Abstract:
Purpose:We aimed to report the experience of intraoperative electron radiation therapy (IOERT) with Mobetron (Intraop Medical Incorporated, Santa Clara, CA, USA) as a partial breast irradiation (PBI) for patients with early-stage breast cancer and explanation of IOERT application and present early clinical and cosmetic result. Materials and Methods:Between November 2012 and February 2014, in Ankara Oncology Hospital, Radiation Oncology Clinic, was performed IOERT as a PBI with a single dose of 21 Gy for 21selected patients. Median tumor size was 1.5 cm (range, 0.6-2.8 cm). Median treatment duration was 2.04 min (range, 1.26-2.44 min). According to final pathology, two patients were found to have close margin and mastectomy was applied. Three cases (two were N1 mic and one case had perineural invasion and tumor size was >2 cm) received whole breast irradiation. Results:Median follow-up time was 3 years (range, 26-42 months). One patient died because of nonbreast cancer reason, all of the other patients (except one) alive without disease. There was no Grade 3 or 4 toxicities related to the IOERT. Good or excellent cosmesis was revealed 79% (15/19) and 95% (18/19), by physician and patient, respectively. Conclusion:IOERT, for patients with early-stage breast cancer as a part of breast-conserving treatment, offer patients better cosmetic results with less skin toxicity and increases comfort of patients by shortening duration of treatment time.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Avci GG,Güney Y,Küçükpilakci B,Çalikoğlu T,Gülçelik MA,Özaslan Cdoi
10.4103/jcrt.JCRT_191_17subject
Has Abstractpub_date
2019-07-01 00:00:00pages
994-998issue
5eissn
0973-1482issn
1998-4138pii
JCanResTher_2019_15_5_994_244441journal_volume
15pub_type
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