Abstract:
Objective:To discuss and assess the clinical value of treating lung cancer cachexia with thalidomide combined with cinobufagin.s. Methods:A cohort of 54 patients, who were diagnosed with lung carcinoma, was randomly divided into two groups, a trial group and a control group, respectively. The trial group was given 150 mg/day thalidomide and 2700 mg/day cinobufagin; the control group only received 2,700 mg/day cinobufagin. The therapy lasted for 12 weeks, and the nutritional status, quality of life, survival, and side effects in patients in the two groups were recorded. Results:The nutritional status, quality of life, and survival of patients with lung cancer cachexia in the trial group were significantly improved compared to the control group. The trial group received 150 mg thalidomide, which by contrast reduced the incidence of side effect and increased tolerance. Conclusion:Using thalidomide combined with cinobufagin to treat patients with lung cancer cachexia will significantly improve their nutritional status and quality of life. This therapy is better than that using cinobufagin alone and is well tolerated.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Xie M,Chen X,Qin S,Bao Y,Bu K,Lu Ydoi
10.4103/0973-1482.188436subject
Has Abstractpub_date
2018-01-01 00:00:00pages
226-232issue
1eissn
0973-1482issn
1998-4138pii
JCanResTher_2018_14_1_226_188436journal_volume
14pub_type
杂志文章abstract:BACKGROUND:Synovial sarcoma (SS) is a rare disease and compared with other soft-tissue sarcomas has a relatively high mortality rate. The optimal management of this disease and prognostic factors associated with patient outcome remains controversial. AIMS:We aimed to evaluate the factors affecting the outcomes of SS p...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,多中心研究
doi:10.4103/0973-1482.131381
更新日期:2014-01-01 00:00:00
abstract:Context:Colorectal cancers are frequent among cancers of gastrointestinal system. Whether there are any differences between survival in rectum and colon cancer patients is controversial. Aims:In this study, we aimed to compare survival in surgically treated rectum and colon cancers and determine the factors affecting ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.199390
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this meta-analysis was to evaluate the predictive value of cervical lymph node metastasis through sentinel lymph node biopsy (SLNB) in patients with oral cancer. MATERIALS AND METHODS:Two authors independently searched the databases of PubMed, Cochrane central register of controlled trials, EM...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
doi:10.4103/0973-1482.200751
更新日期:2016-12-01 00:00:00
abstract:Introduction:Human papillomavirus (HPV) is emerging as a risk factor for esophageal squamous carcinoma. The prognostic value of the HPV status has been investigated. However, the results are much controversial. Aim:This study aims to document the association of HPV infection and mutation of p53 gene in esophageal squa...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_296_17
更新日期:2020-12-01 00:00:00
abstract:Aim:This randomized phase III trial compared hepatic arterial infusion (HAI) chemotherapy with 5-fluorouracil (5-FU) followed by uracil/tegafur (UFT) and leucovorin (LV) versus UFT/LV alone for patients with curatively resected liver metastases from colorectal cancer (CRC). Methods:The study was designed to include 28...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,随机对照试验
doi:10.4103/0973-1482.179188
更新日期:2018-09-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 信件
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更新日期:2017-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2006-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_1031_17
更新日期:2018-01-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.77105
更新日期:2010-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 信件
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更新日期:2015-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2008-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.87022
更新日期:2011-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.168189
更新日期:2015-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.187387
更新日期:2018-10-01 00:00:00
abstract:Purpose:We aimed to report the experience of intraoperative electron radiation therapy (IOERT) with Mobetron (Intraop Medical Incorporated, Santa Clara, CA, USA) as a partial breast irradiation (PBI) for patients with early-stage breast cancer and explanation of IOERT application and present early clinical and cosmetic...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_191_17
更新日期:2019-07-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
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journal_title:Journal of cancer research and therapeutics
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
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journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
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journal_title:Journal of cancer research and therapeutics
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更新日期:2020-10-01 00:00:00
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journal_title:Journal of cancer research and therapeutics
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更新日期:2015-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00