Clinical significance of adiponectin expression in colon cancer patients.

abstract：:Often in metastatic disease, biopsy confirmation of suspicious central nervous system (CNS) lesions is not mandated according to the American College of Radiology, International Radiosurgery Association, and the National Comprehensive Cancer Network. We present a case of an individual who was thought to have metastati...

journal_title：Journal of cancer research and therapeutics

authors： Gestaut MM,Strober ED,Jhavar SG,Patel MK

更新日期：2017-10-01 00:00:00

abstract：:Primary vascular leiomyosarcoma (LMS) is a rare tumor accounting for 2% of all LMSs, with the most common site being inferior vena cava (IVC). Overall prognosis is poor, with median survival of 2 years only. We present four cases diagnosed with LMS of IVC, treated with surgery, radiation and chemotherapy. The diagnosi...

journal_title：Journal of cancer research and therapeutics

authors： Kapoor R,Bansal A,Sharma SC

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Measuring the microvascular and mast cell density in squamous cell carcinoma of lung and correlating them with the patient survival may be helpful to guide the use of cancer chemotherapeutic agents which target molecular mechanisms of tumour angiogenesis and mast cells. MATERIALS AND METHODS:It was an obser...

journal_title：Journal of cancer research and therapeutics

authors： Ullah E,Nagi AH,Ashraf M

更新日期：2013-10-01 00:00:00

abstract：Background:Baicalein is an active compound extracted from the roots of Scutellaria baicalensis georgi, which is widely and traditionally used in the anticancer therapy. Notch signaling pathway is usually abnormally activated in kinds of human cancers. The aim of the present study is to investigate the antitumor effects...

journal_title：Journal of cancer research and therapeutics

authors： Lian H,Hui Y,Xiaoping T,Wei T,Jiyi X,Xiaolan Y

更新日期：2019-10-01 00:00:00

abstract：Purpose:Programmed death ligand-1 (PD-L1) is the main ligand for programmed death-1 (PD-1), and is one of the major targets for cancer immunotherapy. Only a few studies are available for the clinical significance of PD-1/PD-L1 in nasopharyngeal carcinoma (NPC). There is a controversial association between PD-L1 express...

journal_title：Journal of cancer research and therapeutics

authors： Sahinli H,Akyürek N,Yılmaz M,Kandemir O,Duran AO,Kulaçoǧlu S,Uçar G,Acar E,Özet A,Öksüzoǧlu OBÇ,Özdemir NY

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Free radical associated damages play a major role in causation of cancer in tobacco habituates. The free radicals released by tobacco bring about alterations in antioxidant levels in humans and these free radical associated damages are reflected through antioxidant enzyme activities in blood. AIMS:To evaluate ...

journal_title：Journal of cancer research and therapeutics

authors： Naga Sirisha CV,Manohar RM

更新日期：2013-04-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) a member of the heat shock proteins (HSPs) family, is an adenosine triphosphate dependent molecular chaperone protein, which integrates multiple oncogenic pathways. Clinically, encouraging results have been demonstrated in melanoma, acute myeloid leukemia, castrate refractory prostate can...

journal_title：Journal of cancer research and therapeutics

authors： Routray S,Sunkavalli A,Swain N,Shankar AA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Wide variations are seen in clinical practice with respect to response to concurrent chemo radiation among cervical cancer patients. Fall in serum glutathione (GSH) level directly correlates with early response to treatment. Whether this early response translates to a better long term outcome is the subject ...

journal_title：Journal of cancer research and therapeutics

authors： Narasappa MG,Gururajachar JM,Chokkanna VK,Somashekar M

更新日期：2016-07-01 00:00:00

abstract：Aim of Study:Prostate cancer (PCa) is one of the most common cancers among men and has become a significant health problem in developing and developed countries. Prostate-specific antigen (PSA) is a useful marker for screening and monitoring the patients. In this study, the author aimed to detect the prevalence of PCa ...

journal_title：Journal of cancer research and therapeutics

authors： Çalışkan S

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...

journal_title：Journal of cancer research and therapeutics

authors： Ahmed I,Ferro A,Baby R,Malhotra J,Cohler A,Langenfeld J,Aisner J,Zou W,Jabbour SK

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:This study aims to explore the application of Choi's typing method in the immunological typing of diffuse large B-cell lymphoma (DLBCL) in Xinjiang Autonomous Region and its prognostic significance. MATERIALS AND METHODS:Seventy-eight cases of DLBCL tumor tissues from Xinjiang were collected to detect the ex...

journal_title：Journal of cancer research and therapeutics

authors： Jia CD,Liang LP,Yang LL,Yue N,Zhao F,Bai JP

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To assess the efficacy of radiation in the treatment of juvenile nasopharyngeal angiofibroma (JNA). MATERIALS AND METHODS:Data were retrieved for JNA treated with radiotherapy from 1987-2012. The demographics, treatment and outcome data were recorded in predesigned proforma. RESULTS:Data of 32 patients were r...

journal_title：Journal of cancer research and therapeutics

authors： Mallick S,Benson R,Bhasker S,Mohanti BK

更新日期：2015-01-01 00:00:00

abstract：Objective:The association between asthma and the risk of prostate cancer remains elusive. We aimed to evaluate the relationship between asthma and the onset of prostate cancer. Methods:We searched PubMed, Embase, and Cochrane databases for articles that assessed the association of asthma with the risk of prostate canc...

journal_title：Journal of cancer research and therapeutics

authors： Li W,Mao S,Tu M,Ge X,Li K,Xie F,Song Y,Miao Y

更新日期：2018-09-01 00:00:00

abstract：Purpose:The aim of this study was to classify bilateral breast cancers (BBCs) into two groups according to histopathological or molecular subtypes of the two breast diseases in each patient and to study their characteristics in relation to survival outcomes. Methods:Fifty-six BBC patients were enrolled in the study. T...

journal_title：Journal of cancer research and therapeutics

authors： Wang Y,Du C,Tu L,Luo F,Yan X

更新日期：2018-01-01 00:00:00

abstract：:Melanoma is rare in children, but its incidence appears to be increasing. Melanoma accounts for the highest mortality among all skin cancer types. This disease is characterized by high-grade malignancy, easy metastasis, poor prognosis, and high death rate. Melanoma in children may be biologically different from that i...

journal_title：Journal of cancer research and therapeutics

authors： Yang Y,Qian Q

更新日期：2014-11-01 00:00:00

abstract：:Invasive papillary carcinoma of the breast is a rare, distinct variant comprising approximately less than 1-2% of all newly diagnosed cases of breast carcinoma and is usually found in postmenopausal women with a more favorable prognosis. We report an unusual case in a 45-year-old perimenopausal female who came with a ...

journal_title：Journal of cancer research and therapeutics

authors： Vani D,Geetanjali S,Punja GM,Bharathi M

更新日期：2015-10-01 00:00:00

abstract：:Prostate cancer, one of the most common male malignancies with an increasing incidence in the recent years, requires the development of new methods of treatment. One of the most debated subjects is the tumor-associated macrophages (TAM). Although, the pathophysiological mechanisms are still a subject of intense resear...

journal_title：Journal of cancer research and therapeutics

authors： Nenu I,Gafencu GA,Popescu T,Kacso G

更新日期：2017-07-01 00:00:00

abstract：Purpose:To evaluate the effectiveness and complications of intra-arterial chemotherapy (IAC) for treating advanced refractory retinoblastoma (RB) in a large single-center cohort. Patients and Methods:Eighty-four eyes of 62 consecutive patients with advanced refractory RB who received IAC were included in the study dur...

journal_title：Journal of cancer research and therapeutics

authors： Hua J,Gang S,Yizhou J,Jing Z

更新日期：2018-01-01 00:00:00

abstract：Background:Colorectal cancer (CRC) is the second most diagnosed cancer often identified during the later stages of carcinogenesis. Orientin, a C-glycoside of luteolin, is well known for its versatile therapeutic action toward oxidative stress-induced cellular response may exert chemoprevention against CRC. Materials a...

journal_title：Journal of cancer research and therapeutics

authors： Thangaraj K,Natesan K,Settu K,Palani M,Govindarasu M,Subborayan V,Vaiyapuri M

更新日期：2018-10-01 00:00:00

abstract：:Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. ...

journal_title：Journal of cancer research and therapeutics

authors： Varnali E,Kavak A,Özkan Y,Karahacioglu FB

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Intracranial meningiomas are the second most common tumor of the CNS. The high-grade tumors are atypical and malignant meningioma comprising 5-7% and 1-3% of all meningiomas. The high-grade meningioma have an aggressive histopathological and clinical behavior. MATERIALS AND METHODS:We retrospectively revi...

journal_title：Journal of cancer research and therapeutics

authors： Kumar N,Kumar R,Khosla D,Salunke PS,Gupta SK,Radotra BD

更新日期：2015-10-01 00:00:00

abstract：Aims:Platinum-based chemotherapy is considered as the first-line treatment for nonsmall cell lung cancer (NSCLC) patients. However, platinum resistance and toxicity are major obstacles to its clinical applications. The two P-type ATPases ATP7A and ATP7B have been identified to play an essential role in the transport of...

journal_title：Journal of cancer research and therapeutics

authors： Li YQ,Zhang XY,Chen J,Yin JY,Li XP

更新日期：2018-01-01 00:00:00

abstract：:Mucoepidermoid carcinomas (MEC) are rare malignant tumors that originate in the submucosal bronchial glands, and complete resection usually correlates with favorable prognosis. A 54-year-old male patient was diagnosed with high-grade MEC in the left main bronchus via bronchoscopy. After the patient was diagnosed with ...

journal_title：Journal of cancer research and therapeutics

authors： Kuzucuoglu M,Karamustafaoglu YA,Cicin I,Yoruk Y

更新日期：2014-04-01 00:00:00

abstract：Objective:The objective of this paper is to identify ego networks and pathways in rheumatoid arthritis (RA) based on EgoNet algorithm and pathway enrichment analysis. Materials and Methods:The ego networks were identified based on the EgoNet algorithm which was comprised four steps: inputting gene expression data and ...

journal_title：Journal of cancer research and therapeutics

authors： Zhou WZ,Miao LG,Yuan H

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Tobacco use has been associated with various carcinomas including lung, esophagus, larynx, mouth, throat, kidney, bladder, pancreas, stomach, and cervix. Biomarkers such as concentration of cotinine in the blood, urine, or saliva have been used as objective measures to distinguish nonusers and users of tobac...

journal_title：Journal of cancer research and therapeutics

authors： Balhara YP,Jain R

更新日期：2013-01-01 00:00:00

abstract：:Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequentl...

journal_title：Journal of cancer research and therapeutics

authors： Patel GK,Perry JB,Abdul-Rahim O,Frankel AE,Cameron D,Taylor W,Rocconi RP,Abushahin L,Nelson C,Singh AP,Khushman M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Synovial sarcoma (SS) is a rare disease and compared with other soft-tissue sarcomas has a relatively high mortality rate. The optimal management of this disease and prognostic factors associated with patient outcome remains controversial. AIMS:We aimed to evaluate the factors affecting the outcomes of SS p...

journal_title：Journal of cancer research and therapeutics

authors： Tarkan Y,Erkan A,Selcuk ES,Mehmet K,Tugba KF,Ozlem US,Suleyman A,Tulay A,Bilge A,Ramazan Y,Yusuf G,Mevlude I,Umut D,Ilhan O,Abdurrahman I,Alper S,Dogan U,Necati A,Berna O,Gok DA,Ugur Y,Mahmut G

更新日期：2014-01-01 00:00:00

abstract：Background:The symptoms of patients with malignant biliary obstruction (MBO) could be effectively alleviated with percutaneous transhepatic biliary drainage (PTBD). Postoperative infections were considered as challenging issues for clinicians. In this study, the risk factors of biliary infection in patients after PTBD ...

journal_title：Journal of cancer research and therapeutics

authors： Yu H,Yuanyuan S,Guo Z,Xing W,Si T,Guo X,Liu F

更新日期：2018-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a common cancer world-wide with a higher incidence in Asia. Clear cell variant of HCC (CCHCC) has a frequency ranging from 0.4% to 37%. The presence of 90-100% clear cells is rare. In the present case, a 35-year-old female patient presented with fever and a large abdominal mass in the...

journal_title：Journal of cancer research and therapeutics

authors： Sakhuja P,Mishra PK,Rajesh R,Sharma AK,Gondal R,Singh M

更新日期：2015-07-01 00:00:00

abstract：:Toll-like receptors (TLRs) serve as specific pattern recognition molecules that bind to microbial components to activate innate immunity and instruct and modulate adaptive immunity in the face of immunological danger. Accumulating evidence supports that TLR signaling pathway responses to luminal microbes participate i...

journal_title：Journal of cancer research and therapeutics

authors： Lu Q,Ding H,Li W

更新日期：2013-11-01 00:00:00