Abstract：
:Tumors arising from Meckel's diverticulum (MD) reported in the literature are mainly carcinoid and gastrointestinal stromal tumors. We herein report a rare case of adenocarcinoma arising from intestinal mucosa in an MD with multiple liver metastases at the onset of symptoms. A 57-year-old female complaining of bloody stool for 2 weeks was admitted to our hospital. Colonoscopy revealed massive bloody fluids but did not find any neoplasm. Computed tomography (CT) found a heterogeneous mass at the distal ileum and multiple liver metastases. A segmental ileal resection with local mesentery excision was performed to control the bleeding. During surgery, a tumor arising from a diverticulum in the antimesenteric border of ileum was observed. Histologic examination revealed moderate to poorly differentiated adenocarcinoma. Majority of the MD remain asymptomatic and are diagnosed incidentally during small bowel contrast study, laparoscopy or laparotomy done for unrelated conditions, or until complications arise from the diverticulum. Malignancies are reported to account for only 0.5%-3.2% of the complications. The occurrence of adenocarcinoma in an MD is exceedingly rare. In the few cases described so far, the prognosis of adenocarcinoma within an MD has been poor due to the advanced stage as seen at the time of surgery. Despite the availability of many publications, there is a little consensus concerning the management of an incidental finding of MD. Adenocarcinoma in an MD is extremely sporadic and prognosis has been reported as very poor. However, early diagnosis is challenging. When found incidentally during laparotomy, MD should be carefully examined and best treated with prophylactic resection.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Zhao Y,Yang X,Ye Ydoi
10.4103/jcrt.JCRT_124_17subject
Has Abstractpub_date
2017-01-01 00:00:00pages
878-881issue
5eissn
0973-1482issn
1998-4138pii
JCanResTher_2017_13_5_878_220463journal_volume
13pub_type
信件,评审abstract：:Foot is an uncommon site for chondrosarcoma and involvement of phalanges is extremely rare. Here, a case of low-grade chondrosarcoma of the distal phalanx of the right great toe in a 37-year-old male patient is being reported. The patient complained of gradual swelling of the right great toe and pain for last 2 years....
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章,评审
doi：10.4103/0973-1482.95191
更新日期：2012-01-01 00:00:00
abstract：:Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, soft tissue tumor. Its occurrence over face is very rare. We are presenting a case of giant DFSP over left cheek, which produces oncological, functional and esthetic challenges and deals by multidisciplinary team. We also reviewed the relevant ...
journal_title：Journal of cancer research and therapeutics
pub_type： 信件
doi：10.4103/0973-1482.139386
更新日期：2015-10-01 00:00:00
abstract：Purpose:The aim of the study is to study the feasibility of gamma-ray-detection-based precision dose measurement of 125I seed brachytherapy in solid water. Materials and Methods:Seven group 125I seeds with different activities were put into a hole in the center of solid water individually. Each group had ten seeds, an...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_522_18
更新日期：2019-01-01 00:00:00
abstract：Introduction:Cytokeratin fragment 21-1 (CYFRA21-1), a constituent of the intermediate filament protein is known to be elevated in cancer. In vitro cleavage of cytokeratin 19 (CK19) protein results in the release of it's fragments into the supernatants of premalignant cell lines. This study was designed with the aim to ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_893_17
更新日期：2020-04-01 00:00:00
abstract：:Hematological disorders, especially single lineage abnormalities, have been described in hyperthyroidism. Pancytopenia has been reported, without myelodysplastic syndrome or megaloblastic anemia. We studied the peripheral blood smear and the bone marrow aspiration and biopsy of a 65-year-old lady, who presented with p...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.31972
更新日期：2007-01-01 00:00:00
abstract：:Renal cell carcinoma is the most frequent kidney neoplasm, with a high tendency to metastasize. The occurrence of renal carcinoma metastasis to the head and neck region is extremely rare. Here we present one such case where the tongue metastasis was the initial presenting feature of disease. ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.110392
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.146056
更新日期：2015-07-01 00:00:00
abstract：Purpose:Glioblastoma (GBM) is characterized by early relapse and mortality. Treatment resistance could be a characteristic exhibited by pro-genitor neoplastic cells that reside in the subventricular zone (SVZ). This retrospective study was conducted to assess the correlation of SVZ doses and survival in patients with G...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_295_17
更新日期：2018-10-01 00:00:00
abstract：Background:The aim of this study is to determine the prognostic factors which affect both disease-free survival (DFS) and overall survival (OS) in thyroid papillary carcinoma with clinical lateral lymph node metastasis. Methods:One hundred and three papillary thyroid carcinomas diagnosed in adult patients received the...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_1011_16
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To assess the efficacy of radiation in the treatment of juvenile nasopharyngeal angiofibroma (JNA). MATERIALS AND METHODS:Data were retrieved for JNA treated with radiotherapy from 1987-2012. The demographics, treatment and outcome data were recorded in predesigned proforma. RESULTS:Data of 32 patients were r...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.150349
更新日期：2015-01-01 00:00:00
abstract：Purpose:The aim of this study was to classify bilateral breast cancers (BBCs) into two groups according to histopathological or molecular subtypes of the two breast diseases in each patient and to study their characteristics in relation to survival outcomes. Methods:Fifty-six BBC patients were enrolled in the study. T...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_997_17
更新日期：2018-01-01 00:00:00
abstract：Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_1277_16
更新日期：2019-01-01 00:00:00
abstract：AIM:The aim of this study was to analyze the demographic features, reproductive history and stage at disease presentation among the female breast cancer patients. DESIGN AND SETTING:The present prospective hospital-based study was conducted in Department of Radiation Oncology, University Teaching and Tertiary Referral...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.103518
更新日期：2012-07-01 00:00:00
abstract：AIM:The aim of this study was to determine the expression levels of serum ferritin (SF) and investigate the correlation between SF expression levels and clinical characteristics as well as the efficacy to platinum-based chemotherapy for advanced non-small cell lung cancer (NSCLC) patients. MATERIALS AND METHODS:Electr...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.139156
更新日期：2014-07-01 00:00:00
abstract：:Understanding of cellular responses to ionizing radiation (IR) is essential for the development of predictive markers useful for assessing human exposure. Biological markers of exposure to IR in human populations are of great interest for assessing normal tissue injury in radiation oncology and for biodosimetry in nuc...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章,评审
doi：10.4103/0973-1482.160912
更新日期：2015-07-01 00:00:00
abstract：:Chondroblastoma is a rare, benign tumor derived from chondroblasts, commonly presenting in the second decade of life. It is usually found in the epiphysis or apophysis of long bones; however, it may rarely affect flat bones like scapula. Occasionally a histologically typical chondroblastoma may exhibit an aggressive b...
journal_title：Journal of cancer research and therapeutics
pub_type： 信件
doi：10.4103/0973-1482.139387
更新日期：2015-07-01 00:00:00
abstract：:The novel coronavirus (COVID-19) pandemic has disrupted healthcare delivery across the globe. Cancer patients are at a higher risk of acquiring this infection due to their immunosuppressed state. Timely care of patients while ensuring safety of healthcare workers is need of the hour. We list few precautionary measures...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_405_20
更新日期：2020-04-01 00:00:00
abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.95201
更新日期：2012-01-01 00:00:00
abstract：:The aim of this work is to develop a wireless local area network (LAN) between different types of users (Radiation Oncologists, Radiological Physicists, Radiation Technologists, etc) for efficient patient data management and to made easy the availability of information (chair side) to improve the quality of patient ca...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.65236
更新日期：2010-04-01 00:00:00
abstract：:Papillary carcinoma is a well-differentiated type of thyroid carcinoma with very good overall prognosis. The commonest site of metastases is the lymph node, distant metastases being rare. We present a case of a 52-year-old male who presented with a solitary metastasis in the left para-sellar region and cavernous sinus...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章,评审
doi：10.4103/0973-1482.103528
更新日期：2012-07-01 00:00:00
abstract：Purpose:The balance between T helper (Th) cells Th1- and Th2-related cytokines plays a key role in the clinical process of acute coronary syndrome (ACS) and type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT). The objective of this study was to assess the status of Th1/Th2 cytokines in patients with ACS...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.194346
更新日期：2018-06-01 00:00:00
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journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.177214
更新日期：2016-04-01 00:00:00
abstract：CONTEXT:The critical condition of the cancer patient and the stringent medical procedures do not often warrant the accessibility of the patient for psychological evaluation. Therefore, the study is conceptualized to assess the psychological problems of caregivers, which in turn have their impact upon cancer patients. ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.146088
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:Management of recurrent presacral rectal cancer is often not amenable to curative surgery. The goal of this study is to evaluate the safety and efficacy of cyberknife stereotactic body radiotherapy (SBRT) in the management of presacral recurrences. MATERIALS AND METHODS:Between April 2003 and October 2008, 14 ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.92000
更新日期：2011-10-01 00:00:00
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journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.199390
更新日期：2018-01-01 00:00:00
abstract：Aim:This study was carried out to determine the fungal profile and antifungal susceptibility pattern in the brushing samples of candidiasis in patients with carcinoma of esophagus. Materials and Methods:The study was carried out in the Departments of Microbiology and Surgical Oncology of a regional cancer center from ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_581_18
更新日期：2020-12-01 00:00:00
abstract：Purpose:This study explored ultrasound grayscale ratios (USGRs) for differentiating markedly hypoechoic and anechoic minimal thyroid nodules. Materials and Methods:Longitudinal scan images of 193 markedly hypoechoic papillary thyroid microcarcinoma (PTMC) lesions from 184 patients were retrospectively reviewed using R...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_1031_17
更新日期：2018-01-01 00:00:00
abstract：AIM OF STUDY:To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver nanoparticles (SNs) to tumor growth in a murine model. MATERIALS AND METHODS:Sanazole (AK) and DOX were complexed with SNs, individually and in combination to obtain SN-AK, SN-DOX, and SN-AK-DOX....
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.148705
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Exfoliative cytology is an easy, economical, noninvasive, and feasible method for early detection and screening program of any premalignant or malignant lesion. In case of routine cytological procedure, classical Papanicolaou (PAP) stain is widely used while Romanowsky stains are sparingly used. Leishman-Gie...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/0973-1482.174548
更新日期：2017-10-01 00:00:00
abstract：Background:Squamous cell carcinoma (SCC) of the breast is an extremely rare tumor with vague natural behavior and treatment. The purpose of this study was to identify the clinicopathological features and treatment results of this rare type of breast cancer. Materials and Methods:The medical files of patients with SCC ...
journal_title：Journal of cancer research and therapeutics
pub_type： 杂志文章
doi：10.4103/jcrt.JCRT_303_17
更新日期：2019-07-01 00:00:00
