Abstract:
:The well-being of young cancer survivors is hampered due to the toxic effects of chemotherapy on the ovaries, resulting in infertility. We report a case of a 42-year-old woman with a history of bilateral ductal carcinoma of the breast who underwent radical mastectomy with chemotherapy and radiotherapy was anxious to conceive. In vitro fertilization was performed with donor oocyte; the patient became pregnant and delivered a full term baby with no congenital anomalies. As very few have a background for providing guidance and treatment in this setting, this report highlights the possibility of improving the quality of reproductive life of young survivors by various assisted reproductive techniques, the importance of fertility preservation and a multidisciplinary team approach.
journal_name
J Cancer Res Therjournal_title
Journal of cancer research and therapeuticsauthors
Muthuvel VA,Ravindran M,Chander VA,Gounder CVdoi
10.4103/0973-1482.174556subject
Has Abstractpub_date
2018-07-01 00:00:00pages
1157-1159issue
5eissn
0973-1482issn
1998-4138pii
JCanResTher_2018_14_5_1157_174556journal_volume
14pub_type
信件abstract::Epithelial-mesenchymal transition (EMT), a key developmental program has been shown to occur in wound healing, organ fibrosis and in the initiation of metastasis for cancer progression. EMT is a process that describes the development of motile, mesenchymal-like cells from non-motile parent epithelial cells. Plasticity...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.137926
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:The objective of the study is to investigate whether hospital-based transitional care can reduce the postoperative complication in patients who received enterostomy or not by pooling the published prospective clinical studies. MATERIALS AND METHODS:Prospective clinical studies related to hospital-based trans...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析
doi:10.4103/0973-1482.191637
更新日期:2016-10-01 00:00:00
abstract:Background:Several studies have investigated hypopharyngeal cancer (HC) risk in combination with xenobiotic metabolism-related genetic polymorphisms and the burden of alcohol consumption and smoking in European countries but not in East Asian countries. Patients and Methods:This hospital-based case-control study invol...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_980_17
更新日期:2019-07-01 00:00:00
abstract:AIM:To study the clinico-radiological and clinic-pathological features of orbital alveolar soft-part sarcomas (ASPS). MATERIALS AND METHODS:We retrieved 9 cases of orbital ASPS. Histopathological and immunohistochemical features and clinico-radiological findings were evaluated. RESULTS:Age at presentation varied from...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.136570
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Prostate-specific membrane antigen (PSMA) is a widely used targeted molecule in prostate patients. The present research, attempts to support the hypothesis that PSMA expression in prostate cancer stem cell-like (CSC) cell populations may be correlated with nanog and other transcription factors in different s...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.131461
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The effect of heparin in improving cancer survival has gained increasing attention over the past decades. Several clinical trials have evaluated the role of heparin on survival outcome and its safety profile in lung cancer patients. Thus, we performed a systematic review and meta-analysis from the results of...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,meta分析,评审
doi:10.4103/0973-1482.191627
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:We seek to investigate whether carboplatin-based induction chemotherapy before modern day concurrent chemoradiotherapy (CCRT) improves survival in patients with bulky, locally advanced nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS:This analysis included 105 patients with Stage II and III NSCLC tr...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.177214
更新日期:2016-04-01 00:00:00
abstract::Gardasil is the first quadrivalent human papillomavirus (HPV)-types 6, 11, 16, 18 recombinant vaccine approved by the FDA on June 8, 2006. It induces genotype-specific virus-neutralizing antibodies and prevents infection with HPV. Various clinical trials demonstrated a reduction in the incidence of vaccine-type-specif...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.34686
更新日期:2007-04-01 00:00:00
abstract::Primary pulmonary epithelioid angiosarcoma is an extremely rare malignancy. Herein, we report the case of an elderly Chinese patient with primary pulmonary epithelioid angiosarcoma. The 72-year-old man presented with a 1-month history of persistent hemoptysis and left chest pain and weight loss of 3 kg. A chest comput...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件,评审
doi:10.4103/0973-1482.176419
更新日期:2018-06-01 00:00:00
abstract:AIM OF STUDY:The aim of this study was to analyze the clinical features and outcomes of thyroid carcinoma (TC) in children and adolescent population treated in our institution. MATERIALS AND METHODS:We gathered 43 TC patients 18 years of age or under initial diagnosed between 2009 and 2010 from two hospitals. Patient'...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,多中心研究
doi:10.4103/jcrt.JCRT_167_16
更新日期:2017-01-01 00:00:00
abstract:Context:Breast cancer is a major cause of mortality in young women in the developing countries. Early diagnosis is the key to improve survival rate in cancer patients. Aims:In this paper an intelligent system is proposed to breast cancer tumor type recognition. Settings and Design:The proposed system includes three m...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.183561
更新日期:2018-04-01 00:00:00
abstract:Aims:This study aims at assessing the volume changes that occur in the targets (gross tumor volume and planning target volume [PTV]) and the organs at risk in squamous cell carcinoma of the head and neck during radiotherapy and assessing the dose changes that occur as a result of them. Settings and Design:This was a p...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_589_19
更新日期:2020-04-01 00:00:00
abstract::Melanoma is rare in children, but its incidence appears to be increasing. Melanoma accounts for the highest mortality among all skin cancer types. This disease is characterized by high-grade malignancy, easy metastasis, poor prognosis, and high death rate. Melanoma in children may be biologically different from that i...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.145788
更新日期:2014-11-01 00:00:00
abstract::Dermatofibrosarcoma protuberans (DFSP) is a low-grade tumor with rare metastasis. A 26-year-old male presented with multiple cutaneous nodular lesions of DFSP since 3 months along with distant metastasis to the brain, pleura, and muscles that were detected on investigations. The case is being reported due to its rare ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.146099
更新日期:2015-07-01 00:00:00
abstract:Introduction:The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established. We perform a single institutional retrospective study of CRT in terms of toxicity in elderly patients (age more than 60 years) as compared with young cohort (age <60 years)...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_878_18
更新日期:2020-01-01 00:00:00
abstract:Background:Ghrelin plays a role in mechanisms related to cancer progression - including cell proliferation, invasion and migration, and resistance to apoptosis in the cell lines from several cancers. We investigated the role of ghrelin levels in cancer cachexia-anorexia in patients with locally advanced nonsmall-cell l...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:110.4103/jcrt.JCRT_10_19
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Mucin 13 (MUC13) and Mucin 20 (MUC20) are high molecular weight transmembrane O-linked glycoprotein secreted by epithelium and are widely overexpressed in epithelial tumor cells. Previously, it has been reported that MUC13 and MUC20 were prognostic molecular biomarkers of some epithelial tumors, but few has ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.163846
更新日期:2015-08-01 00:00:00
abstract:Aims:The role of prophylactic central neck dissection (CND) in the management of papillary thyroid carcinoma (PTC) is controversial. This study reports outcomes of an observational approach in PTC patients without clinical evidence of lymph node metastasis. Materials and Methods:Patients with PTC who had surgery (with...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_620_19
更新日期:2020-09-01 00:00:00
abstract:AIM:Concurrent chemoradiotherapy (CRT) is the standard therapy for patients with unresectable Stage III nonsmall cell lung cancer (NSCLC). The aim of this study was to assess the efficacy and safety of concurrent CRT in unresectable Stage III NSCLC in Turkey. PATIENTS AND METHODS:The study included 82 patients with hi...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.163682
更新日期:2016-01-01 00:00:00
abstract::Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/jcrt.JCRT_212_17
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Somatic mutations of the epidermal growth factor receptor (EGFR) gene have been associated with tumor response to tyrosine kinase inhibitors (TKIs) and favorable outcome in patients with non-small-cell lung cancer (NSCLC). The activating mutations that confer sensitivity to EGFR TKIs are present in the TK do...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.147711
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess Ezrin expression in the primary hepatic carcinoma patients and associated with clinical, pathological characteristics. MATERIALS AND METHODS:Fifty-one patients with primary hepatocellular carcinoma (PHC) with completed clinical data were retrospectively analyzed in this st...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.200761
更新日期:2016-12-01 00:00:00
abstract::Squamous cell carcinoma of urinary tract is a rarely encountered tumor. It is more frequently reported in urinary bladder and male urethra than renal pelvis. Squamous cell carcinoma of renal pelvis is usually associated with nephrolithiasis. However, coexistence of keratinizing squamous cell carcinoma with xanthogranu...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.73351
更新日期:2010-07-01 00:00:00
abstract:Context:The metastasis of liver cancer is a major cause of clinical treatment failure, restrain, and control the cancer metastasis is the major strategy of the treatment and prevention of the disease. Special AT-rich sequence-binding protein 1 (SATB1) gene was overexpressed in many malignant tumors and considered as a ...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.203597
更新日期:2018-12-01 00:00:00
abstract::Rectal cancers may rarely metastasize in bone and when it occurs, is usually preceded by lung and/or liver metastasis. However, whether it may ever bypasses other organs, particularly lung and liver and metastasizes directly to bone or not, is debatable. Some authors have described the presence of isolated bone metast...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.136675
更新日期:2014-04-01 00:00:00
abstract::Lymphoma of the salivary gland accounts for 5% of cases of extranodal lymphoma and 10% of malignant salivary gland tumors. Most primary salivary gland lymphomas are B marginal zone lymphomas arising on a background of sialadenitis associated with an autoimmune disorder such as Sjorgen's syndrome. This report describes...
journal_title:Journal of cancer research and therapeutics
pub_type: 信件
doi:10.4103/0973-1482.106586
更新日期:2012-10-01 00:00:00
abstract:Objective:The objective of this study is to evaluate health literacy level, cervical cancer knowledge, and practice among women patients undergoing screening. Materials and Methods:A cross-sectional study was conducted among 455 women family health center patients. Health literacy level was evaluated by Rapid Estimate...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/jcrt.JCRT_1142_16
更新日期:2019-10-01 00:00:00
abstract::Adjuvant treatment options for Stage I seminoma include active surveillance, chemotherapy, and radiotherapy. Active surveillance may not be ideal for the average Indian patient. Of the two accepted adjuvant therapy options, namely single-dose carboplatin chemotherapy and radiotherapy to the retroperitoneal nodes, thou...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章,评审
doi:10.4103/0973-1482.176171
更新日期:2016-10-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/0973-1482.163868.]. ...
journal_title:Journal of cancer research and therapeutics
pub_type: 已发布勘误
doi:10.4103/0973-1482.197539
更新日期:2016-07-01 00:00:00
abstract::Hodgkin's lymphoma of the breast is very rare. We report a case of Hodgkin's lymphoma of the breast in a 61 year old post-menopausal female who presented with a 3 month history of left breast painless lump. Excision biopsy was done and histology showed nodular sclerotic Hodgkin's lymphoma confirmed by immunohistochemi...
journal_title:Journal of cancer research and therapeutics
pub_type: 杂志文章
doi:10.4103/0973-1482.119369
更新日期:2013-07-01 00:00:00