Radiation recall phenomenon presenting as myositis triggered by carboplatin plus paclitaxel and related literature review.

Abstract:

:While most case reports to date are radiation recall dermatitis, radiation recall myositis, which is a distinct form of radiation recall phenomenon caused by carboplatin plus paclitaxel, has not been reported. We treated a 57-year-old female patient who suffered from recurrent cervical cancer. When the patient developed a new left sacral metastasis, salvage radiotherapy (total dose 60 Gy) was administered. Four weeks later, chemotherapy using carboplatin plus paclitaxel was initiated. Four months after chemotherapy, the patient complained of severe pain in her left buttock. On magnetic resonance imaging (MRI), edematous changes and increased signal densities of left gluteus maximus and medius muscles were noted suggesting myositis. The border of the high signal intensity territory of the muscles was sharp and clearly corresponded with the recent irradiation field. We concluded that the patient had radiation recall myositis triggered by paclitaxel-carboplatin. Symptoms were controlled by analgesics, and there was no recurrence.

journal_name

J Cancer Res Ther

authors

Maeng CH,Park JS,Lee SA,Kim DH,Yun DH,Yoo SD,Kim HS,Chon J

doi

10.4103/0973-1482.146090

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

1093-7

issue

4

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2014_10_4_1093_146090

journal_volume

10

pub_type

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