Abstract:
:Interstitial permanent radioactive seed implantation delivers a high local dose to tumors and sharply drops off at surrounding normal tissues. Radioactive seeds implanted via ultrasound or computed tomography (CT) guidance are minimally invasive and facilitate quick recovery. Transrectal ultrasound-guided 125I seed implantation assisted by a transperineal plane template is standard for early-stage prostate carcinoma, with a highly consistent target volume dose distribution. The postplan dose evaluation is consistent with the preplan evaluation. Until now, there was no workflow for seed implantation elsewhere in the body, and it was difficult to effectively preplan for seed implantation because of patients' position changes, organ movement, and bone structure interference. Along with three-dimensional (3D) printing techniques and seed implantation planning systems for brachytherapy, coplanar and X Y axis coordinate templates were created, referred to as 3D-printed coplanar templates (3D-PCT). 125I seed implantation under CT guidance with 3D-PCT assistance has been very successful in some carcinomas. Preplanning was very consistent with postplanning of the gross tumor volume. All needles are kept parallel for 3D-PCT, with no coplanar needle rearrangement. No standard workflow for 3D-PCT-assisted seed implantation exists at present. The consensus topics for CT-assisted guidance compared to 3D-PCT-assisted guidance for seed implantation are as follows: Indications for seed implantation, preplanning, definition of radiation doses and dosimetry evaluation, 3D-PCT workflow, radiation protection, and quality of staff. Despite current data supporting 125I seed implantation for some solid carcinomas, there is a need for prospectively-randomized multicenter clinical trials to gather strong evidence for using 125I seed implantation in other solid carcinomas.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Wang J,Chai S,Wang R,Zheng G,Zhang K,Huo B,Huo X,Jiang Y,Ji Z,Jiang P,Peng Rdoi
10.4103/jcrt.JCRT_434_19subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1430-1434issue
7eissn
0973-1482issn
1998-4138pii
JCanResTher_2019_15_7_1430_275556journal_volume
15pub_type
杂志文章,评审abstract::Primary spinal glioblastoma multiforme (GBM) is a rare entity, which is invariably associated with poor outcome. Standard treatment is surgery followed by post-operative radiotherapy. Due to paucity of cases role of chemotherapy is investigational. We intend to report two cases of primary spinal GBM treated with radia...
journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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更新日期:2018-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.146056
更新日期:2015-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_296_17
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,随机对照试验
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更新日期:2018-09-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
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pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
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