ATP7B rs9535826 is associated with gastrointestinal toxicity of platinum-based chemotherapy in nonsmall cell lung cancer patients.

abstract：:Burkitt's lymphoma is an uncommon form of non-Hodgkin's lymphoma (NHL) in adults and represents < 5% of NHL adults. Burkitt's lymphoma involving primarily the appendicular skeleton is rarely described. We present the case of a young man with primary Burkitt's lymphoma involving the humerus as the only site of disease....

journal_title：Journal of cancer research and therapeutics

authors： Geetha N,Sreelesh KP,Nair RA,Jacob PM

更新日期：2015-10-01 00:00:00

abstract：:Prostate cancer, one of the most common male malignancies with an increasing incidence in the recent years, requires the development of new methods of treatment. One of the most debated subjects is the tumor-associated macrophages (TAM). Although, the pathophysiological mechanisms are still a subject of intense resear...

journal_title：Journal of cancer research and therapeutics

authors： Nenu I,Gafencu GA,Popescu T,Kacso G

更新日期：2017-07-01 00:00:00

abstract：Objective:To discuss and assess the clinical value of treating lung cancer cachexia with thalidomide combined with cinobufagin.s. Methods:A cohort of 54 patients, who were diagnosed with lung carcinoma, was randomly divided into two groups, a trial group and a control group, respectively. The trial group was given 150...

journal_title：Journal of cancer research and therapeutics

authors： Xie M,Chen X,Qin S,Bao Y,Bu K,Lu Y

更新日期：2018-01-01 00:00:00

abstract：Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated ...

journal_title：Journal of cancer research and therapeutics

authors： Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari F

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Mucin 13 (MUC13) and Mucin 20 (MUC20) are high molecular weight transmembrane O-linked glycoprotein secreted by epithelium and are widely overexpressed in epithelial tumor cells. Previously, it has been reported that MUC13 and MUC20 were prognostic molecular biomarkers of some epithelial tumors, but few has ...

journal_title：Journal of cancer research and therapeutics

authors： Wang H,Shen L,Lin Y,Shi Q,Yang Y,Chen K

更新日期：2015-08-01 00:00:00

abstract：:Radiofrequency ablation (RFA) recently has been applied to benign thyroid nodules, mainly for the cosmetic reasons, and limited cases of local recurrences or focal distant metastases of well-differentiated thyroid cancer, in the high-risk reoperative condition or for the palliative purpose. But no report has been made...

journal_title：Journal of cancer research and therapeutics

authors： Kim HY,Ryu WS,Woo SU,Son GS,Lee ES,Lee JB,Bae JW

更新日期：2010-07-01 00:00:00

abstract：:Adjuvant treatment options for Stage I seminoma include active surveillance, chemotherapy, and radiotherapy. Active surveillance may not be ideal for the average Indian patient. Of the two accepted adjuvant therapy options, namely single-dose carboplatin chemotherapy and radiotherapy to the retroperitoneal nodes, thou...

journal_title：Journal of cancer research and therapeutics

authors： Yathiraj PH,Sharan K,Fernandes DJ,Vidyasagar MS

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Oral cancer is the third most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Transformation of normal tissue to premalignant lesion and further to oral cancer results in alteration in glycolytic pathway and hence the lactate dehydrogenase levels. Therefore...

journal_title：Journal of cancer research and therapeutics

authors： Shetty SR,Chadha R,Babu S,Kumari S,Bhat S,Achalli S

更新日期：2012-01-01 00:00:00

abstract：:A 29-year-old hypertensive male with von Hippel-Lindau (VHL) syndrome came to the Endocrinology department for evaluation. Contrast-enhanced computed tomography of the abdomen revealed an adrenal mass, bilateral renal cell carcinoma, and multiple pancreatic cysts. The hormonal investigations for adrenal mass were norm...

journal_title：Journal of cancer research and therapeutics

authors： Palui R,Kamalanathan S,Sahoo J,Dorairajan LN,Badhe B,Gochhait D

更新日期：2019-03-01 00:00:00

abstract：:Heat shock protein 90 (Hsp90) a member of the heat shock proteins (HSPs) family, is an adenosine triphosphate dependent molecular chaperone protein, which integrates multiple oncogenic pathways. Clinically, encouraging results have been demonstrated in melanoma, acute myeloid leukemia, castrate refractory prostate can...

journal_title：Journal of cancer research and therapeutics

authors： Routray S,Sunkavalli A,Swain N,Shankar AA

更新日期：2013-10-01 00:00:00

abstract：AIM OF STUDY:To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver nanoparticles (SNs) to tumor growth in a murine model. MATERIALS AND METHODS:Sanazole (AK) and DOX were complexed with SNs, individually and in combination to obtain SN-AK, SN-DOX, and SN-AK-DOX....

journal_title：Journal of cancer research and therapeutics

authors： Nair GG,Nair CK

更新日期：2014-10-01 00:00:00

abstract：Objective:The association between asthma and the risk of prostate cancer remains elusive. We aimed to evaluate the relationship between asthma and the onset of prostate cancer. Methods:We searched PubMed, Embase, and Cochrane databases for articles that assessed the association of asthma with the risk of prostate canc...

journal_title：Journal of cancer research and therapeutics

authors： Li W,Mao S,Tu M,Ge X,Li K,Xie F,Song Y,Miao Y

更新日期：2018-09-01 00:00:00

abstract：:Small fields are more repeatedly used for radiation therapy as small segments in intensity-modulated radiotherapy or as in the form of independent fields in stereotactic radiosurgery and other novel equipment such as cyberknife and tomotherapy. Nevertheless, the application of small fields for radiotherapy of lung mak...

journal_title：Journal of cancer research and therapeutics

authors： Bagheri H,Soleimani A,Gharehaghaji N,Mesbahi A,Manouchehri F,Shekarchi B,Dormanesh B,Dadgar HA

更新日期：2017-04-01 00:00:00

abstract：:Many oral lesions may need to be diagnosed by removing a sample of tissue from the oral cavity. Biopsy is widely used in the medical field, but the practice is not quite widespread in dental practice. As oral pathologists, we have found many artifacts in the tissue specimen because of poor biopsy technique or handling...

journal_title：Journal of cancer research and therapeutics

authors： Kumaraswamy KL,Vidhya M,Rao PK,Mukunda A

更新日期：2012-04-01 00:00:00

abstract：:Toll-like receptors (TLRs) serve as specific pattern recognition molecules that bind to microbial components to activate innate immunity and instruct and modulate adaptive immunity in the face of immunological danger. Accumulating evidence supports that TLR signaling pathway responses to luminal microbes participate i...

journal_title：Journal of cancer research and therapeutics

authors： Lu Q,Ding H,Li W

更新日期：2013-11-01 00:00:00

abstract：Purpose:Programmed death ligand-1 (PD-L1) is the main ligand for programmed death-1 (PD-1), and is one of the major targets for cancer immunotherapy. Only a few studies are available for the clinical significance of PD-1/PD-L1 in nasopharyngeal carcinoma (NPC). There is a controversial association between PD-L1 express...

journal_title：Journal of cancer research and therapeutics

authors： Sahinli H,Akyürek N,Yılmaz M,Kandemir O,Duran AO,Kulaçoǧlu S,Uçar G,Acar E,Özet A,Öksüzoǧlu OBÇ,Özdemir NY

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The perioperative use of epirubicin, cisplatin, and fluorouracil (ECF) significantly improves outcomes in patients with gastric and gastro-oesophageal (GO) cancers but is cumbersome to administer. Given the equivalence of epirubicin, oxaliplatin, and capectabine (EOX) with ECF in advanced setting, we analyze...

journal_title：Journal of cancer research and therapeutics

authors： Sirohi B,Barreto SG,Singh A,Batra S,Mittra A,Rastogia S,Ramadwar M,Shetty N,Goel M,Shrikhande SV

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine age-specific incidence ratios, gastric cancer localization trend, histologic subtype and cancer related survival that whether have changed during the period from 1999 to 2010. MATERIALS AND METHODS:A total of 866 gastric cancer patients treated at the hospital were retr...

journal_title：Journal of cancer research and therapeutics

authors： Tural D,Selçukbiricik F,Akar E,Serdengeçti S,Büyükünal E

更新日期：2013-10-01 00:00:00

abstract：:Chondroblastoma is a rare, benign tumor derived from chondroblasts, commonly presenting in the second decade of life. It is usually found in the epiphysis or apophysis of long bones; however, it may rarely affect flat bones like scapula. Occasionally a histologically typical chondroblastoma may exhibit an aggressive b...

journal_title：Journal of cancer research and therapeutics

authors： Dhanda S,Menon S,Gulia A

更新日期：2015-07-01 00:00:00

abstract：AIM:To determine the efficacy of belly board device in patients receiving postoperative radiation for gynecological malignancies in terms of setup error and acute small bowel toxicity. MATERIALS AND METHODS:Patients requiring postoperative radiation for gynecological malignancies were prospectively randomized to eithe...

journal_title：Journal of cancer research and therapeutics

authors： Anjanappa M,Raghavan RK,James FV,Kumar A,Mathews S,Bhaskaran S,Sreedevi SV,Jayaprakash PG

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Ramucirumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody targeting vascular endothelial growth factor receptor-2 (VEGFR-2), has been approved for the treatment of advanced gastric cancer or gastroesophageal junction adenocarcinoma. Hypertension has been described as a common adverse event with...

journal_title：Journal of cancer research and therapeutics

authors： Qi WX,Fu S,Zhang Q,Guo XM

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The aim of this retrospective study was to evaluate the clinical efficacy and prognosis of breast-conserving surgery versus modified radical mastectomy in the treatment of early stage breast cancer. PATIENTS AND METHODS:Two hundred and nineteen cases of early stage breast cancer were reviewed and retrospecti...

journal_title：Journal of cancer research and therapeutics

authors： Chen Z,Xu Y,Shu J,Xu N

更新日期：2015-08-01 00:00:00

abstract：:[This corrects the article DOI: 10.4103/0973-1482.180685]. ...

journal_title：Journal of cancer research and therapeutics

authors：

更新日期：2019-10-01 00:00:00

abstract：:We herein describe a case of drug-induced interstitial lung disease (ILD) following treatment with erlotinib. The plasma trough concentration of erlotinib at the time of the ILD diagnosis was extremely elevated compared with the plasma maximum concentration on day 1. We hypothesized that this phenomenon was associated...

journal_title：Journal of cancer research and therapeutics

authors： Tsubata Y,Hamada A,Sutani A,Isobe T

更新日期：2012-01-01 00:00:00

abstract：:The management of patients with the clinically negative neck (N0) in early oral cancers awaits a clear mandate despite growing evidence favoring elective neck dissection. Having a general policy of operating all N0 neck may indeed increase the number of unnecessary neck dissection in the true pathological N0 necks, a ...

journal_title：Journal of cancer research and therapeutics

authors： Rao VU,Patil PH,Rajaram BV

更新日期：2016-07-01 00:00:00

abstract：:Choriocarcinoma is the most malignant tumor of gestational trophoblast origin. Metastasis to brain is considered a poor prognostic indicator. Recent advances in adjuvant radiotherapy and chemotherapy have led to an excellent outcome of these patients. Craniotomy is indicated in selected cases with cerebral metastases....

journal_title：Journal of cancer research and therapeutics

authors： Dadlani R,Furtado SV,Ghosal N,Prasanna KV,Hegde AS

更新日期：2010-10-01 00:00:00

abstract：AIM OF STUDY:Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. Recently, genome-wide association studies have identified two single nucleotide polymorphisms (SNP) associated with CRC in Caucasians. MATERIALS AND METHODS:To validate whether the same variation...

journal_title：Journal of cancer research and therapeutics

authors： Qiao HP,Zhang CY,Yu ZL,Li QM,Jiao Y,Cao JP

更新日期：2015-04-01 00:00:00

abstract：AIM:To evaluate the integral dose to carotid vessels in extended field intensity modulated radiotherapy (IMRT) (including the lower neck nodes in IMRT field) and split field IMRT (using separate single anterior field to treat lower neck nodes) in cancer nasopharynx. MATERIALS AND METHODS:Dosimetric data from 10 patien...

journal_title：Journal of cancer research and therapeutics

authors： Bahl A,Basu KS,Sharma DN,Rath GK,Julka PK,Thulkar S

更新日期：2010-10-01 00:00:00

abstract：Context:Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims:In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design:The proposed system includes three m...

journal_title：Journal of cancer research and therapeutics

authors： Zarbakhsh P,Addeh A

更新日期：2018-04-01 00:00:00

abstract：Objective:In this study, we showed a modified method for the isolation of cancer stem cells (CSCs) using a combination of differential adhesion method and serum-free culture medium (SFM) method. Materials and Methods:Trypsin-sensitive cells and trypsin-resistant cells were isolated from MB49, EJ, and SK-OV-3 cells usi...

journal_title：Journal of cancer research and therapeutics

authors： Zhu YT,Wang CY,Pang SY,Lei CY,Luo Y,Tan WL

更新日期：2018-06-01 00:00:00