and Methods:Thirty-five patients...

journal_title：Journal of cancer research and therapeutics

authors： Tamagawa H,Aoyama T,Inoue H,Fujikawa H,Sawazaki S,Numata M,Sato T,Oshima T,Yukawa N,Morimoto M,Ueno M,Rino Y,Masuda M

更新日期：2020-12-01 00:00:00

abstract：Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

journal_title：Journal of cancer research and therapeutics

authors： Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

更新日期：2019-10-01 00:00:00

abstract：Purpose:Papillary thyroid carcinoma (PTC) has a strong propensity to metastasize to regional lymph nodes which increases the risk of local-regional relapse and affects the course of the disease. Molecular pathogenesis of lymph node metastasis (LNM) is not yet fully understood. Survivin, a multifunctionale molecule invo...

journal_title：Journal of cancer research and therapeutics

authors： Selemetjev S,Savin S,Paunovic I,Tatic S,Cvejic D

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The objective of the study is to investigate whether hospital-based transitional care can reduce the postoperative complication in patients who received enterostomy or not by pooling the published prospective clinical studies. MATERIALS AND METHODS:Prospective clinical studies related to hospital-based trans...

journal_title：Journal of cancer research and therapeutics

authors： Chen Y,Jiang J,Wu Y,Yan J,Chen H,Zhu X

更新日期：2016-10-01 00:00:00

abstract：Context:Familial adenomatous polyposis (FAP) is an autosomal dominant disorder. Colorectal cancer (CRC) has been implicated as the most common cause of death in FAP patients, especially in those with coexisting CRC at initial diagnosis (FAP-CRC). Aim:We aimed to determine the survival rate of FAP-CRC and the factors a...

journal_title：Journal of cancer research and therapeutics

authors： Mirinezhad SK,Moaddab SY,Bonyadi MJ,Shirmohammadi M,Eftekharsadat AT,Somi MH

更新日期：2019-01-01 00:00:00

abstract：Objective:The aim of this study is to probe in the inhibitory effects of ginsenoside Rg3 on the expression of hypoxia-induced factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in human gastric cancer cells. Materials and Methods:Human gastric cancer BGC823 cells were divided into the control group and e...

journal_title：Journal of cancer research and therapeutics

authors： Li B,Qu G

更新日期：2019-01-01 00:00:00

abstract：Purpose:The balance between T helper (Th) cells Th1- and Th2-related cytokines plays a key role in the clinical process of acute coronary syndrome (ACS) and type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT). The objective of this study was to assess the status of Th1/Th2 cytokines in patients with ACS...

journal_title：Journal of cancer research and therapeutics

authors： Zhao SL,Mo ZH,He HH,Zhao LL,Xie YH

更新日期：2018-06-01 00:00:00

abstract：:Symptoms of nausea and vomiting can present a diagnostic challenge for physicians. In this article, we report a patient who was found to have synchronous presentation of an ependymoma and pancreatic cancer. This case illustrates some of the diagnostic challenges in patients with constitutional symptoms. Furthermore, i...

journal_title：Journal of cancer research and therapeutics

authors： Chowdhry VK,Carter DA,Shapiro A

更新日期：2013-10-01 00:00:00

abstract：Introduction:The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established. We perform a single institutional retrospective study of CRT in terms of toxicity in elderly patients (age more than 60 years) as compared with young cohort (age <60 years)...

journal_title：Journal of cancer research and therapeutics

authors： Mohata S,Kumar HS,Sharma N,Jhakhar SL,Beniwal S,Harsh KK

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Our experience with endoscopic surgery for vascular leiomyomas of the nasal septum was reviewed. PATIENTS AND METHODS:All patients with vascular leiomyomas of the nasal septum who were treated with endoscopic surgery from May 1995 to June 2007 were reviewed retrospectively. RESULTS:Twelve patients had vascu...

journal_title：Journal of cancer research and therapeutics

authors： Chen HH,Wang QY,Zhou SH

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The serum level of Cyfra21-1 was always elevated in patients with nonsmall cell lung carcinoma. The aim of this meta-analysis was to evaluate the serum Cyfra21-1 as a biomarker in the diagnosis of nonsmall cell lung cancer (NSCLC). METHODS:All the articles associated with serum Cyfra21-1 in the diagnosis of ...

journal_title：Journal of cancer research and therapeutics

authors： Cui C,Sun X,Zhang J,Han D,Gu J

更新日期：2014-11-01 00:00:00

abstract：:Healthy breast tissue is sensitive to radiation fraction size, such that small changes in fraction size can lead to larger changes in radiation effects on these tissues. Conventional breast and/or chest wall irradiation uses 2 Gy daily fractions, for 5-6 weeks. Such a long treatment schedule has major implications on ...

journal_title：Journal of cancer research and therapeutics

authors： Bhattacharyya T,Mahajan R,Ghoshal S,Yadav BS,Rai B

更新日期：2015-04-01 00:00:00

abstract：:Understanding of cellular responses to ionizing radiation (IR) is essential for the development of predictive markers useful for assessing human exposure. Biological markers of exposure to IR in human populations are of great interest for assessing normal tissue injury in radiation oncology and for biodosimetry in nuc...

journal_title：Journal of cancer research and therapeutics

authors： Rezaeejam H,Shirazi A,Valizadeh M,Izadi P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The overall goal of this study is to use a bacterial toxin as drug delivery agents for chemotherapy drugs and overcome the development of resistance to these medicines. COR-L105 and MDA-MB 231 which are epithelial-like were used in this study. Cytotoxicity assays were performed by 3-(4, 5-dimethyl-2-thiazoly...

journal_title：Journal of cancer research and therapeutics

authors： Shekarsaraei AG,Hasannia S,Pirooznia N,Ataiee F

更新日期：2014-01-01 00:00:00

abstract：:Ectopic extrarenal renin-producing tumor is a rare disease with approximately 30 case reports in English literature. We herein present the first case of renin-producing germ cell tumors in the pineal apparatus and mediastinum. A 26-year-old man who had undergone craniotomy for the treatment of pineal tumor was found t...

journal_title：Journal of cancer research and therapeutics

authors： Uematsu M,Yokouchi H,Tanino Y,Munakata M

更新日期：2018-09-01 00:00:00

abstract：:Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

journal_title：Journal of cancer research and therapeutics

authors： Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

更新日期：2018-01-01 00:00:00

abstract：Purpose:The aim of this study was to classify bilateral breast cancers (BBCs) into two groups according to histopathological or molecular subtypes of the two breast diseases in each patient and to study their characteristics in relation to survival outcomes. Methods:Fifty-six BBC patients were enrolled in the study. T...

journal_title：Journal of cancer research and therapeutics

authors： Wang Y,Du C,Tu L,Luo F,Yan X

更新日期：2018-01-01 00:00:00