Comparison of primary radiation versus robotic surgery plus adjuvant radiation in high-risk prostate cancer: a single center experience.

Abstract:

OBJECTIVE:The objective of this study was to compare robotic-prostatectomy plus adjuvant radiation therapy (RPRAT) versus primary RT for high-risk prostate cancer (HRPCa). MATERIALS AND METHODS:A retrospective chart review was performed for the HRPCa patients treated in our institution between 2000 and 2010. One hundred and twenty-three patients with high-risk disease were identified. The Chi-square test and Fisher's exact test were used to compare local control and distant failure rates between the two treatment modalities. For prostate-specific antigen comparisons between groups, Wilcoxon rank-sum test was used. RESULTS:The median follow-up was 49 months (range: 3-138 months). Local control, biochemical recurrence rate, distant metastasis, toxicity, and disease-free survival were similar in the two groups. CONCLUSIONS:Primary RT is an excellent treatment option in patients with HRPCa, is equally effective and less expensive treatment compared with RPRAT. A prospective randomized study is required to guide treatment for patients with HRPCa.

journal_name

J Cancer Res Ther

authors

Singh P,Desai P,Arora S,Pham AH,Wernicke AG,Smith M,Nori D,Clifford Chao KS,Parashar B

doi

10.4103/0973-1482.139601

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

191-4

issue

1

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2015_11_1_191_139601

journal_volume

11

pub_type

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