Abstract:
:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated with the pharmacodynamic interaction with a concomitant drug. The present case indicates that erlotinib-induced ILD was associated with a high plasma concentration of erlotinib. Oncologists should be aware of the possibility of ILD induced by erlotinib, especially for patients with co-morbidities.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Tsubata Y,Hamada A,Sutani A,Isobe Tdoi
10.4103/0973-1482.95201subject
Has Abstractpub_date
2012-01-01 00:00:00pages
154-6issue
1eissn
0973-1482issn
1998-4138pii
JCanResTher_2012_8_1_154_95201journal_volume
8pub_type
杂志文章abstract:CONTEXT:The diagnosis of malignant and potentially malignant epithelial lesions of oral mucosa cannot be based solely on clinical findings. The histologic evaluation of a representative biopsy specimen thus becomes necessary. The site for biopsy, however, is always a subjective choice that sometimes raises doubts about...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,收录出版
doi:10.4103/0973-1482.137957
更新日期:2014-07-01 00:00:00
abstract:AIM:B-cell chronic lymphocytic leukemia (B-CLL) is the most common adult leukemia in the Western world and characterized by the progressive expansion of malignant B lymphocytes in peripheral blood. In spite of advances in sciences to recognize the number of effective agents for the treatment of chronic lymphocytic leuk...
journal_title:Journal of cancer research and therapeutics
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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更新日期:2014-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2017-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2014-12-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.177504
更新日期:2016-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.164705
更新日期:2016-07-01 00:00:00
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更新日期:2008-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.183561
更新日期:2018-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2019-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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doi:10.4103/0973-1482.113352
更新日期:2013-04-01 00:00:00
abstract::Ectopic extrarenal renin-producing tumor is a rare disease with approximately 30 case reports in English literature. We herein present the first case of renin-producing germ cell tumors in the pineal apparatus and mediastinum. A 26-year-old man who had undergone craniotomy for the treatment of pineal tumor was found t...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
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更新日期:2018-09-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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doi:10.4103/0973-1482.139601
更新日期:2015-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2017-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2012-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2015-10-01 00:00:00
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更新日期:2017-01-01 00:00:00
abstract::The ameloblastic fibroma (AF) is an uncommon odontogenic tumor that may present an aggressive behavior and may have potential for malignant transformation. Ghost cell differentiation within AF is extremely rare. There are only seven cases in English literature in which ghost cells are found in AF but all these previou...
journal_title:Journal of cancer research and therapeutics
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2019-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2018-12-01 00:00:00
abstract::Renal cell carcinoma, unclassified constitute about 3-4% of all renal carcinomas. It essentially is a tumor where more than morphological variants or subtypes are seen in a single tumor. Usually there is a mixture of 2-3 different types. However, in this particular case there were at least 5 different types of morphol...
journal_title:Journal of cancer research and therapeutics
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abstract::Acinic cell carcinoma (ACC) is a low-grade malignant salivary gland neoplasm that comprises approximately 17% of primary salivary gland malignancies or about 6% of all salivary gland neoplasms. The most common intraoral sites are the buccal mucosa, lips, and palate. The diagnosis of ACC frequently presents difficultie...
journal_title:Journal of cancer research and therapeutics
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更新日期:2020-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00