Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review.

abstract：Background:Several studies have investigated hypopharyngeal cancer (HC) risk in combination with xenobiotic metabolism-related genetic polymorphisms and the burden of alcohol consumption and smoking in European countries but not in East Asian countries. Patients and Methods:This hospital-based case-control study invol...

journal_title：Journal of cancer research and therapeutics

authors： Yamashita Y,Ikegami T,Suzuki M,Hirakawa H,Maeda H,Yamada S,Deng Z,Kondo S,Kinjyo H,Kiyuna A,Agena S,Uehara T,Ganaha A

更新日期：2019-07-01 00:00:00

abstract：:Gardasil is the first quadrivalent human papillomavirus (HPV)-types 6, 11, 16, 18 recombinant vaccine approved by the FDA on June 8, 2006. It induces genotype-specific virus-neutralizing antibodies and prevents infection with HPV. Various clinical trials demonstrated a reduction in the incidence of vaccine-type-specif...

journal_title：Journal of cancer research and therapeutics

authors： Sharma R,Sharma CL

更新日期：2007-04-01 00:00:00

abstract：Background/Aim:Percutaneous thermal ablation combined with transarterial chemoembolization (TACE) becomes a treatment option for unresectable hepatocellular carcinoma (HCC). This study aims to investigate the safety and feasibility of percutaneous thermal ablation combined with simultaneous TACE for patients with HCC ≤...

journal_title：Journal of cancer research and therapeutics

authors： Wu M,Gao S,Song H,Zhang Z,Wang J,Liu R,Wang X,Cheng J,Luo J,Liu Q,Chen Y,Yan Z,Liu L

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Head and neck squamous cell carcinoma (HNSCC) represents as a common malignancy with increasing incidence in the worldwide. The fact of its poor survival rate urgently requires developing efficient predictive biomarkers for clinical use. MicroRNAs (miRNAs) recently represent as a novel direction for early dia...

journal_title：Journal of cancer research and therapeutics

authors： Wang H,Zhang G,Wu Z,Lu B,Yuan D,Li X,Lu Z

更新日期：2015-10-01 00:00:00

abstract：Introduction:Oxaliplatin-induced neurotoxicity is the single main dose-limiting factor in the treatment of colorectal cancer. The degree of neurotoxicity may be either acute and reversible or observed as cumulative and chronic peripheral nerve damage leading to peripheral neuropathy (PNP), walking difficulties, extremi...

journal_title：Journal of cancer research and therapeutics

authors： Banach M,Zygulska AL,Krzemieniecki K

更新日期：2018-07-01 00:00:00

abstract：Objectives:Apatinib, a tyrosine kinase inhibitor which selectively inhibits vascular endothelial growth factor receptor-2, has been shown to be beneficial to patients with a variety of cancers, including advanced nonsmall-cell lung cancer (NSCLC). Thus, this study was aimed to retrospectively assess the efficacy and sa...

journal_title：Journal of cancer research and therapeutics

authors： Yang C,Feng W,Wu D

更新日期：2018-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Biopsy Gleason score (b-GS) is often different from the Gleason score obtained after analysis of radical prostatectomy (RP) specimen (rp-GS). Upgradation has an important implication in decision making for cancer prostate management, and is the focus of this study. AIM:To evaluate Gleason score upgradation aft...

journal_title：Journal of cancer research and therapeutics

authors： Kulkarni JN,Valsangkar RS,Jadhav YR,Singh DP

更新日期：2011-10-01 00:00:00

abstract：:Doxorubicin (Adriamycin, ADM) is an antimitotic drug used in the treatment of a wide range of malignant tumors, including acute leukemia, lymphoma, osteosarcoma, breast cancer, and lung cancer. Multidrug resistance-associated proteins (MRPs) are members of a superfamily of ATP-binding cassette (ABC) transporters, whic...

journal_title：Journal of cancer research and therapeutics

authors： He Z,Hu B,Tang L,Zheng S,Sun Y,Sheng Z,Yao Y,Lin F

更新日期：2015-01-01 00:00:00

abstract：AIMS:To find out the efficacy of epidural analgesia in providing continuous pain relief for patients undergoing brachytherapy for cervical cancer. SETTINGS:Teaching Hospital. DESIGN:Retrospective Study. MATERIALS AND METHODS:A total of 152 patients of cervical cancer received epidural analgesia during 18 to 21 hours...

journal_title：Journal of cancer research and therapeutics

authors： Janaki MG,Nirmala S,Kadam AR,Ramesh BS,Sunitha KS

更新日期：2008-04-01 00:00:00

abstract：:Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. ...

journal_title：Journal of cancer research and therapeutics

authors： Varnali E,Kavak A,Özkan Y,Karahacioglu FB

更新日期：2020-07-01 00:00:00

abstract：:Many oral lesions may need to be diagnosed by removing a sample of tissue from the oral cavity. Biopsy is widely used in the medical field, but the practice is not quite widespread in dental practice. As oral pathologists, we have found many artifacts in the tissue specimen because of poor biopsy technique or handling...

journal_title：Journal of cancer research and therapeutics

authors： Kumaraswamy KL,Vidhya M,Rao PK,Mukunda A

更新日期：2012-04-01 00:00:00

abstract：AIMS:To compare three-dimensional conformal radiation therapy (3DCRT) and intensity-modulated radiation therapy (IMRT) in posterior fossa (PF) boost in children with medulloblastoma (MB); dosimetrically evaluating and comparing both techniques with regard to target coverage and doses to organs at risk. SETTINGS AND DE...

journal_title：Journal of cancer research and therapeutics

authors： Gupta M,Kant R,Nautiyal V,Bisht J,Raghuvanshi S,Saini M,Kalra BP,Ahmad M

更新日期：2017-10-01 00:00:00

abstract：:Acinic cell carcinoma (ACC) is a low-grade malignant salivary gland neoplasm that comprises approximately 17% of primary salivary gland malignancies or about 6% of all salivary gland neoplasms. The most common intraoral sites are the buccal mucosa, lips, and palate. The diagnosis of ACC frequently presents difficultie...

journal_title：Journal of cancer research and therapeutics

authors： Babu SS,Sunil S,Prathap A,Mathew AL

更新日期：2020-04-01 00:00:00

abstract：Purpose:Glioblastoma (GBM) is characterized by early relapse and mortality. Treatment resistance could be a characteristic exhibited by pro-genitor neoplastic cells that reside in the subventricular zone (SVZ). This retrospective study was conducted to assess the correlation of SVZ doses and survival in patients with G...

journal_title：Journal of cancer research and therapeutics

authors： Mathew BS,Kaliyath SB,Krishnan J,Bhasi S

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Oral submucous fibrosis (OSF) is a chronic irreversible condition of the oral mucosa with proven malignant potential. However, till date, there has been a dearth of effective management strategies. This study used alpha lipoic acid, an antioxidant, in oral form to determine if it could be usef...

journal_title：Journal of cancer research and therapeutics

authors： Rao PK

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Gemcitabine is the first-line drug for nonsmall cell lung cancer, and 18F-fluorodeoxyglucose. (18F-FDG) and 18F-fluorothymidine. (18F-FLT) are positron emission tomography. (PET) imaging agents. The aim of this study was to explore the effect of gemcitabine on the uptake of 18F-FDG and 18F-FLT in A549 cells ...

journal_title：Journal of cancer research and therapeutics

authors： Zhang B,Deng SM,Guo LC,Dong JJ,Zhu YB,Gao Y,Wang ZX,Cho WC

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the expression of Twist, E-cadherin, and N-cadherin both in normal endometrium and in endometrioid adenocarcinoma tissues (NET and EAT), and further discuss the relationship between the proteins expression and the clinical parameters. METHODS:Seventy-six EAT and 50 NET...

journal_title：Journal of cancer research and therapeutics

authors： Xie X,Zheng X,Wang J,Chen L

更新日期：2017-01-01 00:00:00

abstract：:Heart metastasis of renal cell carcinoma (RCC) without vena cava inferior involvement is exceptionally rare. Here, we presented a case of RCC presenting with the right ventricle metastasis without inferior vena caval and right atrial involvement. ...

journal_title：Journal of cancer research and therapeutics

authors： Sahin S,Karatas F,Hacioglu MB,Aytekin A,Cilbir E,Conkbayir I

更新日期：2018-01-01 00:00:00

abstract：:Chordoid meningioma (CM), classified as Grade II/atypical meningioma according to the World Health Organization classification, is a rare subtype, which represents only 0.5% of all meningiomas. Morphologically, it can mimic other chondroid and myxoid tumors within the brain and its vicinity thus posing a diagnostic ch...

journal_title：Journal of cancer research and therapeutics

authors： Siraj F,Ansari MK,Sharma KC,Singh A

更新日期：2015-07-01 00:00:00

abstract：:The aim of this work is to develop a wireless local area network (LAN) between different types of users (Radiation Oncologists, Radiological Physicists, Radiation Technologists, etc) for efficient patient data management and to made easy the availability of information (chair side) to improve the quality of patient ca...

journal_title：Journal of cancer research and therapeutics

authors： Mandal A,Asthana AK,Aggarwal LM

更新日期：2010-04-01 00:00:00

abstract：:Pituitary adenoma is one of the most common intracranial neoplasms, usually presenting with endocrinopathies or visual field defects. Granulomatous hypophysitis, one of the subtypes of primary hypophysitis, is a rare neurological entity presenting as a sellar lesion with mass effect symptoms and endocrinological dysfu...

journal_title：Journal of cancer research and therapeutics

authors： Mitra S,Chakraborty H

更新日期：2017-07-01 00:00:00

abstract：:Hodgkin's lymphoma of the breast is very rare. We report a case of Hodgkin's lymphoma of the breast in a 61 year old post-menopausal female who presented with a 3 month history of left breast painless lump. Excision biopsy was done and histology showed nodular sclerotic Hodgkin's lymphoma confirmed by immunohistochemi...

journal_title：Journal of cancer research and therapeutics

authors： Osuji CU,Ahaneku GI,Onwubuya EI,Okocha EC,Ukah C,Emegoakor CD,Omejua EG

更新日期：2013-07-01 00:00:00

abstract：Context:Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) play an indispensable role in the treatment of non-small cell lung cancer (NSCLC), leading to a survival major breakthrough, but there remains no uniform standard for predicting the efficacy of TKI therapy. Aims:We retrospectiv...

journal_title：Journal of cancer research and therapeutics

authors： Yu S,Wang X,Wang X,Wu X,Xu R,Wang X,Zhang X,Zhang C,Chen K,Cheng D,Wenfeng L

更新日期：2019-01-01 00:00:00

abstract：:Intra-nodal palisaded myofibroblastoma (IPM) is a rare benign lymph node mesenchymal tumor. It presents as a slow growing, painless nodular mass confined mostly to the inguinal area. Histologically, it shows palisading spindle cells, hemorrhages, hemosiderin laden macrophages, and amianthoid fibers, almost totally rep...

journal_title：Journal of cancer research and therapeutics

authors： Sarma NH,Arora KS,Varalaxmi KP

更新日期：2013-04-01 00:00:00

abstract：Aims:Platinum-based chemotherapy is considered as the first-line treatment for nonsmall cell lung cancer (NSCLC) patients. However, platinum resistance and toxicity are major obstacles to its clinical applications. The two P-type ATPases ATP7A and ATP7B have been identified to play an essential role in the transport of...

journal_title：Journal of cancer research and therapeutics

authors： Li YQ,Zhang XY,Chen J,Yin JY,Li XP

更新日期：2018-01-01 00:00:00

abstract：:Papillary carcinoma is a well-differentiated type of thyroid carcinoma with very good overall prognosis. The commonest site of metastases is the lymph node, distant metastases being rare. We present a case of a 52-year-old male who presented with a solitary metastasis in the left para-sellar region and cavernous sinus...

journal_title：Journal of cancer research and therapeutics

authors： Chandarana MN,Epari S,Chaukar D,Moiyadi AV

更新日期：2012-07-01 00:00:00

abstract：:While most case reports to date are radiation recall dermatitis, radiation recall myositis, which is a distinct form of radiation recall phenomenon caused by carboplatin plus paclitaxel, has not been reported. We treated a 57-year-old female patient who suffered from recurrent cervical cancer. When the patient develop...

journal_title：Journal of cancer research and therapeutics

authors： Maeng CH,Park JS,Lee SA,Kim DH,Yun DH,Yoo SD,Kim HS,Chon J

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The epidural anesthesia and general anesthesia are the most commonly used in lung surgery through video-assisted thoracic surgery (VATS). Each of these methods has their advantages and disadvantages, so the aim of this meta-analysis is to identify which anesthesia is more conducive to lung surgery under VATS ...

journal_title：Journal of cancer research and therapeutics

authors： Ke JD,Hou HJ,Wang M,Zhang YJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Prostate-specific membrane antigen (PSMA) is a widely used targeted molecule in prostate patients. The present research, attempts to support the hypothesis that PSMA expression in prostate cancer stem cell-like (CSC) cell populations may be correlated with nanog and other transcription factors in different s...

journal_title：Journal of cancer research and therapeutics

authors： Maria T,Panagiotis A,Marina C,Eleni K,Ioanna V,Georgia M,Ioannis P

更新日期：2014-01-01 00:00:00