Fungal profile and antifungal susceptibility pattern of candidiasis in esophageal cancer patients.

Abstract:

Aim:This study was carried out to determine the fungal profile and antifungal susceptibility pattern in the brushing samples of candidiasis in patients with carcinoma of esophagus. Materials and Methods:The study was carried out in the Departments of Microbiology and Surgical Oncology of a regional cancer center from January 2017 to December 2017. Samples were collected under all aseptic precaution and Clinical Laboratory Standards Institute guidelines 2017 was followed for antifungal susceptibility testing. Results:A total of 132 endoscopy brushing samples were collected from histological proven esophageal cancer patients and processed for fungal culture. Of which, 75 (56.81%) samples showed culture positivity and were recruited. Candida albicans in 40 (53.33%), Candida krusei in 25 (33.33%), Candida tropicalis in 7 (9.33%), and Candida glabrata in 3 (4%) patients were seen. Among the 40 C. albicans isolates, all were sensitive to caspofungin - 40 (100%), 34 (85%) showed sensitivity to fluconazole, and 32 (80%) showed sensitivity to flucytosine. C. krusei and C. tropicalis showed 100% sensitivity to caspofungin, and C. glabrata isolates showed 100% resistance to caspofungin and 80% resistance to Amphotericin B. Conclusion:The present study revealed the emergence of multidrug-resistant, nonalbicans Candida isolates in cancer esophagus patients with candidiasis in northeast India.

journal_name

J Cancer Res Ther

authors

Talukdar A,Barman R,Sarma A,Krishnatreya M,Sharma JD,Kataki AC

doi

10.4103/jcrt.JCRT_581_18

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

S209-S212

issue

Supplement

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2020_16_8_209_264223

journal_volume

16

pub_type

杂志文章
  • A case of invasive papillary breast carcinoma: Fierce façade with favorable prognosis.

    abstract::Invasive papillary carcinoma of the breast is a rare, distinct variant comprising approximately less than 1-2% of all newly diagnosed cases of breast carcinoma and is usually found in postmenopausal women with a more favorable prognosis. We report an unusual case in a 45-year-old perimenopausal female who came with a ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.154086

    authors: Vani D,Geetanjali S,Punja GM,Bharathi M

    更新日期:2015-10-01 00:00:00

  • Impact of Gleason pattern up gradation after radical prostatectomy for carcinoma prostate patients with low biopsy score (≤ 6).

    abstract:CONTEXT:Biopsy Gleason score (b-GS) is often different from the Gleason score obtained after analysis of radical prostatectomy (RP) specimen (rp-GS). Upgradation has an important implication in decision making for cancer prostate management, and is the focus of this study. AIM:To evaluate Gleason score upgradation aft...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.92021

    authors: Kulkarni JN,Valsangkar RS,Jadhav YR,Singh DP

    更新日期:2011-10-01 00:00:00

  • Lower serum levels of bilirubin in the newly diagnosed lung cancer patients: A case-control study in China.

    abstract:PURPOSE:A few prospective studies demonstrated that bilirubin levels were inversely associated with the risk of lung cancer. However, the retrospective study about the relationship between bilirubin levels and lung cancer in China was not available. So, we want to know whether there has a difference in serum bilirubin ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.168179

    authors: Song Q,Wang B,Wang S,Zhang YM,Chen WH

    更新日期:2015-10-01 00:00:00

  • ATP7B rs9535826 is associated with gastrointestinal toxicity of platinum-based chemotherapy in nonsmall cell lung cancer patients.

    abstract:Aims:Platinum-based chemotherapy is considered as the first-line treatment for nonsmall cell lung cancer (NSCLC) patients. However, platinum resistance and toxicity are major obstacles to its clinical applications. The two P-type ATPases ATP7A and ATP7B have been identified to play an essential role in the transport of...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_890_17

    authors: Li YQ,Zhang XY,Chen J,Yin JY,Li XP

    更新日期:2018-01-01 00:00:00

  • Knockdown of alpha-fetoprotein expression inhibits HepG2 cell growth and induces apoptosis.

    abstract:Aims:To explore the biological roles of alpha-fetoprotein (AFP), a tumor-associated antigen in human hepatocellular carcinoma (HCC). Materials and Methods:After knockdown of AFP in HepG2 cells by transfection of specific Stealth™ RNAi, the expression of AFP were detected by reverse transcription polymerase chain react...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.180681

    authors: Yang X,Chen L,Liang Y,Si R,Jiang Z,Ma B,Gao P

    更新日期:2018-09-01 00:00:00

  • Factors affecting quality of life of cervical cancer patients: A multivariate analysis.

    abstract:Objective:The aim of good management for cancer survivors should not be limited to only clinical care, but rather it should also include best quality of life (QOL). The objective of this study was to find out various factors affecting QOL in cervical cancer patients so that by modifying these factors, the best QOL can ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_1028_17

    authors: Singh U,Verma ML,Rahman Z,Qureshi S,Srivastava K

    更新日期:2019-10-01 00:00:00

  • Quadrivalent human papillomavirus recombinant vaccine: the first vaccine for cervical cancers.

    abstract::Gardasil is the first quadrivalent human papillomavirus (HPV)-types 6, 11, 16, 18 recombinant vaccine approved by the FDA on June 8, 2006. It induces genotype-specific virus-neutralizing antibodies and prevents infection with HPV. Various clinical trials demonstrated a reduction in the incidence of vaccine-type-specif...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.34686

    authors: Sharma R,Sharma CL

    更新日期:2007-04-01 00:00:00

  • Effect of gemcitabine on the uptake of (18)F-fluorodeoxyglucose and (18)F-fluorothymidine in lung adenocarcinoma A549 cells and the animal tumor model.

    abstract:BACKGROUND:Gemcitabine is the first-line drug for nonsmall cell lung cancer, and 18F-fluorodeoxyglucose. (18F-FDG) and 18F-fluorothymidine. (18F-FLT) are positron emission tomography. (PET) imaging agents. The aim of this study was to explore the effect of gemcitabine on the uptake of 18F-FDG and 18F-FLT in A549 cells ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.147713

    authors: Zhang B,Deng SM,Guo LC,Dong JJ,Zhu YB,Gao Y,Wang ZX,Cho WC

    更新日期:2016-01-01 00:00:00

  • Autophagy facilitates anticancer effect of 5-fluorouracil in HCT-116 cells.

    abstract:Aim of Study:The roles of autophagy performed in chemotherapy-induced cell death or proliferation inhibition were still in debate. In this study, we aimed to disclose the function of autophagy in chemotherapy of HCT-116 colon cells. Materials and Methods:Pharmacological and genetic methods were applied to induce and i...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.204898

    authors: Yang JW,Zhang QH,Liu T

    更新日期:2018-12-01 00:00:00

  • Cylindric cell carcinoma of the base of the tongue: a rare variant of squamous cell carcinoma.

    abstract::Cylindric cell carcinomas (transitional cell carcinomas) are a rare and distinct histopathological entity presenting in the head and neck region. They have been known by myriads of nomenclature like cylindric carcinomas, nonkeratinizing sinonasal carcinoma, papillary carcinoma, cylindrical or columnar cell carcinoma, ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.52795

    authors: Kumar M,Bahl A,Sharma DN,Sharma R,Gupta R,Ahmed S,Julka PK,Rath GK

    更新日期:2009-04-01 00:00:00

  • Survival and failure patterns in atypical and anaplastic meningiomas: A single-center experience of surgery and postoperative radiotherapy.

    abstract:INTRODUCTION:Intracranial meningiomas are the second most common tumor of the CNS. The high-grade tumors are atypical and malignant meningioma comprising 5-7% and 1-3% of all meningiomas. The high-grade meningioma have an aggressive histopathological and clinical behavior. MATERIALS AND METHODS:We retrospectively revi...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 临床试验,杂志文章

    doi:10.4103/0973-1482.151426

    authors: Kumar N,Kumar R,Khosla D,Salunke PS,Gupta SK,Radotra BD

    更新日期:2015-10-01 00:00:00

  • Clinicoepidemiological analysis of female breast cancer patients in Kashmir.

    abstract:AIM:The aim of this study was to analyze the demographic features, reproductive history and stage at disease presentation among the female breast cancer patients. DESIGN AND SETTING:The present prospective hospital-based study was conducted in Department of Radiation Oncology, University Teaching and Tertiary Referral...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.103518

    authors: Wani SQ,Khan T,Wani SY,Koka AH,Arshad S,Rafiq L,Mqabool LM,Afroz F

    更新日期:2012-07-01 00:00:00

  • Clear cell hepatocellular carcinoma: Back to the basics for diagnosis.

    abstract::Hepatocellular carcinoma (HCC) is a common cancer world-wide with a higher incidence in Asia. Clear cell variant of HCC (CCHCC) has a frequency ranging from 0.4% to 37%. The presence of 90-100% clear cells is rare. In the present case, a 35-year-old female patient presented with fever and a large abdominal mass in the...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.136041

    authors: Sakhuja P,Mishra PK,Rajesh R,Sharma AK,Gondal R,Singh M

    更新日期:2015-07-01 00:00:00

  • Adult neuroblastoma of the ovary: a rare tumor with review of literature.

    abstract::Neuroblastoma is a tumor of pediatric age group and is extremely rare in adults. Common sites involved in adults are almost similar to that seen in children like retroperitoneum, adrenal gland, pelvis and mediastinum. Ovarian neuroblastoma has never been reported in the literature before. We, hereby, present a case of...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.73367

    authors: Singh M,Arora P,Singh S,Bohara S,Khurana N,Zutshi V,Kumar R

    更新日期:2010-07-01 00:00:00

  • Primary papillary thyroid carcinoma previously treated incompletely with radiofrequency ablation.

    abstract::Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.73328

    authors: Kim HY,Ryu WS,Woo SU,Son GS,Lee ES,Lee JB,Bae JW

    更新日期:2010-07-01 00:00:00

  • Chondrosarcoma of the distal phalanx of the right great toe: report of a rare malignancy and review of literature.

    abstract::Foot is an uncommon site for chondrosarcoma and involvement of phalanges is extremely rare. Here, a case of low-grade chondrosarcoma of the distal phalanx of the right great toe in a 37-year-old male patient is being reported. The patient complained of gradual swelling of the right great toe and pain for last 2 years....

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章,评审

    doi:10.4103/0973-1482.95191

    authors: Mondal SK

    更新日期:2012-01-01 00:00:00

  • Evaluation of clinical process in osteosarcoma patients treated with chemotherapy including cisplatin, adriamycin, ifosfamide, and etoposide and determination of the treatment sequels in a long-term 11-year follow-up.

    abstract:AIM:The aim of this study was to evaluate the effect of adding etoposide and ifosfamide chemotherapy drugs to treatment regimen of patients affected with osteosarcoma and to determine the clinical process and response to treatment during a follow-up period of 11 years. MATERIALS AND METHODS:Forty patients with osteosa...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.199447

    authors: Aznab M,Hematti M

    更新日期:2017-04-01 00:00:00

  • Neoadjuvant chemotherapy in patients with locally advanced breast cancer: A pilot-observational study.

    abstract:BACKGROUND:Locally advanced breast cancer (LABC) remains major clinical issue with regard to selection and duration of therapy since many years. Neoadjuvant chemotherapy (NACT) is multimodality program, established to treat LABC. Many research tasks are ongoing to develop specific neoadjuvant chemotherapy regimen with ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.146056

    authors: Dodiya HG,Brahmbhatt AP,Khatri PK,Kaushal AM,Vijay DG

    更新日期:2015-07-01 00:00:00

  • Evaluation of breast lesions by digital mammography and ultrasound along with fine-needle aspiration cytology correlation.

    abstract:Introduction:Screening and diagnostic efforts for breast cancer are critical because the disease has a high rate of successful outcomes with early identification and treatment. The mammography (MG) and Ultrasonography/ ultrasound (USG) are individually effective diagnostic modalities for detection of breast pathologies...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.191053

    authors: Tiwari P,Ghosh S,Agrawal VK

    更新日期:2018-07-01 00:00:00

  • Experience of wireless local area network in a radiation oncology department.

    abstract::The aim of this work is to develop a wireless local area network (LAN) between different types of users (Radiation Oncologists, Radiological Physicists, Radiation Technologists, etc) for efficient patient data management and to made easy the availability of information (chair side) to improve the quality of patient ca...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.65236

    authors: Mandal A,Asthana AK,Aggarwal LM

    更新日期:2010-04-01 00:00:00

  • Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors.

    abstract:AIM:To study the role of neoadjuvant imatinib mesylate in downsizing tumors in patients with locally advanced nonmetastatic gastrointestinal stromal tumors (GISTs), thus improving the possibility of complete resection. MATERIALS AND METHODS:We used neoadjuvant imatinib in six patients with locally advanced GISTs, at a...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 临床试验,杂志文章

    doi:10.4103/0973-1482.59905

    authors: Seshadri RA,Rajendranath R

    更新日期:2009-10-01 00:00:00

  • Primary spinal glioblastoma treated with adjuvant radiation and temozolomide: Report of two cases.

    abstract::Primary spinal glioblastoma multiforme (GBM) is a rare entity, which is invariably associated with poor outcome. Standard treatment is surgery followed by post-operative radiotherapy. Due to paucity of cases role of chemotherapy is investigational. We intend to report two cases of primary spinal GBM treated with radia...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件

    doi:10.4103/0973-1482.137998

    authors: Mallick S,Madan R,Julka PK

    更新日期:2015-07-01 00:00:00

  • Off-label use of anti-cancer drugs in India: to be or not to be!

    abstract:BACKGROUND:Administering drugs outside the terms of their official labeling is called off-label use. In the West, oncologists often use drugs off-label, which offers several advantages especially while treating patients with multiple comorbidities or advanced cancer. The practice of off-label prescribing of anticancer ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.80455

    authors: Gota V,Patial P

    更新日期:2011-01-01 00:00:00

  • In vivo dose estimations through transit signal measured with thimble chamber positioned along the central axis at electronic portal imaging device level in medical linear accelerator in carcinoma of the middle-third esophagus patients undergoing three-di

    abstract:Objective:This study presents a method to estimate midplane dose (Diso, transit) in vivo from transit signal (St) measured with thimble ionization chamber in cancer of the middle-third esophagus patients treated with three-dimensional radiotherapy (RT). This detector is positioned at the level of electronic portal imag...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_278_17

    authors: Kumar PS,Banerjee S,Arun Kumar ES,Srinivas C,Vadhiraja BM,Saxena PU,Ravichandran R,Kasturi DP

    更新日期:2018-01-01 00:00:00

  • Identification of significant ego networks and pathways in rheumatoid arthritis.

    abstract:Objective:The objective of this paper is to identify ego networks and pathways in rheumatoid arthritis (RA) based on EgoNet algorithm and pathway enrichment analysis. Materials and Methods:The ego networks were identified based on the EgoNet algorithm which was comprised four steps: inputting gene expression data and ...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.189250

    authors: Zhou WZ,Miao LG,Yuan H

    更新日期:2018-12-01 00:00:00

  • The prognostic factors for clinical N1b patients in thyroid papillary carcinoma.

    abstract:Background:The aim of this study is to determine the prognostic factors which affect both disease-free survival (DFS) and overall survival (OS) in thyroid papillary carcinoma with clinical lateral lymph node metastasis. Methods:One hundred and three papillary thyroid carcinomas diagnosed in adult patients received the...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_1011_16

    authors: Yuksel UM,Turanli S,Acar Y,Berberoglu U

    更新日期:2019-07-01 00:00:00

  • Intra-arterial chemotherapy as second-line treatment for advanced retinoblastoma: A 2-year single-center study in China.

    abstract:Purpose:To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort. Patients and Methods:Eighty-four eyes of 62 consecutive patients with advanced refractory RB who received IAC were included in the study dur...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/jcrt.JCRT_722_17

    authors: Hua J,Gang S,Yizhou J,Jing Z

    更新日期:2018-01-01 00:00:00

  • Radiation recall phenomenon presenting as myositis triggered by carboplatin plus paclitaxel and related literature review.

    abstract::While most case reports to date are radiation recall dermatitis, radiation recall myositis, which is a distinct form of radiation recall phenomenon caused by carboplatin plus paclitaxel, has not been reported. We treated a 57-year-old female patient who suffered from recurrent cervical cancer. When the patient develop...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 信件,评审

    doi:10.4103/0973-1482.146090

    authors: Maeng CH,Park JS,Lee SA,Kim DH,Yun DH,Yoo SD,Kim HS,Chon J

    更新日期:2014-10-01 00:00:00

  • Low titer of antibody against Toxoplasma gondii may be related to resistant to cancer.

    abstract:CONTEXT:Toxoplasma gondii is a protozoan parasite with a world-wide distribution. However, the majority of infected cases remain symptomless. There are raising scientific evidences indicating that parasitic infections induce antitumor activity against certain types of cancers. The inhibitory effect of T. gondii on canc...

    journal_title:Journal of cancer research and therapeutics

    pub_type: 杂志文章

    doi:10.4103/0973-1482.144638

    authors: Seyedeh MS,Nahid S,Nahid M,Shima DP,Morteza Y,Hossein YD

    更新日期:2015-04-01 00:00:00

  • Primary extraneural ependymoma of the broad ligament: A rare entity.

    abstract::Extraneural broad ligament ependymoma is a rare entity. Herein, we present a case of unusually large broad ligament ependymoma in a 32-year-old female with pain and lump in the lower abdomen. Contrast-enhanced computed tomography abdomen revealed multiple heterogeneously enhancing pelvic masses with lobulated surface ...

    journal_title:Journal of cancer research and therapeutics

    pub_type:

    doi:10.4103/jcrt.JCRT_672_17

    authors: Kumari A,Diwaker P,Gogoi P,Arora VK,Garg PK,Pandey R

    更新日期:2019-10-01 00:00:00