Unusual clinical and radiological presentation of metastatic choriocarcinoma to the brain and long-term remission following emergency craniotomy and adjuvant EMA-CO chemotherapy.

Abstract:

:Choriocarcinoma is the most malignant tumor of gestational trophoblast origin. Metastasis to brain is considered a poor prognostic indicator. Recent advances in adjuvant radiotherapy and chemotherapy have led to an excellent outcome of these patients. Craniotomy is indicated in selected cases with cerebral metastases. The authors report an interesting case of an aggressive choriocarcinoma with multiple metastases to the brain and viscera. The patient had radiological evidence of new lesions occurring almost every week while on the initial treatment and yet had a complete long-term remission with EMA-CO therapy. The interesting presentation, radiology and adjuvant therapies are discussed.

journal_name

J Cancer Res Ther

authors

Dadlani R,Furtado SV,Ghosal N,Prasanna KV,Hegde AS

doi

10.4103/0973-1482.77069

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

552-6

issue

4

eissn

0973-1482

issn

1998-4138

pii

JCanResTher_2010_6_4_552_77069

journal_volume

6

pub_type

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