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Evaluating factors affecting survival in colon and rectum cancer: A prospective cohort study with 161 patients.

Abstract：

Context:Colorectal cancers are frequent among cancers of gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial. Aims:In this study, we aimed to compare survival in surgically treated rectum and colon cancers and determine the factors affecting survival. Subjects and Methods:The patients with colon and rectum cancer operated between 2009 and 2013 were examined retrospectively using prospective database. Patients were categorized as colon and rectum according to the tumor's location. Survival was identified as the primary outcome. Kaplan-Meier survival analysis and log-rank tests in survival assessment were used. Results:One hundred and sixty-one patients with a mean age of 62.8 ± 12.7 years were included in the study. Male/female ratio was 1.6. Colon and rectum patients were counted as 92 (%57.1) and 69 (%42.9), respectively. Both groups were similar in demographic data (P > 0.05). It was observed that in 46 months (mean) of follow-up, 39.7% (n: 64) died, and 60.3% (n: 97) survived. Median survival time was 79 months, and 5-year cumulative survival rate was 60.8%. Five-year cumulative survival rates in stages for 1, 2, 3 and 4 were 88.2%, 64.7%, 48.5%, and 37.0%, respectively. It was noted that median survival time for colon cancer was 78 months and for rectum cancer was 79 months. Five-year cumulative survival rates for colon and rectum cancers were calculated as 56.7% and 63.4%, respectively. There were no significant differences in colon and rectum cancers in the means of survival rate (P: 0.459). Conclusions:While location of colorectal cancers shows no significant effect on survival, treatment in the early stages increases survival rate.

journal_name

J Cancer Res Ther

journal_title

Journal of cancer research and therapeutics

authors

Kalcan S,Sisik A,Basak F,Hasbahceci M,Kilic A,Kosmaz K,Kivanc AE,Kudas I,Bas G,Alimoglu O

doi

10.4103/0973-1482.199390

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

416-420

issue

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2018_14_2_416_199390

journal_volume

pub_type

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Evaluating factors affecting survival in colon and rectum cancer: A prospective cohort study with 161 patients.